The loss of pain and/or temperature sensation can accompany any condition that damages the nerve pathways responsible for receiving, transmitting, or processing external stimuli. Therefore, problems with the peripheral nerves in the body as well as conditions affecting the brain or spinal cord may result in the loss of temperature sensation. A wide variety of conditions, ranging from tumors to chronic diseases to infections, can cause damage to the nerves that results in loss of sensation. When loss of sensation occurs in the setting of peripheral neuropathy (damage to the peripheral nerves in the body), antidepressant and antiseizure medications are sometimes used for relief.
Other causes of loss of temperature sensation
- Decompression Sickness
- Drugs/Toxins
- Friedrich's Ataxia
- Myelitis
- Myelopathy
- Paralysis
- Poisoning
- Radiation Therapy
- Radicular Neuropathy
- Spinal Cord Compression
- Spinal Cord Tumors
- Syringomyelia
- Trauma to Spinal Cord
- Vitamin B12 Deficiency
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Causes of Loss of Temperature Sensation
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Alcoholism and Alcohol Abuse
Alcoholism is a disease that includes alcohol craving and continued drinking despite repeated alcohol-related problems, such as losing a job or getting into trouble with the law. It can cause myriad health problems, including cirrhosis of the liver, birth defects, heart disease, stroke, psychological problems, and dementia. Counseling and a few medications can be effective for alcoholism treatment.
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Brain Tumors
A brain tumor can be either non-cancerous (benign) or cancerous (malignant), primary, or secondary. Common symptoms of a primary brain tumor are headaches, seizures, memory problems, personality changes, and nausea and vomiting. Causes and risk factors include age, gender, family history, and exposure to chemicals. Treatment is depends upon the tumor type, grade, and location.
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Burns (First Aid)
Burn types are based on their severity: first-degree burns, second-degree burns, and third-degree burns. First-degree burns are similar to a painful sunburn. The damage is more severe with second-degree burns, leading to blistering and more intense pain. The skin turns white and loses sensation with third-degree burns. Burn treatment depends upon the burn location, total burn area, and intensity of the burn.
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Cauda Equina Syndrome
Cauda equina syndrome is a medical emergency condition that is caused by the uncommon compression of the nerves at the end of the spinal cord. Symptoms of cauda equina syndrome include lower back pain, tingling and/or numbness in the buttocks and lower extremities, bowel or bladder incontinence, and weakness in the legs. Causes of cauda equina syndrome include herniated discs, hematomas, or infection. Treatment is generally prompt surgery.
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Drug Abuse and Addiction
Drug abuse and addiction is a chronic disease that causes drug-seeking behavior and drug use despite negative consequences to the user and those around him. Though the initial decision to use drugs is voluntary, changes in the brain caused by repeated drug abuse can affect a person's self-control and ability to make the right decisions and increase the urge to take drugs. Drug abuse and addiction are preventable.
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Fabry Disease
Fabry disease (Fabry's disease, alpha-galactosidase-A) is a genetic disorder with symptoms such as burning sensations in the hands, small-raised reddish-purplish blemishes on the skin, fever, decreases sweating, and gastrointestinal (GI) difficulties. Fabry disease patients are at increased risk of heart attack, heart disease, kidney failure, and stroke. Symptoms of Fabry disease can be treated with medication.
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Frostbite (Frostnip)
There are two categories of cold weather-related injuries. 1) no freezing of body tissue (trench foot and chilblains), and 2) freezing of body tissues (frostbite). Chilblains in general, will not need medical attention (unless there is infection). Trench foot and frostbite, however, require medical attention. Symptoms of frostbite include pain, burning, numbness, and eventually a complete loss of sensation in the affected body part. The young, elderly, and patients with certain medical conditions (diabetes, hypothyroidism, circulatory problems, and psychiatric illnesses), are more susceptible to cold weather-related injuries. People who abuse alcohol and illicit drug user are also at risk for cold weather-related injuries.
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Guillain-Barre Syndrome
Guillain-Barré syndrome is an autoimmune disease of the nervous system due to damage to the myelin sheath around nerves. It is the most acquired nerve disease (neuropathy) and usually follows a virus infection but can also be associated with immunizations, surgery, and childbirth. The cause is unknown but appears to be related to autoimmune reaction. Symptoms include weakness beginning in the legs and progressing upward, lost reflexes, and in severe cases, breathing can be affected. Patients can expect a slow but progressive recovery over several months maintaining vital functions and passively exercising the muscles. Plasmapheresis (removing toxic substances from the blood) has been shown to improve outcomes and shorten the disease as well as intravenous immunoglobulin.
