- Side Effects
- Drug Interactions
- Pregnancy & Breastfeeding
Brand Name: Lopressor, Toprol XL
Generic Name: metoprolol
Drug Class: Thiazide Combos
What is metoprolol (Lopressor, Toprol XL), and what is it used for?
Metoprolol is a beta-blocker (beta-adrenergic blocking agent) used for the treatment of:
- High blood pressure
- Heart pain
- Congestive heart failure
- Abnormal heart rhythms
- Some neurologic conditions.
- Metoprolol is used to treat:
- Metoprolol also is useful in slowing and regulating certain types of abnormally rapid heart rates (tachycardias).
- Other uses for metoprolol include:
What are the side effects of metoprolol (Lopressor, Toprol XL)?
Metoprolol is generally well tolerated. Side effects include:
- abdominal cramps,
- memory loss,
- low blood pressure,
- decreased exercise tolerance,
- increased triglycerides,
- cold extremities,
- sore throat, and
- shortness of breath or wheezing.
Possible serious adverse effects include:
- In patients with existing slow heart rates (bradycardias) and heart blocks (defects in the electrical conduction of the heart), metoprolol can cause dangerously slow heart rates and even shock. Metoprolol reduces the force of heart muscle contraction and can aggravate symptoms of heart failure. In patients with coronary artery disease, abruptly stopping metoprolol can suddenly worsen angina, and occasionally precipitate heart attacks. If it is necessary to discontinue metoprolol, its dosage should be reduced gradually over several weeks.
- Initiation of high-dose extended-release metoprolol in patients undergoing non-cardiac surgery is associated with bradycardia (slow heart rate), hypotension, stroke, and death. However, long-term therapy with metoprolol should not be routinely withdrawn before major surgery. The impaired ability of the heart to respond to reflex adrenergic stimuli may increase the risks of general anesthesia and surgery.
What is the dosage for metoprolol?
- Metoprolol should be taken before meals or at bedtime.
- The dose for treating hypertension is 100-450 mg daily in single or divided doses.
- Angina is treated with 100-400 mg daily in two divided doses.
- Heart attack (acute myocardial infarction) is treated with three 5 mg injections administered 2 minutes apart followed by treatment with 50 mg oral metoprolol every 6 hours for 48 hours. After 48 hours, patients should receive 100 mg orally twice daily for at least 3 months.
- The dose for congestive heart failure is 25 mg/daily initially. Then the dose is increased every 2 weeks to reach a target dose of 200 mg/daily orally.
- Hyperthyroidism is treated with 25 to 30 mg by mouth every 6 hours.
What drugs interact with metoprolol?
- Calcium channel blockers and digoxin (Lanoxin) can lower blood pressure and heart rate to dangerous levels when administered together with metoprolol.
- Metoprolol can mask the early warning symptoms of low blood sugar (hypoglycemia) and should be used with caution in patients receiving diabetes treatment.
- Fluoxetine (Prozac) can increase blood levels of metoprolol by reducing the breakdown of metoprolol and increasing the side effects of metoprolol.
Metoprolol (Lopressor, Toprol XL) is a beta-adrenergic blocking agent drug, which blocks the action of the sympathetic nervous system (a portion of the involuntary nervous system). Metoprolol is prescribed to treat high blood pressure (hypertension), heart pain (angina), heart rhythm disorders, and some neurological conditions. Side effects include fever, impotence, sore throat, nausea, depression, insomnia, constipation, memory loss, and high blood pressure.
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Related Disease Conditions
Blood Pressure Readings: Chart, Normal, High, Low
Blood pressure is the force applied by the blood over the inner walls of the arteries. Although the average blood pressure for a person remains constant, it shows minor fluctuations throughout the day—declining while relaxing and momentarily increasing while being excited or under stress. An increase in resting blood pressure can scar, stiffen, or harden the arteries.
Why Is My Bottom Blood Pressure Number High?
Isolated diastolic hypertension (IDH) occurs when your systolic blood pressure is normal, and only your diastolic blood pressure is high (over 80 mm Hg). Causes of high diastolic blood pressure include a high-sodium diet, obesity, lack of physical activity, excessive alcohol consumption, stress and anxiety.
