Generic Name: L-methylfolate/pyridoxal 5-phosphate/methylcobalamin
Brand Name: Metanx
Drug Class: Food Supplements
What is L-methylfolate/pyridoxal 5-phosphate/methylcobalamin, and what is it used for?
L-methylfolate/pyridoxal 5-phosphate/methylcobalamin is a combination of three vitamins of the B group. L-methylfolate is the active form of vitamin B9, also known as folate, pyridoxal 5-phosphate is the active form of vitamin B6 and methylcobalamin is one of the two active forms of vitamin B12. The combination of B vitamins is a prescription medical food used under a physician’s supervision, to treat peripheral diabetic neuropathy.
Peripheral diabetic neuropathy is a kind of nerve damage caused by excessive sugar levels in patients with type 2 diabetes (diabetes mellitus). The combination of three water-soluble vitamins B9, B6 and B12 is specifically formulated to provide the nutritional supplements required to improve peripheral blood flow, and reduce nerve damage and neuropathy in patients with diabetes.
L-methylfolate is a coenzyme crucial for many cellular functions including metabolism of amino acids, DNA and RNA synthesis, and the synthesis and growth of all cells, particularly, red blood cells. Pyridoxal 5-phosphate is a coenzyme involved in protein synthesis, has multiple functions, and is essential for normal brain development and for keeping the nervous system and immune system healthy. Methylcobalamin is another micronutrient that is important for healthy functioning of the nervous system, formation of red blood cells and DNA synthesis.
The three B vitamins are naturally available in many foods, but diabetic patients with neuropathy often require supplemental amounts. Good dietary sources of folate include leafy green vegetables, legumes, eggs, beef liver, fruits and vegetables. Vitamin B6 rich foods include fish, beef liver and other organ meats, potatoes and other starchy vegetables, and fruit (other than citrus). Vitamin B12 sources include fish, meat, poultry, eggs, dairy and B12 fortified products such as breakfast cereals.
Warnings
- Do not take L-methylfolate/pyridoxal 5-phosphate/methylcobalamin if you are hypersensitive to any of its components
- L-methylfolate/pyridoxal 5-phosphate/methylcobalamin contains milk, soy and carmine; avoid or use with caution if you have intolerance or allergy to any of these products
- Doses of folic acid higher 0.1 mg/day may mask B12 deficiency pernicious anemia while irreversible nerve damage continues to progress; folic acid is the synthetic form of folate and L-methylfolate may be less likely than folic acid to mask vitamin B12 deficiency
What are the side effects of L-methylfolate/pyridoxal 5-phosphate/methylcobalamin?
Common side effects of L-methylfolate/pyridoxal 5-phosphate/methylcobalamin include:
L-methylfolate
- Allergic reactions
Pyridoxal 5-phosphate
- Nausea
- Vomiting
- Loss of appetite
- Abdominal pain
- Headaches
- Drowsiness (somnolence)
- Tingling or prickling sensations (paresthesia)
- Elevated liver function test results
- Allergic reactions
- Skin reactions
- Acne
- Light sensitivity (photosensitivity)
Methylcobalamin
- Temporary widespread skin rash (exanthema)
- Itching
- Swelling (edema)
- Excessive red blood cells (polycythemia vera)
This is not a complete list of all side effects or adverse reactions that may occur from the use of this drug.
Call your doctor for medical advice about serious side effects or adverse reactions. You may also report side effects or health problems to the FDA at 1-800-FDA-1088.

QUESTION
What is diabetic peripheral neuropathy? See AnswerWhat are the dosages of L-methylfolate/pyridoxal 5-phosphate/methylcobalamin?
Capsule
- 3mg/35mg/2mg
Adult:
Diabetic Peripheral Neuropathy
- A medical food for the clinical dietary management of endothelial dysfunction associated with diabetic peripheral neuropathy
- 1 capsule orally twice daily, or 2 capsules once daily
Pediatric:
- Safety and efficacy not established
Overdose
- In case of overdose of L-methylfolate/pyridoxal 5-phosphate/methylcobalamin or if you develop severe hypersensitivity symptoms, seek medical help immediately or contact Poison Control.
What drugs interact with L-methylfolate/pyridoxal 5-phosphate/methylcobalamin?
Inform your doctor of all medications you are currently taking, who can advise you on any possible drug interactions. Never begin taking, suddenly discontinue, or change the dosage of any medication without your doctor’s recommendation.
- L-methylfolate/pyridoxal 5-phosphate/methylcobalamin has no listed severe, serious, moderate or mild interactions with other drugs.
The drug interactions listed above are not all of the possible interactions or adverse effects. For more information on drug interactions, visit the RxList Drug Interaction Checker.
