- Side Effects
- Drug Interactions
- Preparation & Storage
What is melatonin, and how does it work (mechanism of action)?
Melatonin is a natural hormone produced by the pineal gland in the body. Commercially available melatonin that is sold as medicine is produced in the laboratory. Melatonin regulates the sleep-wake cycle. Check with your healthcare professional before using herbs or other supplements.
Melatonin is also used for the treatment of:
What brand names are available for melatonin?
Is melatonin available as a generic drug?
Do I need a prescription for melatonin?
What is the dosage for melatonin?
Which drugs or supplements interact with melatonin?
Melatonin should be used with caution with medications like:
- zolpidem (Ambien),
- alprazolam (Xanax),
- clonazepam (Klonopin),
- diazepam (Valium), and
- zalepon (Sonata).
These drugs cause increased sedation.
Melatonin should be used with caution with medications like:
- warfarin (Coumadin),
- clopidogrel (Plavix),
- diclofenax (Voltaren), and
- meloxicam (Mobic).
These drugs increase the risk of bleeding and bruising.
Is melatonin safe to take if I'm pregnant or breastfeeding?
What else should I know about melatonin?
What preparations of melatonin-oral are available?
- Melatonin is available in 1 mg, 3 mg, 5 mg, and 10 mg strengths.
- Melatonin is available in tablets, capsules, chewable gummies, sublingual tablets, and in liquid form.
How should I keep melatonin-oral stored?
- Melatonin is usually stored at room temperature.
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Medscape: Melatonin (Herbs/Suppl) N-acetyl-5-methoxytryptamine, pineal hormone
Medline Plus, National Library of Medicine