Liposarcoma: Symptoms & Signs

Medically Reviewed on 5/27/2021

Liposarcoma is a type of malignant tumor (cancer) that originates in fat cells in the deep soft tissues of the body.

Signs and symptoms of a liposarcoma depend on the size of the tumor and its location in the body. Depending on the exact location, the symptoms can be quite variable. Associated symptoms and signs may include a

  • new lump anywhere on your body,
  • an existing lump that grows persistently, or
  • painful swelling or numbness in the area around a lump.

Other signs and symptoms might include

Cause of liposarcoma

The exact cause of liposarcoma is not understood, but risk factors for developing this tumor include radiation exposure, exposure to certain chemicals, and having certain inherited cancer risk syndromes.

Other liposarcoma symptoms and signs


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Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.