It is important to always tell your doctor, pharmacist, or health care provider of all prescription and over-the-counter medications you use, as well as the dosage for each, and keep a list of the information. Check with your doctor or health care provider if you have any questions about the medication.
Pregnancy and breastfeeding
- There are no well-controlled studies on use of L-methylfolate/pyridoxal 5-phosphate/methylcobalamin during pregnancy; use with caution if potential benefits outweigh potential fetal risks
- It is not known if L-methylfolate/pyridoxal 5-phosphate/methylcobalamin is excreted in breast milk; use with caution
What else should I know about L-methylfolate pyridoxal/5-phosphate/methylcobalamin?
- Take L-methylfolate/pyridoxal 5-phosphate/methylcobalamin exactly as prescribed
- Keep safely out of reach of children
- Seek medical help immediately if you develop severe allergic reactions
Health News
- Attachment Theory: What It Is, Stages & the Different Attachment Styles
- Gentle Parenting: What It Is, Techniques & Discipline
- U.S. Nursing Homes Fail to Report Many Serious Falls, Bedsores: Study
- The Younger You Get Diabetes, the Higher Your Risk for Dementia Later
- FDA Grants Full Approval to Paxlovid to Treat COVID-19
More Health News »
Summary
L-methylfolate/pyridoxal 5-phosphate/methylcobalamin is a combination of three vitamins of the B group, and is used to treat peripheral diabetic neuropathy. Common side effects include allergic reactions, nausea, vomiting, loss of appetite, abdominal pain, headaches, drowsiness (somnolence), temporary widespread skin rash (exanthema), itching, swelling(edema), and excessive red blood cells (polycythemia vera), and others. Use with caution if potential benefits outweigh potential fetal risks in pregnant women and women who are nursing infants.
Multimedia: Slideshows, Images & Quizzes
-
Type 2 Diabetes: Signs, Symptoms, Treatments
Learn about type 2 diabetes warning signs, symptoms, diagnosis, and treatment options. Find out why thirst, headaches, and...
-
Diabetes: What Raises and Lowers Your Blood Sugar Level?
Want to lower your blood sugar? Learn to better control your glucose levels by preventing blood sugar spikes and swings to avoid...
-
Diabetes Nerve Pain: Improving Diabetic Peripheral Neuropathy
Learn how to cope with the symptoms of diabetic peripheral neuropathy through pain management exercises. Find relief for diabetic...
-
Type 1 Diabetes (T1D): Symptoms, Causes, Treatments, Vs. Type 2
What is type 1 diabetes? There are new treatments for juvenile diabetes, and more people with diabetes can be treated than ever...
-
Diabetes: How Blood Sugar Levels Affect Your Body
High blood sugar can be a sign of diabetes or prediabetes. The drugs that treat it sometimes cause low blood sugar too. WebMD...
-
Foot Health: Reasons You Feel Burning in Your Feet
The feeling of burning in your feet isn't just an annoyance. It might also be a sign of a more serious condition. Find out more...
-
Diabetes Tips: Managing and Living With Diabetes
If you have either type 1 or type 2 diabetes, you need to approach life differently. Learn nutrition tips to control blood sugar,...
-
How Diabetes Can Affect Your Feet
Learn more about diabetes related foot problems. For people with diabetes, too much glucose in the blood can cause serious foot...
-
Prediabetes: You Can Turn It Around
Prediabetes can be a wake-up call. Click through to find out what you can do if you have it.
-
Picture of Necrobiosis Lipoidica Diabeticorum
Necrobiosis lipoidica diabeticorum. NLD is a skin rash that occurs on the shins, most commonly on women. It usually looks like a...
-
Diabetes: 12 Ways Too Much Sugar Harms Your Body
The bitter truth: How too much sugar can harm your physical and mental health.
-
Diabetes Diet: Healthy Meal Plans for Diabetes-Friendly Eating
Discover the best and worst meals for diabetes-savvy dining. See how to avoid carbs and control your blood sugar with healthier...
-
Diabetic Neuropathy Quiz: Test Your Medical IQ
Diabetic neuropathy is serious. Take this quiz to get the facts.
-
Diabetes: Best Foods for a Prediabetes Diet
Learn what to eat -- and possibly stop diabetes in in its tracks -- when you’ve been diagnosed with prediabetes.
-
Type 2 Diabetes: Test Your Medical IQ
What causes type 2 diabetes? Can it be prevented? Take this online quiz and challenge your knowledge of this common condition....
-
Type 1 Diabetes Quiz: Test Your Medical IQ
What are the causes of type 1 diabetes? Take this quiz and challenge your knowledge of causes, symptoms, diagnosis and treatments...
-
Diabetes Quiz: Test Your Medical IQ
Take the Diabetes Quiz and learn the causes, signs, symptoms, and types of this growing epidemic. What does diabetes have to do...