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Herniated Disc
A herniated disc may be caused by injury or degeneration from age. Symptoms depend on the location of the herniation and whether nerve tissue is being irritated. An MRI or CT scan is performed to diagnose a herniated disc. Treatment may involve physical therapy, cortisone injection, pain medications, anti-inflammatory medications, muscle relaxants, and surgery.
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Kidney (Renal) Failure
Kidney failure can occur from an acute event or a chronic condition or disease. Prerenal kidney failure is caused by blood loss, dehydration, or medication. Some of the renal causes of kidney failure include sepsis, medications, rhabdomyolysis, multiple myeloma, and acute glomerulonephritis. Post renal causes of kidney failure include bladder obstruction, prostate problems, tumors, or kidney stones.Treatment options included diet, medications, or dialysis.
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Leprosy
Leprosy (Hansen's disease) is a disfiguring disease caused by infection with Mycobacterium leprae bacteria. The disease is spread from person to person through nasal secretions or droplets. Symptoms and signs of leprosy include numbness, loss of temperature sensation, painless ulcers, eye damage, loss of digits, and facial disfigurement. Leprosy is treated with antibiotics and the dosage and length of time of administration depends upon which form of leprosy the patient has.
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Lumbar Spinal Stenosis
Lumbar stenosis can be caused by degenerative arthritis (the most common cause), tumor, infection, or metabolic disorders (Paget's disease of the bone). Symptoms include low back pain, weakness, pain, numbness, and loss of sensation in the legs. Other conditions may cause similar symptoms of lumbar stenosis, including diabetic neuropathy, claudication, and peripheral vascular disease. Lumbar stenosis may be treated with medication or surgery.
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Lupus (Systemic Lupus Erythematosus or SLE)
Systemic lupus erythematosus is a condition characterized by chronic inflammation of body tissues caused by autoimmune disease. Lupus can cause disease of the skin, heart, lungs, kidneys, joints, and nervous system. When only the skin is involved, the condition is called discoid lupus. When internal organs are involved, the condition is called systemic lupus erythematosus (SLE).
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Multiple Sclerosis (MS)
Multiple sclerosis or MS is an autoimmune disorder in which brain and spinal cord nerve cells become demyelinated. This damage results in symptoms that may include numbness, weakness, vertigo, paralysis, and involuntary muscle contractions. Different forms of MS can follow variable courses from relatively benign to life-threatening. MS is treated with disease-modifying therapies. Some MS symptoms can be treated with medications.
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Polio
A polio infection causes symptoms and signs such as paralysis, limb deformities, and even death. There is no curative treatment for polio. Treatment focuses on pain control, bed rest, and physical therapy.
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Seizure (Epilepsy)
Epilepsy is a brain disorder in which the person has seizures. There are two kinds of seizures, focal and generalized. There are many causes of epilepsy. Treatment of epilepsy (seizures) depends upon the cause and type of seizures experienced.
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Sjogren's Syndrome
Sjögren's syndrome is an autoimmune disease involving the abnormal production of extra antibodies that attack the glands and connective tissue. It is also associated with a connective tissue disease, such as rheumatoid arthritis, systemic lupus erythematosus, or scleroderma, which is referred to as secondary Sjögren's syndrome. Though there is no cure for Sjögren's syndrome, the symptoms may be treated by using lubricating eye ointments, drinking plenty of water, humidifying the air, and using glycerin swabs. Medications are also available to treat dry eye and dry mouth.
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Stroke
A stroke is an interruption of the blood supply to part of the brain caused by either a blood clot (ischemic) or bleeding (hemorrhagic). Symptoms of a stroke may include weakness, numbness, double vision or vision loss, confusion, vertigo, difficulty speaking, or understanding speech. A physical exam, imaging tests, neurological exam, and blood tests may be used to diagnose a stroke. Treatment may include administration of clot-busting drugs, supportive care, and in some instances, neurosurgery. The risk of stroke can be reduced by controlling high blood pressure, high cholesterol, diabetes, and stopping smoking.
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Transient Ischemic Attack (TIA, Mini-Stroke)
When a portion of the brain loses blood supply, through a blood clot or embolus, a transient ischemic attack (TIA, mini-stroke) may occur. If the symptoms do not resolve, a stroke most likely has occurred. Learn the symptoms, risk factors, and treatment for a transient ischemic attack.
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What Is Diabetic Neuropathy?
Diabetic neuropathy a condition in which nerve damage has occurred as a complication of diabetes. The pain from the nerve damage can be severe with tingling or numbness in the part of the body affected. Diabetic neuropathy can occur anywhere in the body. Diabetic neuropathy can cause symptoms like intense pain, numbness, burning, or tingling in the part of the body affected by the condition. There are four types of neuropathy include peripheral, autonomic, proximal and focal. Natural therapies and medications may help relieve the pain and other symptoms of diabetic neuropathy.
Examples of Medications for Loss of Temperature Sensation
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