Mantle Cell Lymphoma: Symptoms & Signs

Medically Reviewed on 9/17/2021

Mantle cell lymphoma is a type of cancer of the B lymphocytes of the immune system. These cells are typically found in the mantle, or outer rim, of the lymph node follicle.

Signs and symptoms of mantle cell lymphoma can include

Other associated signs and symptoms can include

Cause of mantle cell lymphoma

The exact cause of mantle cell lymphoma is unknown. Around 85% of people with the condition have a genetic abnormality known as a translocation, resulting in the overproduction of cyclin D1, a protein that drives cell growth.

Other mantle cell lymphoma symptoms and signs


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Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.