High Blood Pressure (Hypertension)
High blood pressure (hypertension) is a disease in which pressure within the arteries of the body is elevated. About 75 million people in the US have hypertension (1 in 3 adults), and only half of them are able to manage it. Many people do not know that they have high blood pressure because it often has no has no warning signs or symptoms. Systolic and diastolic are the two readings in which blood pressure is measured. The American College of Cardiology released new guidelines for high blood pressure in 2017. The guidelines now state that blood normal blood pressure is 120/80 mmHg. If either one of those numbers is higher, you have high blood pressure. The American Academy of Cardiology defines high blood pressure slightly differently. The AAC considers 130/80 mm Hg. or greater (either number) stage 1 hypertension. Stage 2 hypertension is considered 140/90 mm Hg. or greater. If you have high blood pressure you are at risk of developing life threatening diseases like stroke and heart attack.REFERENCE: CDC. High Blood Pressure. Updated: Nov 13, 2017.
How Can I Lower My Blood Pressure in Minutes?
Learn how to lower your high blood pressure quickly and how to better manage this condition.
What Does it Mean When the Bottom Number of Your Blood Pressure is Over 100?
Diastolic blood pressure (DBP) is the pressure exerted on the walls of the arteries when the heart muscle relaxes between beats. When the bottom number of blood pressure (diastole) is over 100 mmHg, it may be called diastolic hypertension (DHT). Diastolic blood pressure means the blood pressure reading during the phase when your heart relaxes (diastole). Force of the blood against the walls of the arteries (the blood vessels carrying blood from the heart to other sites) in the body is called blood pressure. The heart pumps the blood into the arteries as it contracts (systole).
How to Lower My Blood Pressure Immediately
If you face any complications of high blood pressure such as a stroke or heart attack, contact your physician without any delay. Do not attempt home remedies in such grave situations. If you have high blood pressure, without any complications, the first thing to do is to calm down and lie flat.
What Is Considered Stroke-Level High Blood Pressure?
Blood pressure readings above 180/120 mmHg are considered stroke-level and require immediate medical attention. Check out the center below for more medical references on hypertension, including multimedia (slideshows, images, and quizzes), related diseases, treatment, diagnosis, medications, and prevention or wellness.
How Do You Check Your Blood Pressure With Fingers?
Most doctors recommend the use of a blood pressure machine to check blood pressure. An individual may check heart rate with their fingers, but not blood pressure.
Is 120 Over 60 a Good Blood Pressure Reading?
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Congestive Heart Failure (CHF)
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What Is the Blood Pressure of a Very Fit Person?
Studies show that a very fit person who exercises regularly will have a lower resting blood pressure (usually below 120/80 mm Hg) than someone who leads a sedentary lifestyle.
Arrhythmias (Abnormal Heart Rhythms)
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Atrial Fibrillation (AFib)
Atrial fibrillation (AF or AFib) is an abnormality in the heart rhythm, which involves irregular and often rapid beating of the heart. Symptoms may include heart palpitations, dizziness, fainting, fatigue, shortness of breath, and chest pain. Atrial fibrillation treatment may include medication or procedures like cardioversion or ablation to normalize the heart rate.
Hyperthyroidism is an excess of thyroid hormone due to an overactive thyroid gland. Symptoms can include increased heart rate, weight loss, heart palpitations, frequent bowel movements, depression, fatigue, fine or brittle hair, sleep problems, thinning skin, and irregular vaginal bleeding. Graves' disease is the most common cause of hyperthyroidism. Many other health problems or taking excess thyroid hormone medication can cause an overactive thyroid gland. Treatment for the condition is with medication, radioactive iodine, thyroid surgery (rarely), or reducing the dose of thyroid hormone. No diet has been shown to treat hyperthyroidism or its symptoms and signs.
Migraine headache is a type of headache associated with a sensitivity to light, smells, or sounds, eye pain, severe pounding on one side of the head, and sometimes nausea and vomiting. The exact cause of migraine headaches is not known. Triggers for migraine headaches include certain foods, stress, hormonal changes, strong stimuli (loud noises), and oversleeping. Treatment guidelines for migraines include medicine, pain management, diet changes, avoiding foods that trigger migraines, staying hydrated, getting adequate sleep, and exercising regularly. Prevention of migraine triggers include getting regular exercise, drinking water daily, reducing stress, and avoiding trigger foods.
