- High Blood Pressure Slideshow Pictures
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- What are the uses for metoprolol (Lopressor, Toprol XL)?
- Why are the uses for metoprolol (Lopressor, Toprol XL)?
- What are the side effects of metoprolol (Lopressor, Toprol XL)?
- What is the dosage for metoprolol (Lopressor, Toprol XL)?
- Which drugs or supplements interact with metoprolol (Lopressor, Toprol XL)?
- Is metoprolol (Lopressor, Toprol XL) safe to use during pregnancy or while breastfeeding?
- What else should I know about metoprolol (Lopressor, Toprol XL)?
What are the uses for metoprolol (Lopressor, Toprol XL)?
Metoprolol is a beta blocker (beta-adrenergic blocking agent) used for the treatment of:
- High blood pressure
- Heart pain
- Congestive heart failure
- Abnormal heart rhythms
- Some neurologic conditions.
Quick GuideHow to Lower Blood Pressure: Exercise Tips
Why are the uses for metoprolol (Lopressor, Toprol XL)?
- Metoprolol is used to treat:
- Metoprolol also is useful in slowing and regulating certain types of abnormally rapid heart rates (tachycardias).
- Other uses for metoprolol include:
What are the side effects of metoprolol (Lopressor, Toprol XL)?
Metoprolol is generally well tolerated. Side effects include
- abdominal cramps,
- memory loss,
- low blood pressure,
- decreased exercise tolerance,
- increased triglycerides,
- cold extremities,
- sore throat, and
- shortness of breath or wheezing.
Possible serious adverse effects include
- In patients with existing slow heart rates (bradycardias) and heart blocks (defects in the electrical conduction of the heart), metoprolol can cause dangerously slow heart rates, and even shock. Metoprolol reduces the force of heart muscle contraction and can aggravate symptoms of heart failure. In patients with coronary artery disease, abruptly stopping metoprolol can suddenly worsen angina, and occasionally precipitate heart attacks. If it is necessary to discontinue metoprolol, its dosage should be reduced gradually over several weeks.
- Initiation of high-dose extended release metoprolol in patients undergoing non-cardiac surgery is associated with bradycardia (slow heart rate), hypotension, stroke, and death. However, long-term therapy with metoprolol should not be routinely withdrawn prior to major surgery. Impaired ability of the heart to respond to reflex adrenergic stimuli may increase the risks of general anesthesia and surgery.
What is the dosage for metoprolol (Lopressor, Toprol XL)?
- Metoprolol should be taken before meals or at bedtime.
- The dose for treating hypertension is 100-450 mg daily in single or divided doses.
- Angina is treated with 100-400 mg daily in two divided doses.
- Heart attack (acute myocardial infarction) is treated with three 5 mg injections administered 2 minutes apart followed by treatment with 50 mg oral metoprolol every 6 hours for 48 hours. After 48 hours, patients should receive 100 mg orally twice daily for at least 3 months.
- The dose for congestive heart failure is 25 mg/daily initially. Then the dose is increased every 2 weeks to reach a target dose of 200 mg/daily orally.
- Hyperthyroidism is treated with 25 to 30 mg by mouth every 6 hours.
Which drugs or supplements interact with metoprolol (Lopressor, Toprol XL)?
- Calcium channel blockers and digoxin (Lanoxin) can lower blood pressure and heart rate to dangerous levels when administered together with metoprolol.
- Metoprolol can mask the early warning symptoms of low blood sugar (hypoglycemia) and should be used with caution in patients receiving treatment for diabetes.
- Fluoxetine (Prozac) can increase blood levels of metopropol by reducing breakdown of metoprolol, and increase the side effects from metoprolol.
Is metoprolol (Lopressor, Toprol XL) safe to use during pregnancy or while breastfeeding?
What else should I know about metoprolol (Lopressor, Toprol XL)?
- Metoprolol (Lopressor, Toprol XL) is available as:
- Tablets: 25, 50, and 100 mg.
- Tablets (extended release): 25, 50, 100, and 200 mg.
- Injection: 1 mg/ml
- Metoprolol (Lopressor, Toprol XL) Tablets should be stored between 15 C and 30 C (59 F and 86 F). The tablets should be protected from moisture and dispensed in tight, light-resistant containers
- Metropolol is available in the US under the brand names Lopressor and Toprol XL.
- Metropolol is avaialbe in generic form.
Metoprolol (Lopressor, Toprol XL) is a beta-adrenergic blocking agent drug, which blocks the action of the sympathetic nervous system (a portion of the involuntary nervous system). Metoprolol is prescribed to treat high blood pressure (hypertension), heart pain (angina), heart rhythm disorders, and some neurological conditions. Side effects include fever, impotence, sore throat, nausea, depression, insomnia, constipation, memory loss, and high blood pressure.
Drug interactions, dosing, and pregnancy and breastfeeding safety should be reviewed prior to taking any medication.
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Medications & Supplements
- timolol (Blocadren and Timolide 10-25 have been discontinued)
- nadolol (Corgard)
- propranolol, Inderal, Inderal LA, Innopran XL
- Sectral (acebutolol)
- atenolol, Tenormin
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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High Blood Pressure Hypertension
High blood pressure (hypertension) is a disease in which pressure within the arteries of the body is elevated. About 75 million people in the US have hypertension (1 in 3 adults), and only half of them are able to manage it. Many people do not know that they have high blood pressure because it often has no has no warning signs or symptoms.
Systolic and diastolic are the two readings in which blood pressure is measured. The American College of Cardiology released new guidelines for high blood pressure in 2017. The guidelines now state that blood normal blood pressure is 120/80 mmHg. If either one of those numbers is higher, you have high blood pressure.
The American Academy of Cardiology defines high blood pressure slightly differently. The AAC considers 130/80 mm Hg. or greater (either number) stage 1 hypertension. Stage 2 hypertension is considered 140/90 mm Hg. or greater.
If you have high blood pressure you are at risk of developing life threatening diseases like stroke and heart attack.
REFERENCE: CDC. High Blood Pressure. Updated: Nov 13, 2017.
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Hyperthyroidism is an excess of thyroid hormone due to an overactive thyroid gland. Symptoms can include increased heart rate, weight loss, heart palpitations, frequent bowel movements, depression, fatigue, fine or brittle hair, sleep problems, thinning skin, and irregular vaginal bleeding.
Graves' disease is the most common cause of hyperthyroidism. Many other health problems or taking excess thyroid hormone medication can cause an overactive thyroid gland. Treatment for the condition is with medication, radioactive iodine, thyroid surgery (rarely), or reducing the dose of thyroid hormone. No diet has been shown to treat hyperthyroidism or its symptoms and signs.
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Triggers for migraine headaches include certain foods, stress, hormonal changes, strong stimuli (loud noises), and oversleeping.
Treatment guidelines for migraines include medicine, pain management, diet changes, avoiding foods that trigger migraines, staying hydrated, getting adequate sleep, and exercising regularly. Prevention of migraine triggers include getting regular exercise, drinking water daily, reducing stress, and avoiding trigger foods.
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ParathyroidectomyParathyroidectomy is the removal of one or more of the parathyroid glands to treat hyperparathyroidism. Risks of parathyroidectomy include:
- paralysis of the vocal cords,
- difficulty swallowing thin liquids,
- difficulty breathing,
- and drug reactions.
- damage to the recurrent laryngeal nerve,
- bleeding or hematoma,
- problems maintaining calcium levels in the blood,
- need for further and more aggressive surgery,
- need for a limited or total thyroidectomy,
- prolonged pain,
- impaired healing,
- and recurrence of the tumor.
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