-
Picture of Diabetic Retinopathy
Diabetic retinopathy, a common complication of diabetes, affects the blood vessels in the retina (the thin light-sensitive...
-
Diabetes: Best Diets When You Have Diabetes
Which popular eating plans are safe and effective? The right diet will help you control your blood sugar, get a handle on your...
-
Diabetes Travel: Tips for Better Diabetes Control
Diabetes shouldn't stop you from traveling! Learn tips for packing diabetic supplies, controlling blood sugar while changing time...
-
Diabetes Diet: 11 Low-Sugar Drink Ideas
Searching for low-sugar drink ideas? This pictures slideshow has eleven beverages ideal for people with diabetes and those...
-
Diabetes: 15 Famous Celebrities With Diabetes
See pictures of celebrities that have been diagnosed with type 1 or type 2 diabetes including Mary Tyler Moore, Salma Hayek, and...
-
Slideshow: Diabetes Management in 10 Minutes
Learn 10 simple ways to better manage your diabetes. See tips for controlling blood sugar, diet and exercise and other helpful...
-
Diabetes: Guide to Diabetic Peripheral Neuropathy
Diabetes can damage the nerves that help you feel pain, heat, and cold, especially in your feet. Learn about the symptoms of...
-
Diabetes: Low-Carb Choices for Fast Food
Low carb and fast food don't often go together. Here's how to spot unhealthy carbs and make better choices from the menu.
-
10 Muscle-Building Exercises for Diabetes
Watch this slideshow on Diabetes and Exercise. If you have diabetes, see how strengthening your muscles with these 10 weight...
-
Diabetes: Diabetic Peripheral Neuropathy Treatment
This nerve damage is a common complication of both type 1 and type 2 diabetes. Find out how to prevent it, slow its progression,...
Related Disease Conditions
-
Normal Blood Sugar Levels In Adults with Diabetes
People with diabetes can manage and prevent low or high blood sugar levels (hyperglycemia or hypoglycemia) by keeping a log of your blood sugar levels when you are eating and fasting and eat foods that are high in carbohydrates and sugar, for example, buttered potatoes, candy, sugary desserts, and fatty foods. Blood tests, for example, the hemoglobin A1c test (A1c test) and urinalysis can diagnose the type of diabetes the person has. Diabetes during pregnancy, called gestational diabetes, should be managed by you and your OB/GYN or another healthcare professional. Extremely high levels of blood glucose in the blood can be dangerous and life threatening if you have type 1, type 2, or gestational diabetes. If you or someone that you are with has extremely high blood glucose levels, call 911 or go to your nearest Urgent Care or Emergency Department immediately. To prevent and manage high blood glucose levels in people with diabetes keep a log of your blood sugar levels, eat foods that are high in carbohydrates sugar, for example, buttered potatoes, candy, sugary deserts, and fatty foods that you can share with your doctor and other healthcare professionals.
-
Diabetes (Type 1 and Type 2)
Diabetes is a chronic condition characterized by high levels of sugar (glucose) in the blood. The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin dependent). Symptoms of diabetes include increased urine output, thirst, hunger, and fatigue. Treatment of diabetes depends on the type.
-
Type 2 Diabetes Diet Plan
A type 2 diabetes diet or a type 2 diabetic diet is important for blood sugar (glucose) control in people with diabetes to prevent complications of diabetes. There are a variety of type 2 diabetes diet eating plans such as the Mediterranean diet, Paleo diet, ADA Diabetes Diet, and vegetarian diets.Learn about low and high glycemic index foods, what foods to eat, and what foods to avoid if you have type 2 diabetes.
-
Pregnancy and Gestational Diabetes
Gestational diabetes is a form of diabetes that can occur during pregnancy. Pregnant women with gestational diabetes have not had the condition prior to becoming pregnant. Usually, gestational diabetes has no symptoms or signs and of gestational diabetes. Gestational diabetes can cause insulin resistance, hypoglycemia, hypoglycemia, and diabetic ketoacidosis. Treatment of gestational diabetes is managing the condition by checking your blood sugar as recommended, diet changes, getting enough exercise, and monitoring your baby's growth.
-
Diabetes-Related Dental Problems
Second Source WebMD Medical Reference
-
Type 2 Diabetes: Diagnosing Diabetes
Second Source WebMD Medical Reference
-
Controlling Diabetes
Second Source WebMD Medical Reference
-
Diabetes Symptoms in Women
Diabetes symptoms in women include vaginal itching, pain, or discharge, loss of interest or pain after having sex, polycystic ovarian syndrome (POS), and urinary tract infections or UTIs (which are more common in women. Symptoms of diabetes that are the same in women and men are excessive thirst and hunger, bad breath, and skin infections, darkening of skin in areas of body creases (acanthosis nigricans), breath odor that is fruity, sweet, or acetone, and tingling or numbness in the hands or feet, blurred vision, fatigue, tingling or numbness in the hands or feet, wounds that heal slowly, irritability, and weight loss or gain. Complications of type 1 and type 2 diabetes are the same, for example, skin, eye, and circulation problems, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), ketoacidosis, and amputation. If diabetes is not managed a person may not survive.