Hypertension-Related Kidney Disease
Second Source WebMD Medical Reference
Which ACE Inhibitor Is the Best for Hypertension?
The best ACE inhibitors for hypertension include Trandolapril, Enalapril, and Ramipril.
How Is Diastolic Hypertension Treated?
Diastolic hypertension, where only your diastolic blood pressure is elevated, may be treated with lifestyle changes such as weight loss, reducing your sodium intake or alcohol consumption, and quitting smoking. Medications may be prescribed in more severe cases.
Atrial Flutter vs. Atrial Fibrillation
Atrial flutter and atrial fibrillation (AFib) are two types of a heart problem called atrial tachycardia. Both of these conditions involve the heart's electrical activity, but they are not the same disease. Both diseases are serious and need medical treatment. Common symptoms of these diseases are similar and include: Fatigue Blurry vision Lightheadedness Palpitations Feeling like you may faint Serious symptoms of both conditions are similar and include: Fainting Sweating Severe shortness of breath Chest pain Atrial flutter and AFib are heart conditions that require medical diagnosis (ECG) and treatment by a doctor or other medical health-care professional.
Heart Attack (Myocardial Infarction)
A heart attack occurs when a blood clot completely obstructs a coronary artery supplying blood to the heart muscle. Learn about warning signs, causes, complications, risk factors, and treatment.
Abdominal Aortic Aneurysm
Abdominal aortic aneurysm is a ballooning or widening of the main artery (the aorta) as it courses down through the abdomen. Most abdominal aortic aneurysms produce no symptoms. Treatment may include observation or surgical repair.
Is A Manual Blood Pressure More Accurate?
Manual blood pressure gives accurate results when used correctly by a trained person. However, manual blood pressure measurement is not the recommended type of blood pressure monitoring for home use because it requires some training.
Palpitations are uncomfortable sensations of the heart beating hard, rapidly, or irregularly. Some types of palpitations are benign, while others are more serious. Palpitations are diagnosed by taking the patient history and by performing an EKG or heart monitoring along with blood tests. An electrophysiology study may also be performed. Treatment of palpitations may include lifestyle changes, medication, ablation, or implantation of a pacemaker. The prognosis if palpitations depends on the underlying cause.
Can You Take Turmeric if You Take Blood Pressure Medicine?
Turmeric is one of the most used spices in Asian cuisine. This yellow spice has been hailed for its healing properties for centuries. A turmeric latte is touted for its myriad health benefits. Turmeric contains several anti-inflammatory compounds collectively called curcuminoids.
Which Is More Important: Systolic or Diastolic Blood Pressure?
Systolic blood pressure is often given more attention as a risk factor for heart disease. However, both systolic and diastolic blood pressure are equally important in monitoring the health of your heart.
Atrial Fibrillation (AFib) Treatment Drugs
Atrial fibrillation (AFib) is a heart rhythm disorder that causes irregular and often rapid heartbeat. The medications to treat AFib include beta-blockers, blood thinners, and heart rhythm drugs. Atrial fibrillation drugs can cause serious side effects like seizures, vision changes, shortness of breath, fainting, other abnormal heart rhythms, excessive bleeding while coughing or vomiting, blood in the stool, and bleeding into the brain.
Things to Know About High Blood Pressure Treatment
High blood pressure (hypertension) means high pressure (tension) in the arteries. Treatment for high blood pressure include lifestyle modifications (alcohol, smoking, coffee, salt, diet, exercise), drugs and medications such as ACE inhibitors, angiotensin receptor blockers, beta blockers, diuretics, calcium channel blockers (CCBs), alpha blockers, clonidine, minoxidil, and Exforge.
How Do I Know If I Have High or Low Blood Pressure Numbers?
High or low blood pressure can lead to serious health conditions. Learn more about what you should do if your pressure is outside the ideal range.
