- Heartburn Slideshow: Foods to Eat, Foods to Avoid
- 10 Facts About the Amazing Brain
- Weight Gain Shockers Slideshow Pictures
- What is lidocaine w/prilocaine cream, and how does it work (mechanism of action)?
- What are the uses for lidocaine w/prilocaine cream?
- What are the side effects of lidocaine w/prilocaine cream?
- What is the dosage for lidocaine w/prilocaine cream?
- Which drugs or supplements interact with lidocaine w/prilocaine cream?
- Is lidocaine w/prilocaine cream safe to take if I'm pregnant or breastfeeding?
- What else should I know about lidocaine w/prilocaine cream?
What is lidocaine w/prilocaine cream, and how does it work (mechanism of action)?
Lidocaine and prilocaine is a topical anesthetic cream. Lidocaine and prilocaine enter through the skin and block pain receptors in nerve endings. Lidocaine and prilocaine reduce conduction of nerve impulses by interrupting the transfer of sodium ions across the membranes of nerve cells. This results in a local anesthetic action. The FDA approved lidocaine/prilocaine in December 1992.
What are the uses for lidocaine w/prilocaine cream?
Lidocaine and prilocaine cream is commonly used as a local anesthetic on normal intact skin and genital mucous areas, before minor procedures.
What brand names are available for lidocaine w/prilocaine cream?
DermacinRx, Prizopak, EMLA, Leva Set, Lidopril, Livixil Pak, LP Lite Pak, Oraqix, Relador Pak, Venipuncture CPI
Is lidocaine w/prilocaine cream available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for lidocaine w/prilocaine cream?
What are the side effects of lidocaine w/prilocaine cream?
Common side effects of lidocaine and prilocaine are:
Other rare side effects include:
- central nervous system depression,
- hypersensitivity reactions, and
- hypotension (low blood pressure).
What is the dosage for lidocaine w/prilocaine cream?
- Minor skin procedures: Apply 2.5 grams of cream over 20 to 25 cm2of skin surface for at least 1 hour.
- Major skin procedures: Apply 2 grams of cream per 10 cm2of skin and allow to remain in contact with the skin for at least 2 hours.
- Genital mucous membrane (female): Apply a thick layer (5 to 10 grams) of cream for 5 to 10 minutes.
- Male genital skin: Apply a thick layer of cream (1 g/10 cm2) to the skin surface for 15 minutes. Local anesthetic infiltration should be performed immediately after removal of cream.
- Birth to 3 month or weight less than 5 kg: Maximum of 1 gram of cream to be applied to the maximum area of 10 cm2 for the maximum application time of 1 hour.
- Three to 12 months or weight more than 5 kg: Maximum of 2 gram of cream to be applied to the maximum area of 20 cm2 for the maximum application time of 4 hour.
- One to 6 years or weight more than 10 kg: Maximum of 10 gram of cream to be applied to the maximum area of 100 cm2 for the maximum application time of 4 hour.
- Seven to 12 years or weight more than 20 kg: Maximum of 20 gram of cream to be applied to the maximum area of 200 cm2 for the maximum application time of 4 hour.
Lidocaine and prilocaine cream is not recommended in neonates with a gestational less than 37 weeks or infants younger than 12 months who are receiving treatment with methemoglobin-inducing agents.
Which drugs or supplements interact with lidocaine w/prilocaine cream?
Prilocaine may contribute to formation of methemoglobin in patients treated with other drugs known to cause methemoglobinemia.
Lidocaine and prilocaine should be used with caution with anti-arrhythmic drugs like amiodarone (Cordarone), sotalol (Betapace), bretylium, and dofetilide (Tikosyn) because of increased risk developing abnormal heart rate and rhythm.
Is lidocaine w/prilocaine cream safe to take if I'm pregnant or breastfeeding?
There are no adequate studies of lidocaine and prilocaine to determine safe and effective use in pregnant women.