-
Type 2 Diabetes
Type 2 diabetes is a chronic condition that may be reversible with diet and lifestyle changes. Symptoms include excessive thirst, frequent urination, weight loss, fatigue, and an unusual odor to your urine. Most people don't know they have type 2 diabetes until they have a routine blood test. Treatment options include medications, a type 2 diabetes diet, and other lifestyle changes.
-
Diabetes Treatment: Medication, Diet, and Insulin
The major goal in treating diabetes is controlling elevated blood sugar without causing abnormally low levels of blood sugar. Type 1 diabetes is treated with: insulin, exercise, and a diabetic diet. Type 2 diabetes is first treated with: weight reduction, a diabetic diet, and exercise. When these measures fail to control the elevated blood sugar, oral medications are used. If oral medications are still insufficient, insulin medications are considered.
-
Diabetic Ketoacidosis
Diabetic ketoacidosis (DKA) is a complication of type 1 diabetes that is life threatening. If a person thinks they may have diabetic ketoacidosis they should seek medical care immediately. Diabetic ketoacidosis happens when a person's insulin levels in the blood become dangerously low. Symptoms of diabetic ketoacidosis include dehydration, abdominal pain, confusion, and nausea and vomiting. Diabetic ketoacidosis needs medical treatment. It cannot be treated at home.
-
Diabetes Symptoms in Men
Early symptoms of diabetes are different in men, such as low testosterone. In many cases, prediabetes that will progress to type 2 diabetes if it is not treated early.
-
Prediabetes
Prediabetes is a situation where a person's blood sugar levels are higher than they should be, but aren't high enough to be diagnosed with type 2 diabetes. There are no signs or symptoms of prediabetes. Some of the risk factors for prediabetes are high blood pressure, high cholesterol, heart disease, smoking, family history, poor diet, and lack of activity. Diet changes along with other healthy lifestyle changes are important in treating prediabetes.
-
Type 1 vs. Type 2 Diabetes: Differences
Diabetes mellitus is a metabolic condition in which a person's blood sugar (glucose) levels are too high. Over 29.1 million children and adults in the US have diabetes. Of that, 8.1 million people have diabetes and don't even know it. Type 1 diabetes (insulin-dependent, juvenile) is caused by a problem with insulin production by the pancreas. Type 2 diabetes (non-insulin dependent) is caused by: Eating a lot of foods and drinking beverages with simple carbohydrates (pizza, white breads, pastas, cereals, pastries, etc.) and simple sugars (donuts, candy, etc.) Consuming too many products with artificial sweeteners (We found out that they are bad for us!) Lack of activity Exercise Stress Genetics While the signs and symptoms of both types of diabetes are the same, which include: Increased urination Increased hunger Increased thirst Unexplained weight loss. However, the treatments are different. Type 1 diabetes is insulin dependent, which means a person with this type of diabetes requires treatment with insulin. People with type 2 diabetes require medication, lifestyle changes like eating a healthy diet, and getting regular exercise.
-
How Many Carbs Should a Diabetic Have in a Day?
Diabetes is a metabolic illness that affects blood sugar levels. With diabetes, you should try to get half of your daily calories from carbs. Foods that help lower blood sugar include whole grains, leafy green vegetables, fruit, low-fat dairy, lean protein, sugar substitutes, and olive, sunflower, or soybean oil.
-
Diabetes and Safe Medications for Colds & Flu
If you have diabetes and catch a cold or the flu, can be more difficult to recover from infections and their complications, for example, pneumonia. Home remedies and over-the-counter (OTC) drugs used for the treatment of the signs and symptoms of colds and the flu may affect blood sugar levels in people with diabetes.Some medications are OK to take if you have diabetes get a cold or the flu include nonsteroidal anti-inflammatory drugs or NSAIDs, like acetaminophen (Tylenol) and ibuprofen (Motrin) to control symptoms of fever and pain. Most cough syrups are safe to take; however, check with your pediatrician to see what medications are safe to give your child if he or she has type 1 or 2 diabetes. If you have diabetes and are sick with a cold or flu, you need to check your blood sugar levels more frequently. Continue taking your regular medications. Eat a diabetic low-glycemic index diet rich in antioxidants. To prevent colds and the flu drink at least eight 8 ounce glasses of water a day. To replenish fluids, drink sports drinks like Gatorade and Pedialyte to replenish electrolytes. Avoid people who are sick, sneezing, coughing, or have other symptoms of a cold or flu.
