- What other names is Madder known by?
- What is Madder?
- How does Madder work?
- Are there safety concerns?
- Dosing considerations for Madder.
Bengal Madder, Dyer's Madder, Fäberröte, Garança, Garance, Garance des Teinturiers, Granza, Indian Madder, Krapp, Robbia, Rouge des Teinturiers, Rubia, Rubia de Tintas, Rubia tinctorum, Rubiae Tinctorum Radix.
Madder is a plant. The root is used to make medicine.
Despite serious safety concerns, people take madder by mouth for preventing and dissolving kidney stones, as well as and for treating general menstrual disorders, and urinary tract disorders, blood disorders, bruises, jaundice, paralysis, spleen disorders, and sciatica. It is also used to promote urination, as an aphrodiasiac, and as a tonic.
Insufficient Evidence to Rate Effectiveness for...
- Kidney stones.
- Menstrual problems.
- Urinary problems.
- Blood disorders.
- Spleen disorders.
- Pain along the sciatic nerve (sciatica).
- Wound healing.
- Other conditions.
Some chemicals in madder might help prevent kidney stones. The chemical in madder known as alizarin might block a protein that is needed by the HIV virus to replicate.
Special Precautions & Warnings:Pregnancy and breast-feeding: It's UNSAFE to take madder by mouth if you are pregnant. It might start your menstrual period and that could cause a miscarriage. Madder might also cause birth defects.
It's also UNSAFE to use madder if you are breast-feeding. It might harm the nursing baby, and it might turn breast milk red.
The appropriate dose of madder depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for madder. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
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Boldizsár I, Szucs Z, Füzfai Z, Molnár-Perl I. Identification and quantification of the constituents of madder root by gas chromatography and high-performance liquid chromatography. J Chromatogr A 2006;1133(1-2):259-74. View abstract.
Brinkworth RI, Fairlie DP. Hydroxyquinones are competitive non-peptide inhibitors of HIV-1 proteinase. Biochim Biophys Acta 1995;1253(1):5-8.View abstract.
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Myers HM. Alizarin and tetracycline binding by bone mineral. Am J Phys Anthropol 1968;29(2):179-182. View abstract.
Norton SA. Useful plants of dermatology. IV. Alizarin red and madder. J Am Acad Dermatol 1998;39(3):484-485. View abstract.
Poginsky B, Westendorf J, Blomeke B, et al. Evaluation of DNA-binding activity of hydroxyanthraquinones occurring in Rubia tinctorum L. Carcinogenesis 1991;12(7):1265-1271. View abstract.
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Westendorf J, Pfau W, Schulte A. Carcinogenicity and DNA adduct formation observed in ACI rats after long-term treatment with madder root, Rubia tinctorum L. Carcinogenesis 1998;19:2163-8. View abstract.
Westendorf J, Poginsky B, Marquardt H, Groth G, Marquardt H. The genotoxicity of lucidin, a natural component of Rubia tinctorum L., and lucidinethylether, a component of ethanolic Rubia extracts. Cell Biol Toxicol 1988;4(2):225-239.View abstract.