lidocaine viscous

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

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What is lidocaine viscous, and how does it work (mechanism of action)?

Lidocaine viscous solution is a local anesthetic that is applied topically to treat painful mucous membranes or throat pain associated with oral diseases and for procedures involving the mouth or throat. Lidocaine provides pain relief by inhibiting the influx of sodium ions involved in the initiation and conduction of nerve impulses associated with the perception of pain. Lidocaine is a local amide anesthetic that is thought to reversibly block nerve conduction and thereby provide local pain relief.

What brand names are available for lidocaine viscous?

Xylocaine Viscous 2%

Is lidocaine viscous available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for lidocaine viscous?

Yes

What are the side effects of lidocaine viscous?

Common side effects are associated with the local application of lidocaine and may include stinging, burning, and mild nausea.

Serious adverse effects include:

Seizures, heart and lung failure, and death have occurred when children less than three were treated with lidocaine viscous solution.

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What is the dosage for lidocaine viscous?

Adults: 5-10 ml of lidocaine viscous is recommended for the treatment of painful mucous membranes of the mouth or throat. No more than 6 doses should be given in 24 hours and the maximum dose is 60 ml or 1200 mg lidocaine.

To provide anesthesia prior to insertion of medical instruments or catheters into the upper respiratory or digestive tracts, 10 to 15 ml (200 to 300 mg) is recommended not to exceed 400 mg/day.

To treat diseases of the upper gastrointestinal tract, 5 to15 ml of lidocaine is recommended not to exceed 60 ml or 1200 mg per day.

Children 2-12 years: Dosing is based on weight. Do not exceed 1 ml per 5 kg of child's weight per dose. Do not exceed 4 mg/kg or 4 doses in 24 hours.

Which drugs or supplements interact with lidocaine viscous?

Lidocaine topical administration results in low systematic or blood levels are therefore does not have any known clinically significant drug-drug interactions. The following drug interactions have been observed with intravenous lidocaine use.

Toxicity may result when lidocaine is used with other local anesthetics or drugs which are structurally related to amide-type local anesthetics. Antiarrhythmic drugs such as mexiletine and amiodarone may increase blood concentrations of lidocaine.

Lidocaine is mainly metabolized or broken down by liver enzymes. Strong inhibitors of these liver enzymes such as fluvoxamine, erythromycin, and itraconazole may decrease the breakdown of lidocaine and cause an increase in its blood concentrations.

Cimetadine and beta blockers such as propranolol may decrease blood levels of lidocaine by decreasing blood flow to the liver or by inhibiting liver enzymes that break down lidocaine.

Is lidocaine viscous safe to take if I'm pregnant or breastfeeding?

Lidocaine has not been adequately evaluated in pregnant women.

Lidocaine and its metabolites are secreted into breast milk. At therapeutic doses the secretions in the breast milk are small and generally do not harm the infant; patients should consult their doctors before taking this drug.

What else should I know about lidocaine viscous?

What preparations of lidocaine viscous are available?

Oromucosal solution: 2% (20 mg/mL)

How should I keep lidocaine viscous stored?

Lidocaine Viscous should be stored aft 15 C – 30 C (59 F – 86 –F).

REFERENCE: FDA Prescribing Information

Quick GuidePrescription Drug Abuse: Know The Warning Signs

Prescription Drug Abuse: Know The Warning Signs

Summary

lidocaine viscous solution (Xylocaine Viscous) is a drug used to treat inflammation of the mucous membranes of the mouth and throat. Side effects, drug interactions, dosage, storage, and pregnancy safety information should be reviewed prior to taking this medication.

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Reviewed on 9/18/2015
References
REFERENCE: FDA Prescribing Information

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