-
Diabetic Diet
A diabetic diet, or diabetes diet helps keep blood glucose levels in the target range for patients. Exercise and medication may also help stabilize blood glucose levels. Keeping track of when you take your diabetic medicine, keeping track of food choices, eating the proper amount of fruits, vegetables, carbohydrates, and fats will also help maintain proper blood glucose levels.
-
Which is Worse - Type 1 or Type 2 Diabetes?
Learn about the similarities and differences between Type 1 and Type 2 Diabetes.
-
What Baked Goods Can People With Diabetes Eat?
Although most baked items have a high carbohydrate content, which is undesirable for a person with diabetes, several baked meal options are diabetes-friendly.
-
Type 1 Diabetes (Symptoms, Causes, Diet, Treatment, Life Expectancy)
Type 1 diabetes mellitus (juvenile) is an auto-immune disease with no known cause at this time, although there are a few risk factors. Symptoms of type 1 diabetes include frequent urination, unintentional weight loss, dry and itchy skin, vision problems, wounds that heal slowly, and excessive thirst. Type 1 diabetes is diagnosed with blood tests. A healthy lifestyle and controlling blood glucose levels can improve life expectancy.
-
Gestational Diabetes (Diabetes during Pregnancy))
Learning how to avoid gestational diabetes is possible and maintaining a healthy weight and diet before and during pregnancy can help. Discover risk factors, tests and treatments for, and signs and symptoms of gestational diabetes.
-
What Is Diabetic Neuropathy?
Diabetic neuropathy a condition in which nerve damage has occurred as a complication of diabetes. The pain from the nerve damage can be severe with tingling or numbness in the part of the body affected. Diabetic neuropathy can occur anywhere in the body. Diabetic neuropathy can cause symptoms like intense pain, numbness, burning, or tingling in the part of the body affected by the condition. There are four types of neuropathy include peripheral, autonomic, proximal and focal. Natural therapies and medications may help relieve the pain and other symptoms of diabetic neuropathy.
-
Can Erectile Dysfunction Caused By Diabetes Be Reversed?
Erectile dysfunction is a frustrating condition where your penis cannot get or maintain an erection firm enough for sex. There is no specific treatment to reverse damage to blood vessels caused by diabetes, there are several options to help you have erections.
-
Can a Fit Person Get Diabetes?
No matter how thin or fit you are, you can still get diabetes. About 10%-15% of people with type II diabetes are at a healthy weight, a condition called lean diabetes.
-
Is Diabetes Inherited From Mother or Father?
Diabetes is a hereditary disease, which means that the child is at high risk of developing diabetes compared to the general population at the given age. Diabetes can be inherited from either mother or father.
-
Are Bananas Good for Diabetes?
Bananas are a type of fruit that is rich in fiber, carbohydrates, vitamin B6, phytonutrients, antioxidants and potassium. People who have diabetes can consume bananas in moderation, preferably if they are small, unripe and eaten along with protein and healthy fats.
-
Why Is Diabetes Increasing in the United States
As per the National Diabetes Statistics Report (2020), around 34.2 million people in the United States have diabetes.
-
How to Prevent Diabetes Naturally
Prediabetes is a condition in which a person has early symptoms of diabetes, but has not yet fully developed the condition. If prediabetes is not treated with lifestyle changes, the person could develop type 2 diabetes. Type 2 diabetes and prediabetes can be prevented with lifestyle changes, for example, eating a healthy diet, getting more exercise, reducing stress, quitting smoking, reducing or managing blood pressure and cholesterol, and managing any other health conditions or risk factors that you may have for developing type 2 diabetes.
-
Can Diabetes Make My Legs Hurt?
Yes, diabetes, particularly a poorly controlled diabetes where the blood sugars are high, is a major cause of pain and uncomfortable sensations in the leg. Diabetic leg pain may present as a dull ache in the soles, calves, and thighs or present with pins and needles like sensation in the lower limb.
-
What Are the Early Signs of Diabetes?
The early signs of diabetes depend on if one has type 1 or type 2 diabetes. Type 1 diabetes usually occurs in children, whereas type 2 diabetes is prevalent in adults.
-
What Is the New Technology for Diabetes?
Diabetes management has seen a significant transition in recent years as a result of technological advancements. Diabetes technology comes in various forms and has the potential to change the way you manage your condition in the future.
-
Diabetes Foot Problems
Diabetes related foot problems can affect your health with two problems: diabetic neuropathy, where diabetes affects the nerves, and peripheral vascular disease, where diabetes affects the flow of blood. Common foot problems for people with diabetes include athlete's foot, fungal infection of nails, calluses, corns, blisters, bunions, dry skin, foot ulcers, hammertoes, ingrown toenails, and plantar warts.
