- What is metronidazole cream, and how does it work (mechanism of action)?
- What are the side effects of metronidazole cream?
- What is the dosage for metronidazole cream?
- Which drugs or supplements interact with metronidazole cream?
- Is metronidazole cream safe to take if I'm pregnant or breastfeeding?
- What else should I know about metronidazole cream?
What is metronidazole cream, and how does it work (mechanism of action)?
Metronidazole cream is a topical preparation (applied to the skin) of the antibiotic metronidazole. It is used for reducing the swelling and redness caused by acne rosacea. The mechanism through which metronidazole cream reduces the symptoms of acne rosacea is not known. The FDA approved metronidazole cream in September 1997.
What brand names are available for metronidazole cream?
Noritate, Metrocream
Is metronidazole cream available as a generic drug?
Yes
Do I need a prescription for metronidazole cream?
Yes
What are the side effects of metronidazole cream?
Side effects are rare and minor. These include:
- irritation,
- skin dryness,
- scaling, and itching at the site of application.
Individuals that are allergic to metronidazole should not use metronidazole cream.
What is the dosage for metronidazole cream?
Metronidazole cream is applied to affected areas once or twice daily. The affected areas should be cleaned before application, and then a thin film should be applied and rubbed into the skin. Makeup may be used after metronidazole cream has been applied. Metronidazole cream is for external use only. Contact with the eyes should be avoided.
Which drugs or supplements interact with metronidazole cream?
Drug interactions with metronidazole cream are unlikely because only small amounts of metronidazole are absorbed into the body when metronidazole cream is applied to the skin. Oral metronidazole interacts with warfarin (Coumadin), increasing the blood-thinning effects of warfarin. It is not known whether the small amounts of metronidazole absorbed via the skin can cause the same interaction.
Is metronidazole cream safe to take if I'm pregnant or breastfeeding?
There are no adequate studies of metronidazole cream in pregnant women.
When metronidazole is administered orally it is secreted into breast milk in concentrations similar to the concentration in the mothers body. Therefore, small amounts of metronidazole that are absorbed into the body when metronidazole cream is used may be secreted into breast milk.
What else should I know about metronidazole cream?
What preparations of metronidazole cream are available?
Cream: 0.75 and 1%
How should I keep metronidazole cream stored?
Metronidazole cream should be stored at room temperature, 15 C - 30 C (59 F - 86 F)

IMAGES
Rosacea Browse our medical image collection of bacterial skin conditions such as follicultis, scarlet fever, and more See ImagesSummary
Metronidazole cream (Noritate, Metrocream) is a topical cream is used to treat the swelling and redness caused by acne rosacea. Side effects, drug interactions, and pregnancy safety information should be reviewed prior to using this drug.
Multimedia: Slideshows, Images & Quizzes
Related Disease Conditions
-
Bacterial Vaginosis (BV)
Bacterial vaginosis is an abnormal vaginal condition with signs and symptoms of vaginal discharge, vaginal odor, and vaginal pain. It results from an overgrowth of normal bacteria in the vagina.
-
Rosacea
Rosacea is a skin disease that causes redness of the forehead, chin, and lower half of the nose. In addition to inflammation of the facial skin, symptoms include dilation of the blood vessels and pimples (acne rosacea) in the middle third of the face. Oral and topical antibiotics are treatments for rosacea. If left untreated, rhinophyma (a disfiguring nose condition) may result.
-
Acne (Pimples)
Acne is a localized skin inflammation as a result of overactivity of oil glands at the base of hair follicles. This inflammation, depending on its location, can take the form of a superficial pustule (contains pus), a pimple, a deeper cyst, congested pores, whiteheads, or blackheads. Treatments vary depending on the severity of the acne.
-
Is Diverticulitis Contagious?
Diverticulitis is an inflammation of the diverticula or diverticulum. Diverticulitis causes are either infectious or noninfectious, however, it is not contagoius. Symptoms of diverticulitis include: nausea, vomiting, diarrhea, gas, constipation, changes in bowel habits, bloating, constipation, fever, abdominal tenderness, swollen abdomen, fistula formation, and lower left abdominal pain.
-
Yeast Infection vs. Bacterial Vaginosis (BV)
Yeast infections and bacterial vaginosis (BV) both cause vaginal discharge. Yeast infection discharge is thick, white, and had a cottage cheese consistency. BV discharge is whitish-gray and is thinner. Vaginal odor, irritation, and pain may also be present. Treatment of yeast infections includes over-the-counter and prescription antifungals. BV treatment involves antibiotics.
-
Heart Attack Prevention
Heart disease and heart attacks can be prevented by leading a healthy lifestyle with diet, exercise, and stress management. Symptoms of heart attack in men and women include chest discomfort and pain in the shoulder, neck, jaw, stomach, or back.
Treatment & Diagnosis
- What is Bacterial Vaginosis?
- Drugs: Buying Prescription Drugs Online Safely
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: The Most Common Medication Errors
- Medication Disposal
- Dangers of Mixing Medications
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
Prevention & Wellness
Health News
- CDC Warns of Potentially Fatal Bacterial Illness on U.S. Gulf Coast
- Helping Others as Volunteers Helps Kids 'Flourish': Study
- FDA Approves Pfizer's RSV Shot for Older Adults
- What to Do When Tough-to-Treat Lymphoma Strikes During Pregnancy
- Rate of Pregnant U.S. Women Who Have Diabetes Keeps Rising
More Health News »
Health Solutions From Our Sponsors

Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
REFERENCE:
FDA Prescribing Information