GENERIC NAME: METRONIDAZOLE - ORAL (MET-roe-NYE-da-zole)
BRAND NAME(S): Flagyl
USES: Metronidazole is used to treat a variety of infections. It belongs to a class of antibiotics known as nitroimidazoles. It works by stopping the growth of bacteria and protozoa.This antibiotic only treats bacterial and protozoal infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.Metronidazole can also be used in combination with anti-ulcer medications to treat certain types of stomach ulcers.
HOW TO USE: This medication may be taken with food or a full glass of water or milk to prevent stomach upset. Dosage is based on your medical condition, the type of infection being treated, and your response to therapy.Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals.Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria/protozoa to continue to grow, which may result in a relapse of the infection.Inform your doctor if your condition persists or worsens.
SIDE EFFECTS: Dizziness, headache, diarrhea, nausea, stomach pain, loss of appetite, constipation, changes in taste, and dry mouth may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.This drug may cause urine to darken in color. This is harmless.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: unsteadiness, seizures, mental/mood changes (such as confusion), numbness/tingling of hands/feet, painful urination.Tell your doctor immediately if any of these rare but very serious side effects occur: eye pain, severe/persistent headache, sudden vision changes, stiff/painful neck, sore throat, persistent fever, unusual bleeding/bruising, severe stomach pain, persistent nausea/vomiting.Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Before taking metronidazole, tell your doctor or pharmacist if you are allergic to it; or to other nitroimidazoles such as tinidazole; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, nervous system disorders (e.g., seizures), blood disorders, Crohn's disease.Avoid alcoholic beverages while taking this medication and for at least 1 day (3 days if you are taking the oral capsules) after finishing this medicine because drinking alcohol may result in severe stomach upset/cramps, nausea, vomiting, headache and flushing.This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.The elderly may be at greater risk for side effects while using this drug.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.This medication passes into breast milk. Discuss the risks and benefits with your doctor before breast-feeding. If you are prescribed the single-dose treatment, your doctor may direct you to interrupt breast-feeding for a short time after the dose. Consult your doctor for more details.
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: alcohol-containing products (e.g., cough and cold syrups, aftershave), lopinavir/ritonavir oral solution, "blood thinners" (such as warfarin), busulfan, cimetidine, fluorouracil, lithium, mebendazole, live bacterial vaccines, drugs for seizures (such as phenobarbital, phenytoin).Avoid disulfiram for 2 weeks before and during treatment with this medication.Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.This medication may interfere with certain laboratory tests (including liver function tests, blood triglyceride levels), possibly causing false test results. Make sure laboratory personnel and your doctors know you use this drug.
OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include nausea, vomiting, severe dizziness, and seizures.
NOTES: Do not share this medication with others.Treatment of certain infections (trichomoniasis) may require that sexual partners be treated as well to avoid re-infection. During therapy, refrain from sexual intercourse or always use a condom.This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in those cases.Laboratory and/or medical tests (e.g., blood counts) should be performed from time to time to monitor your progress or check for side effects. Consult your doctor for more details.
MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Tablets should be stored at room temperature below 77 degrees F (25 degrees C) away from light. Capsules should be stored at or below room temperature between 59-77 degrees F (15-25 degrees C). Do not store in the bathroom. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Information last revised August 2013. Copyright(c) 2013 First Databank, Inc.
Latest MedicineNet News
Daily Health News
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Top metronidazole Related Articles
Acne (Pimples)Acne is a localized skin inflammation as a result of overactivity of oil glands at the base of hair follicles. This inflammation, depending on its location, can take the form of a superficial pustule (contains pus), a pimple, a deeper cyst, congested pores, whiteheads, or blackheads. Treatments vary depending on the severity of the acne.
Acne QuizAcne is the most common skin disorder in the world. If you suffer from acne, you are not alone and many treatment options are available. Learn more about pimples, blackheads, and comedones with the Acne Quiz.
Chronic Fatigue QuizExhausted all the time? Maybe it's not all in the mind. Take the Chronic Fatigue Syndrome (CFS) Quiz to learn more about tricky condition.
Chronic Fatigue Syndrome (CFS or SEID)Chronic fatigue syndrome (CFS) or systemic exertion intolerance disease (SEID) is a debilitating and complex disorder characterized by profound fatigue that lasts six months or longer, is not improved by bed rest, and may be worsened by physical or mental activity.
Chronic Fatigue SlidesChronic fatigue syndrome (CFS) can occur at any age for men or women. Learn more about the causes of chronic fatigue syndrome (CFS) as well as tests to diagnose extreme fatigue associated with chronic fatigue syndrome.