-
Eye Problems and Diabetes
Diabetes and eye problems are generally caused by high blood sugar levels over an extended period of time. Types of eye problems in a person with diabetes include glaucoma, cataracts, and retinopathy. Examples of symptoms include blurred vision, headaches, eye aches, pain, halos around lights, loss of vision, watering eyes. Treatment for eye problems in people with diabetes depend on the type of eye problem. Prevention of eye problems include reducing blood pressure, cholesterol levels, quitting smoking, and maintaining proper blood glucose levels.
-
Is Diabetes Insipidus Life-Threatening?
Diabetes insipidus (DI) is an uncommon disease that manifests as a frequent urge for urination and extreme thirst. It has nothing to do with blood sugar levels. Although in both diabetes mellitus and insipidus, patients experience a large volume of urine production, the cause is completely different.
-
Types of Diabetes Type 2 Medications
Type 2 diabetes oral medications are prescribed to treat type 2 diabetes in conjuction with lifestyle changes like diet and exercise. There are nine classes of drugs approved for the treatment of type 2 diabetes. Examples of type 2 oral diabetes medications include acarbose (Precose), chlorpropamide (Diabinese), glipizide (Glucotrol, Glucotrol XL), and metformin (Glucophage). Side effects, drug interactions, warnings and precautions, dosage, and breastfeeding and pregnancy safety information should be reviewed prior to taking any medication.
-
What Percentage of Japanese Have Diabetes?
The prevalence of diabetes has been on the rise in Japan in recent years. The increase can be ascribed to a sedentary lifestyle and increased fat consumption.
-
What Country Has the Most Type 1 Diabetics?
According to research, type 1 diabetes is most common among non-Hispanic Caucasians, followed by African Americans and Hispanic Americans. The highest incidence rates are found in Finland and Italy and the lowest rates are found in South American countries, such as Venezuela and Brazil and Asian countries, such as China or Thailand.
-
What Tools Are Used for Diabetes?
With improvements in medical science and technology, various methods have evolved to manage your blood sugar levels more effectively. Learn six devices that can be used to measure blood sugar levels and keep diabetes in check.
-
Is Diabetes A Lifestyle Choice
Diabetes mellitus or diabetes is a metabolic disease that is characterized by high levels of blood sugar (glucose).
-
Is Avocado Good for Diabetes Type I And Type II?
Avocados are great to include in a diabetes diet plan because they can help you manage your blood sugar levels and maintain overall health.
-
What Fruits Should Diabetics Avoid?
Managing diabetes successfully is about managing a combination of blood glucose levels. Diabetics do not have to avoid fruit, but they should adhere to sensible portion sizes and watch their overall carb intake.
-
What Population Is Most Affected by Diabetes?
Diabetes can affect anyone, but certain ethnic groups are more affected by it than others.
-
Hypoglycemia Without Diabetes: Causes and Diet
Hypoglycemia (low blood sugar level) is a condition most seen in patients with diabetes, who are on insulin or medications. Hypoglycemia is uncommon to happen in people without diabetes.
-
Which Country Has the Highest Diabetes Rate?
Diabetes mellitus (DM), or simply referred to as diabetes, is a condition that impairs the body's ability to use blood glucose, known as blood sugar, and other nutrients including fats and proteins. Insulin, a hormone produced by the pancreas, helps glucose from the food get into the cells to be used for the production of energy.
-
Are Spas Good for Diabetics?
Recent studies have reported that spas and hot tub therapy may help lower blood sugar levels and increase insulin absorption in patients with diabetes.
-
What Is the Difference Between Diabetes Insipidus and Diabetes Mellitus?
Diabetes affects the way your body turns food into energy. Diabetes insipidus causes thirst due to dehydration from constant urination while diabetes mellitus causes thirst due to high glucose levels in the blood.
-
What Are the 3 Most Common Symptoms of Undiagnosed Diabetes?
Diabetes mellitus has become a worldwide epidemic, thanks to changing lifestyles and increasing obesity. Type 2 diabetes affects approximately 13% of the population of the United States. Worldwide prevalence of diabetes is estimated to be around 463 million people. Type 2 diabetes accounts for over 90% of patients with diabetes.
-
How and Why Does Ethnicity Affect Diabetes?
Diabetes is a condition that causes elevated blood sugar levels. Acquired risk factors are associated with diabetes although ethnicity plays a role in increasing the incidence of the condition.
-
What Supplies Do You Need for Type 2 Diabetes?
Supplies like a blood sugar meter, insulin syringe, pen, or pump, and continuous glucose monitor can help you monitor and control your blood sugar levels and manage your Type 2 diabetes.
-
Can Type 2 Diabetes be Cured?
