Tradjenta (linagliptin)

• Tradjenta is combined with diet and exercise to improve blood glucose levels in patients with type 2 diabetes.
• It should not be used for treating type 1 diabetes or diabetic ketoacidosis because it would not be effective in these conditions.
• Tradjenta has not been studied in patients with a history of pancreatitis. It is unknown whether Tradjenta increases the risk for the development of pancreatitis in patients who have a history of pancreatitis.

What brand names are available for linagliptin?

Tradjenta

Is linagliptin available as a generic drug?

No

Do I need a prescription for linagliptin?

Yes

The most common side effects of Tradjenta are:

• Stuffy or runny nose
• Sore throat
• Allergic reactions
• Muscle pain
• Diarrhea
• Increased uric acid levels
• Cough

Hypoglycemia may occur when Tradjenta is combined with insulin or a sulfonylurea-type drug.

Possible serious side effects include:

• Pancreatitis
• Severe joint pain
• Severe allergic reactions (anaphalaxis)

Tradjenta may be taken with or without food. The recommended dose is 5 mg once daily.

• Rifampin decreases the blood concentration of Tradjenta by stimulating break down of Tradjenta by CYP3A4 liver enzymes. Other drugs that increase activity CYP3A4 may also reduce the blood concentration of Tradjenta.

• There are no adequate studies of Tradjenta in pregnant women.
• It is unknown whether Tradjenta is secreted in human breast milk.

What preparations of linagliptin are available?

Tablets: 5 mg

How should I keep linagliptin stored?

Tablets should be stored at room temperature, 15-30 C (59-86 F)