Methylsulfonylmethane (MSM) is also called dimethyl sulfone, DMSO2, methyl sulfone, and many other names. MSM is an organic sulfur found in fruits, vegetables, grains, and milk as well as the urine of animals. It is an oxidation product of dimethyl sulfoxide (DMSO) and a source of sulfur for producing the amino acids methionine and cysteine. MSM is a water soluble white, odorless, crystalline compound that contains 34% elemental sulfur.

Methylsulfonylmethane reduces pain, inflammation, and allergic reactions. It also has wound healing, dermatologic, and exercise performance increasing effects.

MSM has many uses. It is possibly effective for treating osteoarthritis, hemorrhoids, and rosacea, and may reduce the risk of developing exercise related muscle damage.

It also is used to treat:

• Chronic pain
• Joint inflammation
• Rheumatoid arthritis
• Bursitis
• Tendonitis
• Tenosynovitis
• Muscle cramps
• Stretch marks
• Hair loss
• Wrinkles
• Eye inflammation
• Wounds
• Allergies
• Gum disease
• Many other conditions

Common side effects associated with MSM include:

• Diarrhea
• Abdominal discomfort
• Nausea

Other side effects include:

• Swelling
• Fatigue
• Difficulty concentrating
• Insomnia
• Headache

• Typical doses adult dosages range from 500 to 8,000 mg.
• MSM supplements may be taken daily with or after meals.

There are no drug interactions listed for methylsulfonylmethane.

• Use of MSM during pregnancy has not been adequately evaluated.
• It is not known whether MSM is excreted in breast milk.

Doctor's Best MSM, Natures Way MSM, and Now Foods MSM are brand names available for MSM.

What preparations of methylsulfonylmethane (MSM) are available?

• Methylsulfonylmethane is available as tablets and powder, and is a component of many herbal products.

How should I keep methylsulfonylmethane (MSM) stored?

• Methylsulfonylmethane should be stored at room temperature, 20 C to 25 C (68 F to 77 F).

MSM and other herbal supplements are not approved by the FDA for the prevention or treatment medical diseases or conditions. Talk with your doctor or other health care professional, or a pharmacist before using this product.