Type 2 diabetes is a long-term medical condition in which the body is not able to regulate blood sugar (glucose) level because of the inability of the body to properly use insulin. An individual can get type 2 diabetes because of a number of factors that reduce insulin action or quantity in the body. The goals of diabetes management are to eliminate symptoms and prevent the development of complications. Many drugs, both oral and injectable, are available for diabetes management.
-
Can Type 1 Diabetes be Cured?
Type 1 diabetes is a disorder of the pancreas. The organ doesn't make enough insulin. Learn what medical treatments can help ease your type 1 diabetes symptoms and speed up your recovery.
-
What Is Type 1 Diabetes and How Do You Get It?
What is type 1 diabetes? Learn the differences between type 1 and type 2 diabetes, as well as the symptoms and treatments for type 1 diabetes.
-
What Are the Four Types of Diabetic Neuropathy?
Diabetic neuropathy is a common complication of type 1 and type 2 diabetes. Diabetic neuropathy can be extremely painful. It can also lead to life-threatening health conditions like foot ulcers, amputations, heart attacks, digestion problems, and low blood sugar. Neuropathy mainly occurs due to high blood sugar for a prolonged period.
-
What Are the Warning Signs of Gestational Diabetes?
Gestational diabetes is diabetes that develops in a woman during pregnancy. Warning signs of gestational diabetes include increased thirst, tiredness, nausea and vomiting, and other signs.
-
What Tests Should Be Done for Diabetes?
Testing for diabetes is important because early detection and treatment can help maintain healthy blood glucose levels and lower the rate of premature death. Learn the ten best tests to diagnose diabetes here.
-
Tips for Managing Type 1 and 2 Diabetes at Home
Managing your diabetes is a full time commitment. The goal of diabetic therapy is to control blood glucose levels and prevent the complications of diabetes. Information about exercise, diet, and medication will help you manage your diabetes better. Blood glucose reagent strips, blood glucose meters, urine glucose tests, tests for urinary ketones, continuous glucose sensors, and Hemoglobin A1C testing information will enable you to mange your diabetes at home successfully.
-
Do Certain Ethnic Groups Have a Higher Risk of Diabetes?
One out of every 10 people in the United States has diabetes. Pacific Islanders, Alaskan natives and American Indians have the highest prevalence rates of diabetes among groups studied in the United States Census.
-
Is Quinoa Good for Diabetes?
Quinoa (pronounced as keen-wah) or Chenopodium quinoa is an annual herb of the goosefoot family. The herb is known for its edible starchy seeds. It is native to the Andean highlands and is popular over the world for its health benefits. Quinoa seeds may be used as cooked grains or grounded into flour.
-
How Do You Get Rid of Diabetic Sores?
If you have developed a diabetic sore or ulcer, your doctor may perform a procedure called debridement, which removes dead tissue from the wound to promote healing.
-
Can Diabetic Macular Edema Be Cured?
Diabetic macular edema (DME) is a condition that causes fluid accumulation in the macula. Diabetic macular edema can be cured by tackling the underlying medical cause and treating abnormal eye changes caused by the condition.
-
What Are the Four Stages of Diabetic Retinopathy?
Diabetic retinopathy is a condition that affects a person with diabetes. This happens when high blood sugar levels cause damage to blood vessels in the retina. In some, the blood vessels swell and leak or can obstruct the blood flow whereas, in some, there may be a growth of abnormal new vessels on the surface of the retina.
-
What Is A Good Daily Menu for a Diabetic?
If you live with diabetes, you are encouraged to follow the guidelines for a healthy diet. Eat a wide range of foods but limit sugar, high glycemic carbs, fats, and salt.
-
How Many Types of Diabetes Are There?
There are four major types of diabetes and there are many other types of diabetes due to genetic mutations, health conditions, and other factors.
-
Can Diabetes Cause Lack of Sleep?
Diabetes can cause lack of sleep and poor sleep quality. This is often due to fluctuating blood sugar levels, which can cause frequent nighttime urination.
-
What Things Should a Diabetic Check for Daily on Their Feet?
If you suffer from diabetes, look for the following signs on your feet. You should also get your feet evaluated once a year by a doctor.
-
Which Type of Diabetes Is Worse for COVID?
COVID-19, the disease caused by the SARS-CoV-2 virus, is a mild illness in most people. People with type 1 diabetes have 3.5 times the risk of dying compared to people without diabetes and people with type 2 diabetes have double the mortality risk with this viral infection.
-
What Is Diabetic Macular Edema (DME)?
Diabetic macular edema (DME) is an ocular complication of diabetes that develops over a period of time.
-
What Are the Early Signs of Type 2 Diabetes?