Lidocaine and prilocaine may be excreted in breast milk; therefore, caution should be exercised before using them in nursing mothers.
What else should I know about lidocaine w/prilocaine cream?
What preparations of lidocaine w/prilocaine cream are available?
Lidocaine and prilocaine is a combination cream, containing 2.5% of each component. Lidocaine and prilocaine is available in 5 gram and 30 gram tubes.
How should I keep lidocaine w/prilocaine cream stored?
Cream should be stored at room temperature 20 C to 25 C (68 F to 77 F). The tube must be closed tightly at all times when not in use.
Latest Medications News
Daily Health News
Lidocaine and prilocaine (DermacinRx, Prizopak, EMLA, Leva Set, Lidopril, Livixil Pak, LP Lite Pak, Oraqix, Relador Pak, Venipuncture CPI) is a local topical anesthetic cream used on normal intact skin and genital mucous areas prior to minor medical procedures. Side effects, drug interactions, dosage, storage, and pregnancy safety should be reviewed prior to using this medication.
Multimedia: Slideshows, Images & Quizzes
Picture of Skin Tag
A small tag of skin that may have a stalk (a peduncle). See a picture of Skin Tag and learn more about the health topic.
Picture of Skin Tags
A small tag of skin that may have a stalk (a peduncle). See a picture of Skin Tags and learn more about the health topic.
Picture of Less Common Skin Cancers
Uncommon types of skin cancer include Kaposi's sarcoma; Merkel cell carcinoma; and sebaceous gland carcinoma. See a picture of...
Picture of Skin Cancer
Excessive exposure to sunlight is the main cause of skin cancer. See a picture of Skin Cancer and learn more about the health...
Related Disease Conditions
Skin cancers occur when skin cells undergo malignant transformations and grow into tumors. The most common types of skin cancer, basal cell carcinoma and squamous cell carcinoma, are highly curable when they are diagnosed and treated early. Sun exposure, tanning beds, depressed immune system, radiation exposure, and certain viral infections are risk factors for skin cancer. Skin cancers are treated with surgery or radiation. The prognosis of nonmelanoma skin cancers is generally very good.
Postherpetic neuralgia (PHN) is a painful complication of shingles. Symptoms include severe pain, itchy skin, and possible weakness or paralysis of the area. There is no treatment for postherapetic neuralgia that is effective for all patients.
Foreign Objects or Insects In the Ear
Objects or insects in the ear can be placed in the ear by patients themselves, or an insect crawling in the ear. Ear wax can also cause ear problems if Q-tips are overused to clean the ears. Symptoms of an object in the ear are inflammation and sensitivity, redness, or discharge of pus or blood. When to seek medical care for an object or insect in the ear is included in the article information.
Neuropathic pain is a chronic condition that leads to ongoing pain symptoms. Patients can be predisposed to developing neuropathic pain who have conditions such as: diabetes, cancer, stroke, HIV, vitamin deficiencies, shingles, and multiple sclerosis. Patient history and nerve testing are used to diagnose neuropathic pain. Antidepressants, antiseizure medications, and other types of medications are used to treat neuropathic pain. Many people with neuropathic pain are able to attain some level of relief.
Wrinkles, whether they be fine line or deep furrows, typically appear on areas of the body that receive a high amount of exposure to the sun. Smoking, light skin type, hairstyle, the way you dress, your occupational and recreational habits, and heredity are all factors that promote wrinkling. Medical treatments for wrinkles include antioxidants, moisturizers, alpha-hydroxy acids, and vitamin A acid. Cosmetic procedures that treat wrinkles include dermabrasion, microdermabrasion, glycolic acid peels, laser resurfacing, Botox, and fillers.
Pain Management: Neuropathic Pain
Neuropathic pain is chronic pain resulting from injury to the nervous system. The injury can be to the central nervous system (brain and spinal cord) or the peripheral nervous system (nerves outside the brain and spinal cord).
Treatment & Diagnosis
Medications & Supplements
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
FDA Prescribing Information.