Mitral Valve Prolapse
Mitral valve prolapse (MVP), also called "click murmur syndrome" and "Barlow's syndrome," is the most common type of heart valve abnormality. Usually, people with mitral valve prolapse have no signs and symptoms; however, if the prolapsed valve is severe, symptoms may appear. When symptoms of severe mitral valve prolapse do appear, they may include, fatigue, palpitations, chest pain, anxiety, migraine headaches, and pulmonary edema. Echocardiography is the most useful test for mitral valve prolapse. Most people with mitral valve prolapse need no treatment. However, if the valve prolapse is severe, treatment medications or surgery may be necessary to repair the heart valve.
Can Drinking Water Lower Your Blood Pressure?
Keeping well hydrated by drinking six to eight glasses of water daily (even more if working in hot and humid conditions) is beneficial for the blood pressure. High blood pressure (BP) or hypertension is a condition caused by the persistent high pressure of blood against the walls of arteries. It is also called systolic pressure (constantly greater than 139 mmHg) or diastolic pressure (constantly more than 89 mmHg).
18 Ways to Lower Blood Pressure Without Medication
Lifestyle changes and home remedies are effective in controlling high blood pressure (hypertension). Check out the center below for more medical references on hypertension, including multimedia (slideshows, images, and quizzes), related disease conditions, treatment and diagnosis, medications, and prevention or wellness.
Atrial Flutter: ECG, Symptoms, and Treatments
Atrial flutter is a problem with the atria of the heart. In atrial flutter the atria of the heart rapidly and repeatedly beat due to an anomaly in the electrical system of the heart. It is a type of arrhythmia and can be dangerous because complications can develop easily. Signs and symptoms of atrial flutter include near fainting, palpitations, mild shortness of breath, and fatigue. While the exact cause of atrial flutter is not clearly understood, it's most likely related to your health, what medical conditions you certainly have, poor diet, lack of exercise, and drinking too much alcohol. Atrial flutter is diagnosed by physical examination, medical history, and a sawtooth ECG wave pattern.
What Foods Can I Eat to Lower My Blood Pressure Immediately?
What is high blood pressure and how can you lower it? Learn the best foods to help lower your blood pressure immediately.
What Are the Best Fruits for Lowering Blood Pressure?
The best fruits for lowering blood pressure include citrus fruits, berries, bananas, pomegranates, prunes, and melons.
Which Blood Pressure Number Is the Most Important?
The blood that flows through the arteries (blood vessels carrying blood from the heart to other parts of the body) exerts pressure against the arterial walls. The number above (120) is called the systolic blood pressure and the number below (80) is called the diastolic blood pressure. Though both readings are important, many doctors believe that systolic blood pressure is a better predictor of complications of hypertension, such as heart disease or stroke.
Pulmonary hypertension is elevated pressure in the pulmonary arteries that carry blood from the lungs to the heart. The most common symptoms are fatigue and difficulty breathing. If the condition goes undiagnosed, more severe symptoms may occur. As pulmonary hypertension worsens, some people with the condition have difficulty performing any activities that require physical exertion. While there is no cure for pulmonary hypertension, it can be managed and treated with medications and supplemental oxygen to increase blood oxygen levels.
Portal hypertension is most commonly caused by cirrhosis, a disease that results from scarring of the liver. Other causes of portal hypertension include blood clots in the portal vein, blockages of the veins that carry the blood from the liver to the heart, and a parasitic infection called schistosomiasis. Symptoms of portal hypertension include varices (enlarged veins), vomiting blood, blood in the stool, black and tarry stool, ascites (abnormal fluid collection within the peritoneum, the sac that contains the intestines within the abdominal cavity), confusion and lethargy, splenomegaly or enlargement of the spleen, and decreased white blood cell counts.
Hypertension-Induced Chronic Kidney Disease
Hypertension-induced chronic kidney disease (CKD) is a long-standing kidney condition that develops over time due to persistent or uncontrolled high blood pressure (hypertension).
Heart Attack Treatment
A heart attack involves damage or death of part of the heart muscle due to a blood clot. The aim of heart attack treatment is to prevent or stop this damage to the heart muscle. Heart attack treatments included medications, procedures, and surgeries to protect the heart muscle against injury.