Type 2 Diabetes is a chronic disease characterized by increased blood sugar (glucose) level. Type 2 Diabetes is caused by either insufficient insulin secretion or resistance to that hormone’s action. Insulin is produced by the pancreas and helps process the glucose in the blood. Thus, with inadequate insulin, the bodies can’t burn all the blood sugar for energy in an efficient way. This means the glucose level in the blood rises, causing a variety of symptoms and when severe may even lead to death.
-
How Do You Prevent Diabetic Macular Edema?
Diabetic macular edema (DME) is an eye condition that affects people with diabetes, both type 1 and type 2 diabetes. Diabetic macular edema is a major contributor to several cases of blindness in the United States.
Treatment & Diagnosis
- Diabetes
- Diabetic Ketoacidosis (DKA)
- Prediabetes
- Diabetic Neuropathy
- Gestational Diabetes
- Diabetic Eye Disease
- Diabetes: Dealing with the Complications
- Diabetes: Monitoring Your Sugar Levels
- Diabetes: Meeting the Diabetes Challenge
- Diabetes Update -- Brunilda Nazario, MD
- Diabetes: Your Guide to Life With Diabetes
- Diabetes- Keeping Watch: Daily Diabetes Monitoring
- Diabetes: Maintaining Control
- Diabetes and Your Heart
- Diabetes and Diet: What Do I Eat?
- Diabetes: Maintaining Control with Nutrition
- Diabetes & Fitness: Get Moving!
- Diabetes Alert Day
- Diabetes: Scientific Research for Type I Diabetes
- Diabetes: Dealing with Your New Diagnosis
- Diabetes: Your Treatment Options
- Diabetes: Psychological Challenges
- Diabetes FAQs
- Diabetic Neuropathy FAQs
- Type 2 Diabetes FAQs
- Type 1 Diabetes FAQs
- What if I get COVID-19 with Diabetes?
- Diabetics: Is the New Inhaled Insulin Right for You?
- Rheumatoid Arthritis & Diabetes Gene (PTPN22)
- Diabetes Mellitus - The Work Pays Off
- Diabetes - Foot Care: A Walking Matter
- Gee - Whats in a Name
- Diabetes - An Aspirin A Day
- Diabetes and Eye Disease...See No Evil
- Diabetes - David Meets Goliath
- Insulin...Getting Better All the Time
- Exercise Therapy in Type 2 Diabetes - Part 1
- Exercise Therapy in Diabetes - Part 2
- Insulin Resistance - Keypoints
- Ramipril, Heart Disease, Stroke & Diabetes
- Diabetes Type I...Insulin Therapy
- Heart Disease Stroke and Diabetes
- Hypoglycemia (Low Blood Sugar) Symptoms and Diabetes
- What Foods to Eat to Reverse Diabetes
- How Bad Is Type 1 Diabetes?
- What Causes Type 1 Diabetes in Adults?
- Is Type 1 Diabetes Genetic?
- What Will Happen if Type 1 Diabetes Is Left Untreated?
- Can You Get Diabetes from Stress?
- How Do You Know if You Have Diabetes?
- Can oral diabetes medications cause impotence?
- Does Diabetes Cause Gum Disease?
- What Is the Treatment for Diabetes Eye Damage?
- Does Celiac Disease Cause Diabetes?
- Does Anti-Retroviral Therapy for HIV Cause Diabetes?
- What Are Risk Factors for Diabetic Kidney Disease?
- Can You Have Type 1 Diabetes Without Symptoms?
- What Are the Best Shoes for Diabetic Neuropathy in Feet?
- What Is the Treatment for Diabetic Neuropathy?
- Can Chemotherapy Cause Diabetic Neuropathy?
- 6 Frequently Asked Diabetes Question
- What Is a Safe Hemorrhoid Treatment for Diabetics?
- What Kind of Candy Can You Eat With Diabetes?
- Is Weight Loss Caused by Diabetes Dangerous?
- Can a Diabetic Get a Deep Tissue Massage?
- Can Diabetes Cause Muscle Pain?
- What Kind of Cold Medicine Can Diabetics Take?
- 11 Diabetes Diet Tips for the Holidays
- Diabetes Diet
- Top 10 Questions to Ask Your Doctor About Diabetes
- Diabetic Ketoacidosis Symptoms
- Prediabetes Symptoms and Diagnosis
- Chocolate Buying Guide: Dieters & Diabetics
- Diabetes: Eating Well with Type 2 Diabetes
- Diabetes: What Can I Eat?
- Diabetics & Fitness: Exercise Can Save Your Life
Health Solutions From Our Sponsors

Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
https://reference.medscape.com/drug/metanx-l-methylfolate-pyridoxal-5-phosphate-methylcobalamin-999834#0
https://www.metanx.com/pdf/METANXCapsulesPIStatement.pdf
https://ods.od.nih.gov/factsheets/Folate-HealthProfessional/
https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/
https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/