Lymphocytic Colitis: Symptoms & Signs

Medically Reviewed on 1/29/2020

Lymphocytic colitis is an inflammation of the large intestine (colon). An accumulation of a type of inflammatory cells known as lymphocytes in the wall of the intestine characterizes lymphocytic colitis. Lymphocytic colitis is a microscopic colitis, meaning that a medical professional can only see the inflammation in the intestine when examining a tissue sample under a microscope.

Signs and symptoms of lymphocytic colitis can include

Loss of control over bowel movements is another possible associated sign.

Cause of a lymphocytic colitis

Doctors do not understand the exact cause of lymphocytic colitis. It may be due to an abnormal immune response against certain bacteria, foods, or environmental substances like pollen. Certain medications can also cause lymphocytic colitis.

Other lymphocytic colitis symptoms and signs


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Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.