- Ketoconazole vs. Selenium Sulfide
- What are ketoconazole and selenium sulfide?
- What are the side effects of ketoconazole and selenium sulfide?
- What is the dosage of ketonazole vs. selenium sulfide?
- What drugs interact with ketonazole and selenium sulfide?
- Are ketoconazole and selenium sulfide safe to use while pregnant or breastfeeding?
Ketoconazole vs. Selenium Sulfide
- Ketoconazole and selenium sulfide are antifungal agents used to treat itching, flaking, scaling, and dry skin on the scalp due to dandruff. Ketoconazole and selenium sulfide are also used for treating seborrhea (a red, itchy rash) and tinea versicolor, a fungal infection of the skin.
- Brand names for ketoconazole include Nizoral, Nizoral A-D, Ketodan, Extina, Xolegel, and Kuric. Brand names for selenium sulfide include Head & Shoulders, Selsun Blue, SelRx, and Selsun Rx.
- Side effects of ketoconazole and selenium sulfide that are similar include hair loss (rare), and scalp tingling.
- Side effects of ketoconazole that are different from selenium sulfide include rash, itching, nausea, vomiting, abdominal pain, headache, dizziness, fatigue, impotence, blood count abnormalities, serious allergic reactions (anaphylaxis), and depression.
- Side effects of selenium sulfide that are different from ketoconazole include oily hair, dry hair, dry scalp, hair loss, hair discoloration, scalp irritation, skin irritation, sweating, burning sensation, garlic breath, or tremor.
What are ketoconazole and selenium sulfide?
Ketoconazole is an anti-fungal medication in the same family of drugs as fluconazole (Diflucan), itraconazole (Sporanox), and miconazole (Micatin, Monistat). It prevents growth of several types of fungi by preventing production of the membranes that surround fungal cells. It is an anti-fungal medication prescribed to treat fungal infections such as thrush, ringworm, jock itch, athlete's foot, dandruff, tinea versicolor, blastomycosis, histoplasmosis, and coccidiomycosis.
Selenium sulfide is a chemical agent commonly used for treating dandruff. It is an antifungal agent that also relieves itching, flaking, scaling, and dry skin on the scalp due to dandruff. Selenium sulfide is also used for treating seborrhea and tinea versicolor, a fungal infection of the skin.
What are the side effects of ketoconazole and selenium sulfide?
Ketoconazole generally is well tolerated. Commonly reported side effects of ketoconazole are:
- abdominal pain,
- impotence, and
- blood count abnormalities.
Other important side effects of ketoconazole are rare; they include:
Liver dysfunction also has been reported. Signs of liver problems include unusual fatigue, loss of appetite, nausea and vomiting, yellowing of the skin (jaundice), dark urine, and pale stools. Development of these symptoms while taking ketoconazole should be reported to a physician.
The common side effects of selenium sulfide are:
- Oily hair
- Dry hair
- Dry scalp
- Hair loss
- Hair discoloration
Other side effects of selenium sulfide include:
What is the dosage of ketonazole vs. selenium sulfide?
Ketoconazole may be taken with or without food. The oral dose range is 200-400 mg daily. Recurrent tinea versicolor is treated with 400 mg monthly. Topical formulations are administered to affected areas once or twice daily.
For treating dandruff, 5-10 mL of shampoo or lotion should be massaged into wet scalp 2 times per week for 2 weeks then once every 1-2 weeks to control dandruff. The shampoo or lotion should be left on the scalp for 2 to 3 minutes, then rinsed off3 or 4 times with water. The application should be repeated.
Tinea versicolor should be treated by applying lotion or shampoo to the affected area, leaving it on the skin for 10 minutes and then washing it off with water. It should be applied every day for 7 days. The foam should be rubbed into the affected skin every 12 hours.
What drugs interact with ketonazole and selenium sulfide?
There are no drug interactions listed for topical ketonazole.
There are no drug interactions listed for topical selenium sulfide.
Are ketoconazole and selenium sulfide safe to use while pregnant or breastfeeding?
Use of selenium sulfide during pregnancy has not been adequately evaluated. It is not known whether selenium sulfide is excreted in breast milk.
Ketoconazole and selenium sulfide are antifungal agents used to treat itching, flaking, scaling, and dry skin on the scalp due to dandruff. Ketoconazole and selenium sulfide are also used for treating seborrhea (a red, itchy rash) and tinea versicolor, a fungal infection of the skin. Rash, itching, nausea, and vomiting are side effects of these two topical agents.
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Related Disease Conditions
Dandruff (seborrhea) is a skin disorder that results from neither too much moisture nor too much oil. Dandruff can be treated with shampoos that contain tar, salicylic acid, zinc, selenium sulfide, or ketoconazole.
Is Dandruff (Seborrhea) Contagious?
Seborrheic dermatitis (dandruff) is a chronic condition in which skin on the scalp flakes and sheds. Dandruff is not contagious. Sunlight exposure and stress reduction can improve the symptoms and signs of dandruff.
Dandruff vs. Dry Scalp
Dandruff is a condition characterized by small white flakes that shed from the scalp. Dry scalp is simply dry skin on one's head. Dry scalp is uncommon, and dandruff is very common. Dandruff treatment and prevention incorporates the regular use of an anti-dandruff shampoo.
Head Lice vs. Dandruff
Dandruff is a condition that causes dry flakes on the scalp. Lice are parasites. Head lice infestations are very contagious. Both head lice and dandruff have similar signs and symptoms: scalp itching and tiny white material on the hair shafts. Lice treatment involves the application of over-the-counter shampoos that contain permethrin or pyrethrin followed by nit and louse removal with a fine-toothed comb. Dandruff treatment incorporates the use of anti-dandruff shampoo.
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