Mantle Cell Lymphoma: Symptoms & Signs

Mantle cell lymphoma is a type of cancer of the B lymphocytes of the immune system. These cells are typically found in the mantle, or outer rim, of the lymph node follicle.

Signs and symptoms of mantle cell lymphoma can include

• loss of appetite,
• weight loss,
• fever,
• night sweats,
• nausea or vomiting, and
• swollen lymph nodes in the neck, armpits, or groin.

Other associated signs and symptoms can include

• heartburn,
• abdominal pain,
• abdominal bloating,
• a sense of fullness or discomfort from enlarged liver or spleen,
• pressure or pain in the lower back, and
• fatigue.

Cause of mantle cell lymphoma

The exact cause of mantle cell lymphoma is unknown. Around 85% of people with the condition have a genetic abnormality known as a translocation, resulting in the overproduction of cyclin D1, a protein that drives cell growth.

Other mantle cell lymphoma symptoms and signs

• Abdominal Bloating
• Abdominal Pain
• Fatigue
• Fever
• Heartburn
• Loss of Appetite
• Nausea or Vomiting
• Night Sweats
• Pressure or Pain in the Lower Back
• A Sense of Fullness or Discomfort from Enlarged Liver or Spleen
• Swollen Lymph Nodes in the Neck, Armpits, or Groin
• Weight Loss