Testosterone is a natural hormone produced by the testes in men; it is also produced in small amounts by the ovaries in women. Having low levels of testosterone is a condition that has been described in both men and women. Low testosterone levels can be caused by problems with the testes and ovaries themselves or conditions that affect the pituitary gland and hypothalamus of the brain. Aging is also a known cause of low testosterone in men, and obesity can also lower testosterone levels.
Symptoms of low testosterone in men can include
- erectile dysfunction (ED),
- decreased libido (low sex drive), and
- infertility.
Men with low T can also show a loss of muscle mass, hair loss, and low bone density (osteoporosis). Increased body fat, depression, mood changes, lack of energy, and sleep disturbances have also been linked with low levels of testosterone. If low T occurs prior to puberty, sexual maturation can be affected. Symptoms of low testosterone in women can include
- a decrease in libido,
- hot flashes,
- irritability,
- sleep disturbances,
- loss of muscle mass,
- loss of body hair,
- osteoporosis.
Other causes of low testosterone (low t)
- Abnormal Pituitary Development
- Aging
- Certain Medications (Including Some Cancer Chemotherapy, Hormones, and Opiate Pain Medications)
- Chronic Kidney Disease
- Hormonal Disorders
- Kallmann Syndrome
- Pituitary Tumor
- Primary Hypogonadism
- Radiation Therapy
- Trauma or Injury to the Testes
- Undescended Testicles
Main Article on Low Testosterone (Low T)

SLIDESHOW
Low Testosterone (Low T) Treatments See SlideshowPictures, Images, Illustrations & Quizzes
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Erectile Dysfunction (ED) Causes and Treatment
Having erection problems? What is erectile dysfunction (ED)? Learn about erectile dysfunction causes and treatments such as drugs...
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Erectile Dysfunction (Impotence) Quiz: Causes & Treatment
Did you know that certain medical condition may be responsible for ED? Some causes of impotence are medically treatable and...
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Low Testosterone (Low T) Quiz: Test Your IQ of Men's Conditions
What are symptoms of low testosterone (low T)? Take this quiz to learn more about causes of low testosterone and how to treat it.
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Low Testosterone (Low T) Treatments
What causes low testosterone (low T)? Learn about low testosterone symptoms in men. Discover low testosterone treatment and the...
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Sex-Drive Killers: The Causes of Low Libido
Noticing a lack of intimacy with your partner? Here we explore how stress, lack of sleep, weight gain, depression and low T can...
Causes of Low Testosterone (Low T)
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AIDS (Acquired Immunodeficiency Syndrome)
AIDS is the advanced stage of HIV infection. Symptoms and signs of AIDS include pneumonia due to Pneumocystis jiroveci, tuberculosis, toxoplasmosis, seizures, weakness, meningitis, yeast infection of the esophagus, and Kaposi's sarcoma. Anti-retroviral therapy (HAART) is used in the treatment of AIDS.
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Brain and Spinal Cord Tumors in Adults
Brain and spinal tumors are diseases in which cancer (malignant) cells begin to grow in the tissues of the brain. Tumors that start in the brain are called primary brain tumors. Tumors that start in the brain and spread to other organs are called primary brain tumors. Symptoms and signs may include headaches, personality changes, dizziness, and trouble walking. Treatment depends upon the type and grade of the tumor.
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Brain Tumors
A brain tumor can be either non-cancerous (benign) or cancerous (malignant), primary, or secondary. Common symptoms of a primary brain tumor are headaches, seizures, memory problems, personality changes, and nausea and vomiting. Causes and risk factors include age, gender, family history, and exposure to chemicals. Treatment is depends upon the tumor type, grade, and location.
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Diabetes (Type 1 and Type 2)
Diabetes is a chronic condition characterized by high levels of sugar (glucose) in the blood. The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin dependent). Symptoms of diabetes include increased urine output, thirst, hunger, and fatigue. Treatment of diabetes depends on the type.
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Hemochromatosis (Iron Overload)
Hereditary hemochromatosis (iron overload) is an inherited disorder in which there is excessive accumulation of iron in the body. Individuals may have no symptoms or signs, or they can have severe symptoms and signs of iron overload. The most effective treatment for hemochromatosis is therapeutic phlebotomy.
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How Can a Man Tell if He Has a Hormonal Imbalance?
What is a hormonal imbalance? Learn the signs of hormonal imbalance in men and what to do if you suspect you have a hormonal imbalance.