What Are the Top Drinks to Lower Blood Pressure?
The top drinks for lowering blood pressure include beverages that are rich in nutrients and low in sodium and fats. Learn the 10 best blood-pressure-lowering drinks here.
Why Does Alcohol Cause Hypertension?
Alcoholic beverages are regular drinks in most parts of the world. No one knows how alcohol causes hypertension, but it may be due to the effects of alcohol endothelium, nervous system, cortisol levels or other body systems.
Can High Blood Pressure Hurt My Eyes?
Unfortunately, yes. Suffering from untreated or poorly controlled high blood pressure for a long time can be detrimental to your eyes. Several eye diseases are directly or indirectly caused by high blood pressure (hypertension).
Migraine vs. Headache: Differences and Similarities
Headaches are the most common reason why a person goes to the doctor or other healthcare professional for treatment. There are different types of headaches, for example, migraine, tension, and cluster headaches. The most common type of headache is tension headache. Migraine is much less common. There are few similarities between migraine and other headaches, for example, the severity of the pain can be the same, mild, moderate, or severe; and they can occur on one side or both sides of the head. However, there are many differences between migraine and other types of headaches. Migraine headaches also have different names, for example, migraine with aura and menstrual migraine. Symptoms of migraine that usually aren't experienced by a person with another type of headache include nausea, vomiting, worsens with mild exercise, debilitating pain, eye pain, throbbing head pain. Migraine trigger include light, mild exercise, strong smells, certain foods like red wine, aged cheese, smoked meats, artificial sweeteners, chocolate, alcohol, and dairy products, menstrual period, stress, oversleeping, and changes in barometric pressure. Untreated migraine attacks usually last from 4 to 72 hours, but may last for weeks. Most headaches resolve within 24-48 hours. Doctors don't know exactly what causes migraine headaches; however, other headaches like tension headaches have more specific triggers and causes. Additional tests usually are required to diagnose migraine from other types of headaches, diseases, or other medical problems. Most headaches can be treated and cured with home remedies like essential oils, massage, and over-the-counter pain medication like acetaminophen (Tylenol) and NSAIDs (nonsteroidal anti-inflammatory drugs) like naproxen (Aleve, Anaprox, Naprosyn) or ibuprofen (Advil, Midol, Motrin). Most headaches resolve with OTC and home remedy treatment, while your doctor may need to prescribe medication to treat your migraines. If you have the "worst headache of your life," seek medical care immediately.
What Can I Eat To Lower My Blood Pressure Immediately?
Learn what you can eat to lower your blood pressure to a more healthy level and help you manage hypertension.
What Is Normal Blood Pressure by Age?
What is normal blood pressure? Learn about normal blood pressure by age and the risk factors of hypertension.
What Are the Signs Your Blood Pressure Is Too High?
What is high blood pressure, and how do you lower it? Learn the signs of high blood pressure and what to do if your blood pressure numbers go above a healthy range.
What Are Abnormal Blood Pressure Number Ranges?
Abnormal blood pressure, especially high blood pressure, is a common issue with no initial symptoms. Learn how to keep your blood pressure in the normal range.
What Is Aortic Dissection?
Aortic dissection is a small tear in the large blood vessel that leads from the heart and supplies blood to the body. Symptoms of aortic dissection include a tearing or ripping pain, nausea, sweating, weakness, shortness of breath, sweating, or fainting. Treatment depends on the type of aortic dissection, and the severity of the tear in the aorta.
Can I Check My Blood Pressure With My Phone?
The force of the blood against the walls of the blood vessels carrying blood from the heart to other sites in the body (the arteries) is called blood pressure. The heart pumps blood into the arteries as it contracts (systole).
What Will Happen if Your Blood Pressure is Too High?
High blood pressure, also known as hypertension, can have negative consequences on your health. Learn what happens if your blood pressure is too high, the causes of high blood pressure, and what you can do to treat it.
Heart Attack Prevention
Heart disease and heart attacks can be prevented by leading a healthy lifestyle with diet, exercise, and stress management. Symptoms of heart attack in men and women include chest discomfort and pain in the shoulder, neck, jaw, stomach, or back.
