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- What are the uses for metoprolol (Lopressor, Toprol XL)?
- Why are the uses for metoprolol (Lopressor, Toprol XL)?
- What are the side effects of metoprolol (Lopressor, Toprol XL)?
- What is the dosage for metoprolol (Lopressor, Toprol XL)?
- Which drugs or supplements interact with metoprolol (Lopressor, Toprol XL)?
- Is metoprolol (Lopressor, Toprol XL) safe to use during pregnancy or while breastfeeding?
- What else should I know about metoprolol (Lopressor, Toprol XL)?
What are the uses for metoprolol (Lopressor, Toprol XL)?
Metoprolol is a beta blocker (beta-adrenergic blocking agent) used for the treatment of:
- High blood pressure
- Heart pain
- Congestive heart failure
- Abnormal heart rhythms
- Some neurologic conditions.
Why are the uses for metoprolol (Lopressor, Toprol XL)?
- Metoprolol is used to treat:
- Metoprolol also is useful in slowing and regulating certain types of abnormally rapid heart rates (tachycardias).
- Other uses for metoprolol include:
What are the side effects of metoprolol (Lopressor, Toprol XL)?
Metoprolol is generally well tolerated. Side effects include
- abdominal cramps,
- memory loss,
- low blood pressure,
- decreased exercise tolerance,
- increased triglycerides,
- cold extremities,
- sore throat, and
- shortness of breath or wheezing.
Possible serious adverse effects include
- In patients with existing slow heart rates (bradycardias) and heart blocks (defects in the electrical conduction of the heart), metoprolol can cause dangerously slow heart rates, and even shock. Metoprolol reduces the force of heart muscle contraction and can aggravate symptoms of heart failure. In patients with coronary artery disease, abruptly stopping metoprolol can suddenly worsen angina, and occasionally precipitate heart attacks. If it is necessary to discontinue metoprolol, its dosage should be reduced gradually over several weeks.
- Initiation of high-dose extended release metoprolol in patients undergoing non-cardiac surgery is associated with bradycardia (slow heart rate), hypotension, stroke, and death. However, long-term therapy with metoprolol should not be routinely withdrawn prior to major surgery. Impaired ability of the heart to respond to reflex adrenergic stimuli may increase the risks of general anesthesia and surgery.
What is the dosage for metoprolol (Lopressor, Toprol XL)?
- Metoprolol should be taken before meals or at bedtime.
- The dose for treating hypertension is 100-450 mg daily in single or divided doses.
- Angina is treated with 100-400 mg daily in two divided doses.
- Heart attack (acute myocardial infarction) is treated with three 5 mg injections administered 2 minutes apart followed by treatment with 50 mg oral metoprolol every 6 hours for 48 hours. After 48 hours, patients should receive 100 mg orally twice daily for at least 3 months.
- The dose for congestive heart failure is 25 mg/daily initially. Then the dose is increased every 2 weeks to reach a target dose of 200 mg/daily orally.
- Hyperthyroidism is treated with 25 to 30 mg by mouth every 6 hours.
Which drugs or supplements interact with metoprolol (Lopressor, Toprol XL)?
- Calcium channel blockers and digoxin (Lanoxin) can lower blood pressure and heart rate to dangerous levels when administered together with metoprolol.
- Metoprolol can mask the early warning symptoms of low blood sugar (hypoglycemia) and should be used with caution in patients receiving treatment for diabetes.
- Fluoxetine (Prozac) can increase blood levels of metopropol by reducing breakdown of metoprolol, and increase the side effects from metoprolol.
Quick GuideHow to Lower Blood Pressure: Exercise Tips
Is metoprolol (Lopressor, Toprol XL) safe to use during pregnancy or while breastfeeding?
What else should I know about metoprolol (Lopressor, Toprol XL)?
- Metoprolol (Lopressor, Toprol XL) is available as:
- Tablets: 25, 50, and 100 mg.
- Tablets (extended release): 25, 50, 100, and 200 mg.
- Injection: 1 mg/ml
- Metoprolol (Lopressor, Toprol XL) Tablets should be stored between 15 C and 30 C (59 F and 86 F). The tablets should be protected from moisture and dispensed in tight, light-resistant containers
- Metropolol is available in the US under the brand names Lopressor and Toprol XL.
- Metropolol is available in generic form.
Heart Health Resources
Metoprolol (Lopressor, Toprol XL) is a beta-adrenergic blocking agent drug, which blocks the action of the sympathetic nervous system (a portion of the involuntary nervous system). Metoprolol is prescribed to treat high blood pressure (hypertension), heart pain (angina), heart rhythm disorders, and some neurological conditions. Side effects include fever, impotence, sore throat, nausea, depression, insomnia, constipation, memory loss, and high blood pressure.
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- High Blood Pressure FAQs
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- Salt FAQs
- Atrial Fibrillation A-Fib FAQs
- Heart Failure FAQs
- Dangers of Mixing Medications
- Medication Disposal
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Beta Blockers: Why Take a Beta Blocker?
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
- timolol (Blocadren and Timolide 10-25 have been discontinued)
- nadolol (Corgard)
- propranolol, Inderal, Inderal LA, Innopran XL
- Sectral (acebutolol)
- atenolol, Tenormin
- bisoprolol and hydrochlorothiazide, Ziac
- bisoprolol, Zebeta
- timolol ophthalmic solution (Timoptic, Timoptic-XE, Timoptic in Ocudose)
- Beta Blockers (Drug Class, List of Brand and Generic Names)
- Drugs: Questions to Ask Your Doctor or Pharmacist about Your Drugs
- Drug Interactions
- High Blood Pressure Drugs (Hypertension)
- Congestive Heart Failure Medications
- Beta Blocker Side Effects (Adverse Effects)
- erenumab (Aimovig)
Prevention & Wellness
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- Do Angioplasty Patients Really Need Beta-Blocker Drugs?
- Prescription Drug Use on the Rise in U.S.
- Some Blood Pressure Drugs May Be Risky for Certain Surgery Patients
- Study: Lowering Beta-Blocker Dose May Boost Survival After Heart Attack
- Blood Pressure Drugs Linked to Longer Ovarian Cancer Survival
- Drugs Can Sometimes Prevent Migraines, but at a Cost
- Melatonin May Improve Sleep for People on Blood-Pressure Meds
- 2 Common Blood Pressure Meds Fare Equally in Preventing Heart Woes
- Migraine Guidelines Focus on Prevention
- Drug Approved to Treat High Blood Pressure
- Prescription Meds Can Put on Unwanted Pounds
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