Reviewed on 6/11/2021
Other Name(s):

Brunfelsia hopeana, Brunfelsia uniflora, Brunfelsie Pauciflore, Hier-Aujourd'hui-Demain, Mercure Végétal, Pohl, Vegetable Mercury.


Manaca is a plant. The root is used to make medicine.

People take manaca for arthritis and fluid retention.

How does it work?

There isn't enough information to know how manaca might work.


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Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

  • Arthritis.
  • Fluid retention.
  • Other conditions.
More evidence is needed to rate the effectiveness of manaca for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

There isn't enough information to know if manaca is safe for people to use. In animals, manaca can cause anxiety, restlessness, increases in heart and breathing rates, drooling, vomiting, muscle spasms, and death.


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Special Precautions & Warnings

Pregnancy and breast-feeding: Not enough is known about the use of manaca during pregnancy and breast-feeding. Stay on the safe side and avoid use.


The appropriate dose of manaca depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for manaca. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.