malathion (Ovide)

• Malathion is a pesticide used for killing head lice (Pediculus humanus capitis). It kills head lice and lice eggs by blocking the activity of enzymes (cholinesterase) that breaks-down and inactivates acetylcholine (a neurotransmitter) in head lice. This causes high levels of acetylcholine which leads to death of lice.
• The FDA approved malathion in August, 1982.

What brand names are available for malathion?

Ovide

Is malathion available as a generic drug?

Yes

Do I need a prescription for malathion?

Yes

• Malathion is used for treating people who have head lice and their eggs (Pediculus humanus capitis).

Common side effects of malathion include:

• Skin irritation
• Scalp irritation
• Other side effects include:
• Mild conjunctivitis from accidental eye contact
• Possible serious side effects include:
• Chemical burn (second degree burn)

Malathion is flammable

1. Dry hair and scalp should be thoroughly wet with malathion lotion, including the back of the head and neck. The hands should be washed after applying.
2. The hair should not be covered and should dry naturally without using an electric heat source.
3. The hair should be shampooed after 8 to 12 hours, rinsed and combed with a fine - toothed (nit) comb to remove dead lice and eggs.
4. Malathion lotion should be applied again if lice are still present after 7 - 9 days.

• There are no drug interactions listed for malathion.

• Malathion has not been adequately evaluated in pregnant women. Available data from animals suggests that the risk of fetal toxicity is low. It should be used (or handled) during pregnancy only if clearly needed.
• It is not known whether malathion is excreted in breast milk.

What preparations of malathion are available?

• Lotion: 0.5%

How should I keep malathion stored?

• Malathion should be stored at room temperature, 20 C - 25 C (68 F - 77 F). It is flammable and should be kept away from heat and open flame.