How Does Mixed Connective Tissue Disease (MCTD) Affect Pregnancy?

Ask the experts

I would like information on MCTD effects with pregnancy.

Doctor's response

Some patients with MCTD (Mixed Connective Tissue Disease) can have difficulty becoming pregnant (decreased fertility). There is also some increased risk of miscarriage in pregnant women with MCTD. Pregnant women with MCTD can have worsening (increased activity) of their disease during pregnancy. I am unaware of any reports of birth defects or other direct effects on the baby of mothers with MCTD.

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Last Editorial Review: 1/11/2018