What Are the New Blood Pressure Guidelines for Seniors?
Hypertension or high blood pressure (high BP) is a medical condition where the pressure in the blood vessels is persistently elevated. The heart pumps blood into the arteries, which circulate blood to all parts of the body. In cases of high blood pressure, the heart has to work harder to push the blood column ahead.
What Is High Blood Pressure (Hypertension)?
High blood pressure or hypertension is when the blood pressure readings consistently range from 140 or higher for systolic or 90 or higher for diastolic. Blood pressure readings above 180/120 mmHg are dangerously high and require immediate medical attention.
Is Pseudotumor Cerebri the Same as Intracranial Hypertension?
Pseudotumor cerebri (PTC) is also called idiopathic intracranial hypertension (IIH). The condition causes symptoms similar to a brain tumor.
What Is “Normal” Blood Pressure?
Normal blood pressure is when the pressure is less than or upto 120/80 mmHg. The value 120 denotes the systolic pressure, and the value 80 denotes the diastolic pressure.
What Can You Do For Treatment if Your Blood Pressure Is Too Low?
Learn what medical treatments can help with your low blood pressure and speed up your recovery.
High Blood Pressure Symptoms
Most people with high blood pressure have no signs or symptoms, even if blood pressure readings reach dangerously high levels. In some patients, symptoms may include fatigue, headaches, dizziness, confusion, sweating, chest pain and vision problems.
How Does High Blood Pressure Affect Pregnancy?
High blood pressure during pregnancy can cause serious complications. Learn more about the signs of and risks associated with the condition.
What Is the Proper Way to Take Your Blood Pressure?
Nowadays, you can easily measure your blood pressure at home using an automated blood pressure machine or sphygmomanometer. Here’s how to do it step-by-step to make sure you’re doing it the right way.
Treatment & Diagnosis
- High Blood Pressure (Hypertension)
- Enlarged Heart
- Pregnancy-Induced Hypertension
- Atrial Fibrillation (AFib)
- Aortic Dissection
- Pulmonary Hypertension
- Mitral Valve Prolapse
- Heart Disease
- Portal Hypertension
- Doctor: Checklist to Take To Your Doctor's Appointment
- Heart Failure
- High Blood Pressure FAQs
- Heart Disease FAQs
- Thyroid FAQs
- Salt FAQs
- Atrial Fibrillation A-Fib FAQs
- Heart Failure FAQs
- High Blood Pressure Symptoms
- Medication Disposal
- Dangers of Mixing Medications
- Hypertension In The Elderly - Deserves More Attention
- How To Reduce Your Medication Costs
- Salt, DASH, High Blood Pressure
- Pharmacy Visit, How To Get The Most Out of Your Visit
- High Blood Pressure and Exercise
- Indications for Drugs: Approved vs. Non-approved
- Beta Blockers: Why Take a Beta Blocker?
- High Blood Pressure: Questions To Ask Your Doctor
- Inherited High Blood Pressure in a Teenager
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- What Does Hypertension Urgency Mean?
- Does Menopause Cause High Blood Pressure?
- Can I Lift Weights with High Blood Pressure?
- Pain Relievers and High Blood Pressure
- Generic Drugs, Are They as Good as Brand-Names?
- Heart Healthy Diet: Hypertension & Heart Disease
- High Blood Pressure: Improve Your Lifestyle
Medications & Supplements
- Drugs: Questions to Ask Your Doctor or Pharmacist about Your Drugs
- Beta Blockers
- Drug Interactions
- Types of High Blood Pressure Medications
- Beta Blocker Side Effects (Adverse Effects)
- propranolol, Inderal, Inderal LA, Innopran XL
- Congestive Heart Failure Medications
- bisoprolol (Zebeta)
- Side Effects of Lopressor (metoprolol)
- erenumab (Aimovig)
- timolol ophthalmic solution (Timoptic)
- bisoprolol and hydrochlorothiazide (Ziac)
- nadolol (Corgard)
- timolol (Betimol)
- Sectral (acebutolol)
Prevention & Wellness
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.