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- What is mebendazole chewable, and how does it work (mechanism of action)?
- What are the side effects of mebendazole chewable?
- What is the dosage for mebendazole chewable?
- Which drugs or supplements interact with mebendazole chewable?
- Is mebendazole chewable safe to take if I'm pregnant or breastfeeding?
- What else should I know about mebendazole chewable?
What is mebendazole chewable, and how does it work (mechanism of action)?
Mebendazole is a member of the benzimidazole class of antiparasitic agents, which also includes thiabendazole, albendazole, and triclabendazole. Mebendazole, like other benzimidazoles, causes death of parasites by interfering with the function of tubulin, an important protein in parasites, and preventing glucose uptake. Mebendazole is active against tapeworms, roundworms, hookworms, threadworms, pinworms, pork worms, and whipworms. The FDA approved mebendazole in June 1974.
Is mebendazole chewable available as a generic drug?
Do I need a prescription for mebendazole chewable?
What are the side effects of mebendazole chewable?
Mebendazole may cause:
What is the dosage for mebendazole chewable?
Recommendations are based on the infecting organism being treated.
Which drugs or supplements interact with mebendazole chewable?
- Mebendazole should not be used with metronidazole (Flagyl) due to the increased risk of rare but serious life-threatening skin conditions known as Stevens-Johnson syndrome and toxic epidermal necrolysis.
- Carbamazepine (Tegretol, Tegretol SR, Equetro, Carbatrol), fosphenytoin (Cerebyx), ethotoin (Peganone), and phenytoin (Dilantin, Dilantin-125) may interfere with successful treatment with mebendazole by decreasing its blood levels.
- Cimetidine (Tagamet) may increase mebendazole levels and increase the risk of side effects from mebendazole.
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Is mebendazole chewable safe to take if I'm pregnant or breastfeeding?
Adverse outcomes in animal studies have been observed. Adverse outcomes in human pregnancy have not been seen, however the Centers for Disease Control recommends postponing pinworm therapy until the third trimester when possible.
NURSING MOTHERS: While excretion into breast milk is unlikely, caution should be used since data is not available on excretion of mebendazole into breast milk.
What else should I know about mebendazole chewable?
What preparations of mebendazole chewable are available?
Chewable tablets: 100 mg
How should I keep mebendazole chewable stored?
Mebendazole should be protected from light and stored at room temperature, between 15 C to 30 C (59 F to 86 F).
Mebendazole (Vermox, discontinued) is a medication prescribed to treat pork worms, tapeworms, roundworms, hookworms, threadworms, pinworms, and whipworms. Side effects, drug interactions, dosage, and pregnancy safety information should be reviewed prior to taking this medication.
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Related Disease Conditions
Pinworms (Infection in Children and Adults, Enterobiasis)
Pinworm infection is an intestinal infection caused by a pinworm, seatworm, or threadworm. Female pinworms leave the intestine through the ankus and deposit eggs on the skin around the anus while a person is asleep. Pinworm infection is the most common worm infection in the U.S. Symptoms include anal itching or vaginal itching. Pinworm infection is generally spread by inadequate handwashing from infected persons. Treatment is effective after a diagnosis is made with a pinworm test.
Trichinosis Worm Infection
Trichinosis is a food-borne disease caused by ingesting parasites (roundworms) in undercooked pork or wild-game meat. Symptoms of trichinosis include diarrhea, nausea, muscle aches, itching, fever, chills, and joint pains.Trichinosis usually resolves without treatment, but more severe cases are treated with thiabendazole (Mintezol), albendazole (Abenza), or mebendazole (Vermox).
Colitis refers to inflammation of the inner lining of the colon. Symptoms of the inflammation of the colon lining include diarrhea, pain, and blood in the stool. There are several causes of colitis, including infection, ischemia of the colon, inflammatory bowel disease (Crohn's disease, ulcerative colitis, infectious colitis like C. difficile, or microscopic colitis). Treatment depends on the cause of the colitis.
A parasite names Ascaris lumbricoides causes ascariasis. Symptoms and signs include abdominal pain, abdominal swelling, nausea, vomiting, fever, and passage of parasites and eggs in stool. Treatment involves taking oral medications for one to three days.
Giardiasis (Giardia lamblia) is a parasite responsible for a common form of infectious diarrhea. The parasite lives in two stages: trophozoites and cysts. People at risk for giardiasis are those that live in areas where there is inadequate sanitation or treatment of drinking water. Giardiasis also is a common cause of outbreaks of diarrhea in day-care centers. Symptoms of giardiasis include abdominal pain, stomach cramping, bloating, nausea, and fatigue. Treatment for giardiasis is with antibiotic medication.
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