What is LEEP?
Loop electrosurgical excision procedure (LEEP), uses a low-voltage electrical current to remove abnormal tissues of the cervix. It has an advantage, therefore, over the destructive techniques (CO2 laser and cryocautery) in that an intact tissue sample for analysis can be obtained. LEEP also is popular because it is inexpensive, simple, and typically has few risks or side effects. LEEP is also known as large loop excision of the transformation zone (LLETZ).
This procedure is used most often for treating moderate dysplasia (abnormal changes of the cells lining the cervix or precancers) that have been identified by colposcopy and/or cervical biopsy. In certain situations, severe dysplasia and noninvasive cancer that are localized and can be removed may also be treated by LEEP.
How is a LEEP done?
The patient lies on an examining table with the feet elevated in stirrups (the position used to obtain a Pap smear). A speculum (as used for the Pap test) is inserted to open the vaginal walls. Sometimes a special solution, either vinegar (acetic acid) or iodine, is applied to the cervix prior to the procedure, which makes the abnormal areas of tissue more recognizable).
The area is numbed using a local anesthetic (cervical block). Oral or intravenous medications to control pain may also be given. A low-voltage electrical current is delivered via a thin wire that is passed through tissues to remove the abnormal areas of the cervix. A chemical is applied afterwards to prevent bleeding.
Mild pain and cramping that can be relieved by oral medications may occur for the first few hours following the procedure. Vaginal discharge and spotting commonly occur after this procedure for up to a few weeks. Sexual intercourse and tampons use should be avoided for several weeks to allow better healing. Douching should also be avoided.
How effective is LEEP?
LEEP has been shown to be comparable to cryotherapy, cold knife conization (surgical removal of the abnormal area), laser ablation (destruction of the abnormal tissue), and laser conization for the removal of abnormal or precancerous tissues of the cervix. Studies have shown that a majority of these methods result in a cure (removal of all the affected tissue).
Further treatment is not typically necessary if all of the abnormal area has been removed, although the precancerous changes may develop again (recur) at a later time. Regular follow-up Pap tests are required following LEEP to evaluate for possible recurrence of the cellular abnormalities.
What are complications of LEEP?
Complications occur in about a small percentage of women undergoing LEEP, including narrowing (stenosis) of the opening of the cervix, greater than expected amounts of bleeding, or infection of the cervix or uterus.
Wright, Jason D., M.D. "Patient information: Management of a cervical biopsy with precancerous cells (Beyond the Basics)." Uptodate.com. Updated Jan. 18, 2016.
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Cervical CancerCervical cancer is cancer of the entrance to the womb (uterus) caused by the human papillomavirus (HPV). Regular pelvic exams, Pap testing, and screening can detect precancerous changes in the cervix. Cervical cancer can be prevented by a vaccine. The most common signs and symptoms are an increase in vaginal discharge, painful sex, and postmenopausal bleeding. The prognosis and survival rate depend upon the stage at which the cancer was diagnosed.
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