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How Does Exercise Affect Testosterone Levels?
Over a long period of time, exercise has been found to increase testosterone levels in men. However, even over the short term, exercise has been found to have effects.
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Human Immunodeficiency Virus (HIV)
HIV (human immunodeficiency virus) infection left untreated causes AIDS (acquired immunodeficiency syndrome). The human immunodeficiency virus (HIV) is a type of virus called a retrovirus, which can infect humans when it comes in contact with tissues that line the vagina, anal area, mouth, or eyes, or through a break in the skin. HIV infection is generally a slowly progressive disease in which the virus is present throughout the body at all stages of the disease. Three stages of HIV infection have been described. The initial stage of infection (primary infection), which occurs within weeks of acquiring the virus, often is characterized by the flu- or mono-like illness that generally resolves within weeks. The stage of chronic asymptomatic infection (meaning a long duration of infection without symptoms) lasts an average of eight to 10 years without treatment. The stage of symptomatic infection, in which the body's immune (or defense) system has been suppressed and complications have developed, is called the acquired immunodeficiency syndrome (AIDS). The symptoms are caused by the complications of AIDS, which include one or more unusual infections or cancers, severe loss of weight, and intellectual deterioration (called dementia). When HIV grows (that is, by reproducing itself), it acquires the ability to change (mutate) its own structure. These mutations enable the virus to become resistant to previously effective drug therapy. The goals of drug therapy are to prevent damage to the immune system by the HIV virus and to halt or delay the progress of the infection to symptomatic disease. Therapy for HIV includes combinations of drugs that decrease the growth of the virus to such an extent that the treatment prevents or markedly delays the development of viral resistance to the drugs. The best combination of drugs for HIV are those that effectively suppress viral replication in the blood and also are well tolerated and simple to take so that people can take the medications consistently without missing doses.
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Klinefelter Syndrome
Klinefelter syndrome, also referred to as XXY condition, is a genetic disease. Klinefelter syndrome affects mostly males. Symptoms include decreased testosterone levels, development of breasts, wider hips, and infertility. Some men with Klinefelter syndrome have no symptoms. Treatment includes educational, therapeutic, and medical therapy.
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Liver Disease
Liver disease can be cause by a variety of things including infection (hepatitis), diseases, for example, gallstones, high cholesterol or triglycerides, blood flow obstruction to the liver, and toxins (medications and chemicals). Symptoms of liver disease depends upon the cause and may include nausea, vomiting, upper right abdominal pain, and jaundice. Treatment depends upon the cause of the liver disease.
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Mumps
Mumps is an acute viral illness caused by the mumps virus. Symptoms and signs of mumps include fever, headache, muscle aches, tiredness, and loss of appetite, followed by swelling of the salivary glands.
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Obesity and Overweight
Get the facts on obesity and being overweight, including the health risks, causes, reviews of weight-loss diet plans, BMI chart, symptoms, causes, surgical and nonsurgical treatments, and medications.
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Sarcoidosis
Sarcoidosis, a disease resulting from chronic inflammation, causes small lumps (granulomas) to develop in a great range of body tissues and can appear in almost any body organ. However, sarcoidosis most often starts in the lungs or lymph nodes.
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Steroid Abuse
Anabolic steroids are synthetic substances that are related to testosterone and promote skeletal muscle growth and the development of male sexual characteristics in both men and women. In the 1930s, it was discovered that anabolic steroids could promote skeletal muscle growth in lab animals, which lead to anabolic steroid abuse by bodybuilders and weight lifters.
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Testicular Cancer
Testicular cancer symptoms include a painless lump or swelling in a testicle, testicle or scrotum pain, a dull ache in the abdomen, back, or groin, and a feeling of heaviness in the scrotum. Treatment for cancer of the testicles depends on the type of cancer (seminoma or nonseminoma), the stage of the cancer, and the patient's age and health.
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Tuberculosis (TB)
Mycobacterium tuberculosis is the bacterium that causes tuberculosis (TB). Symptoms and signs of TB include bloody sputum, fever, cough, weight loss, and chest pain. Treatment depends upon the type of TB infection.
Examples of Medications for Low Testosterone (Low T)
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Tartavoulle, Todd M., and Demetrius J. Porche. "Low Testosterone." Journal for Nurse Practitioners 8.10 (2012): 778-786. <https://www.medscape.com/viewarticle/775165>.