Clostridium Difficile Colitis (Antibiotic-Associated Colitis, C. difficile colitis)
Clostridium difficile (C. difficile) is a bacterium, and is one of the most common causes of infection of the colon. C. difficile spores are found frequently in hospitals, nursing homes, extended care facilities, and nurseries for newborn infants. They can be found:
- on bedpans,
- toilet seats,
- rooms, and
- diaper pails.
They even can be carried by pets. Antibiotic-associated (C. difficile) colitis is an infection of the colon caused by C. difficile that occurs primarily among individuals who have been using antibiotics. Treatment for C. difficile colitis includes:
- replenishment of electrolyte deficiencies,
- discontinuing the antibiotic that caused the colitis, and
- using antibiotics to eradicate the C. difficile bacterium.
Crohn's DiseaseCrohn's disease is a chronic inflammatory disease, primarily involving the small and large intestine, but which can affect other parts of the digestive system as well. Abdominal pain, diarrhea, vomiting, fever, and weight loss are common symptoms.
Crohn's Disease QuizWhat causes Crohn's disease? What are the symptoms of Crohn's disease? How is Crohn's treated? Take this quiz to get the facts about Crohn's.
Diverticulitis SlideshowDiverticulitis (diverticulosis) is a condition in which the diverticulum or diverticula rupture in the colon causing infection. Change in diet and medical treatments such as antibiotics and surgery can ease the symptoms of diverticulitis (diverticulosis).
Diverticulitis (Diverticulosis, Diverticular Disease)Most people with diverticulosis have few if any symptoms at all. When people do experience signs and symptoms of diverticulosis (diverticular disease) they may include abdominal pain, abdominal cramps, diarrhea, constipation, and bloating. Diverticulitis is a condition in which diverticuli in the colon rupture. The rupture results in infection in the tissues that surround the colon. Treatment methods for diverticulitis includes prescription medications, and in some cases, diverticulitis surgery.
Folliculitis PictureAn infection of the hair follicles of the skin. See a picture of Folliculitis and learn more about the health topic.
H. pylori (Helicobacter Pylori) InfectionHelicobacter pylori (H. pylori) is a bacteria that causes chronic inflammation (gastritis) of the inner lining of the stomach, and also is the most common cause of ulcers worldwide. About 50% of people in the world carries or is infected with H. pylori. Common symptoms of H. pylori infection are occasional abdominal discomfort, bloating, belching or burping, and nausea and vomiting. H. pylori infection is difficult to eradicate, and treatment is with two or more antibiotics.
IBD SlideshowWhat is inflammatory bowel disease? IBD can include Crohn's disease and ulcerative colitis. Learn more about testing, treatments, and the home care needed to manage inflammatory bowel disease.
Peptic Ulcer (Stomach Ulcer)Peptic or stomach ulcers are ulcers are an ulcer in the lining of the stomach, duodenum, or esophagus. Ulcer formation is related to H. pylori bacteria in the stomach, use of anti-inflammatory medications, and cigarette smoking. Symptoms of peptic or stomach ulcers include abdominal burning or hunger pain, indigestion, and abdominal discomfort after meals. Treatment for stomach ulcers depends upon the cause.
Peripheral NeuropathyPeripheral neuropathy is a problem with the functioning of the nerves outside of the spinal cord. Symptoms may include numbness, weakness, burning pain (especially at night), and loss of reflexes. Possible causes may include carpel tunnel syndrome, shingles, vitamin or nutritional deficiencies, and illnesses like diabetes, syphilis, AIDS, and kidney failure. Peripheral neuropathy is diagnosed with exams and tests. Treatment for the condition depends on the cause. Usually, the prognosis for peripheral neuropathy is good if the cause can be successfully treated or prevented.
RosaceaRosacea is a skin disease that causes redness of the forehead, chin, and lower half of the nose. In addition to inflammation of the facial skin, symptoms include dilation of the blood vessels and pimples (acne rosacea) in the middle third of the face. Oral and topical antibiotics are treatments for rosacea. If left untreated, rhinophyma (a disfiguring nose condition) may result.
SclerodermaScleroderma is an autoimmune disease of the connective tissue. It is characterized by the formation of scar tissue (fibrosis) in the skin and organs of the body, leading to thickness and firmness of involved areas. Scleroderma is also referred to as systemic sclerosis, and the cause is unknown. Treatment of scleroderma is directed toward the individual features that are most troubling to the patient.
15 Tips for Clear SkinAcne, pimples, zits and blemishes often appear on the face, back, chest, neck, and shoulders where skin has the most amount of oil glands. Few of us are immune to breakouts, but treatments can minimize outbreaks. Follow these 15 tips for a clear complexion and skin.