- Ketoconazole cream vs. clotrimazole cream: What's the difference?
- What are ketoconazole cream and clotrimazole cream?
- What are the side effects of ketoconazole cream and clotrimazole cream?
- What is the dosage of ketoconazole cream vs. clotrimazole cream?
- Are ketoconazole cream and clotrimazole cream safe to use while pregnant or breastfeeding?
Ketoconazole cream vs. clotrimazole cream: What's the difference?
- Ketoconazole cream and clotrimazole antifungal medications are prescribed to treat fungal infections such as jock itch, athlete's foot, ringworm, and tinea versicolor.
- Brand names for ketoconazole include Nizoral, Nizoral A-D, Ketodan, Extina, Xolegel, and Kuric.
- Brand names for clotrimazole include Lotrimin AF, Gyne-Lotrimin, Alevazol, and Desenex.
- Side effects of ketoconazole and clotrimazole that are similar include nausea, vomiting, and itching.
- Side effects of ketoconazole that are different from clotrimazole include rash, abdominal pain, headache, dizziness, fatigue, impotence, and blood count abnormalities.
- Side effects of clotrimazole that are different from ketoconazole include local redness, stinging, blistering, peeling, swelling, hives, or burning at the area of application.
What are ketoconazole cream and clotrimazole cream?
Ketoconazole cream is an azole antifungal drug. It belongs to the same family of drugs as fluconazole (Diflucan), miconazole (Micatin, Monistat), and itraconazole (Sporanox). Ketoconazole prevents growth of several types of fungi by preventing production of the membranes that surround fungal cells. Ketoconazole cream is prescribed to treat fungal infections such as ringworm, jock itch, athlete's foot, dandruff, and tinea versicolor.
Clotrimazole cream is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and miconazole (Micatin, Monistat). It prevents growth of several types of fungi by interfering with the production of the membrane that surrounds fungal cells. It is used topically on the skin or inserted vaginally to treat local fungal infections due to Candida albicans, including vaginal yeast infections, tinea versicolor, tinea pedis ("athlete's foot"), tinea cruris ("jock itch"), or tinea corporis (ringworm).
What are the side effects of ketoconazole cream and clotrimazole cream?
Stinging, swelling, irritation, or redness of the treated skin may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur:
- Open sores
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include:
- Itching or swelling (especially of the face, tongue, and throat)
- Severe dizziness
- Trouble breathing
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
The most commonly noted side effects associated with clotrimazole include:
- local redness,
- hives, or
- burning at the area of application.
Other side effects include nausea and vomiting, which may be caused by the oral forms.
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What is the dosage of ketoconazole cream vs. clotrimazole cream?
- Apply ketoconazole cream 2% once daily to cover the affected and immediate surrounding area. You may see clinical improvement fairly soon after treatment; however, candidal infections and tinea cruris and corporis should be treated for two weeks in order to reduce the possibility of recurrence.
- Patients with tinea versicolor usually require two weeks of treatment.
- Patients with tinea pedis require six weeks of treatment.
- Seborrheic dermatitis: Apply ketoconazole cream 2% to the affected area twice daily for four weeks or until clinical clearing.
- Clotrimazole cream, lotion, or solution is applied to the affected and surrounding skin areas, generally twice daily in the morning and evening.
- The vaginal cream is inserted via applicator once daily, preferably at night, for 7 consecutive days.
- The 100 mg vaginal suppository is inserted once daily, preferably at bedtime, for 7 consecutive days.
- The 200 mg vaginal suppository is inserted once daily for 3 days, preferably at bedtime.
Are ketoconazole cream and clotrimazole cream safe to use while pregnant or breastfeeding?
- This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
- It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
- Clotrimazole cream is very poorly absorbed into the blood and the body after application to the skin or the vagina. Studies in women in their second or third trimesters of pregnancy have demonstrated no ill effects. No data is available in pregnant women during their first trimester. Rats given large amounts of clotrimazole via the vagina have demonstrated no ill effects.
- It is not known if clotrimazole is secreted in breast milk.
Ketoconazole cream and clotrimazole are antifungal medications prescribed to treat fungal infections such as jock itch, athlete's foot, ringworm, and tinea versicolor. These medications prevent growth of several types of fungi by preventing production of the membranes that surround fungal cells. Clotrimazole is used topically on the skin or inserted vaginally to treat local fungal infections due to Candida albicans, including vaginal yeast infections.
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Related Disease Conditions
Jock itch is an itchy red rash that appears in the groin area. The rash may be caused by a bacterial or fungal infection. People with diabetes and those who are obese are more susceptible to developing jock itch. Antifungal shampoos, creams, and pills may be needed to treat fungal jock itch. Bacterial jock itch may be treated with antibacterial soaps and topical and oral antibiotics.
The term "ringworm" or "ringworms" refers to fungal infections that are on the surface of the skin. A physical examination of the affected skin, evaluation of skin scrapings under the microscope, and culture tests can help doctors make the appropriate distinctions. A proper diagnosis is essential to successful treatment. Among the different types of ringworm are the following: tinea barbae, tinea capitis, tinea corporis, tinea cruris, tinea faciei, tinea manus, tinea pedis, and tinea unguium.
Vaginal Yeast Infection (in Women and Men)
Vaginal yeast infections in women are caused by an organism called Candida albicans. Symptoms of a vaginal yeast infection include vaginal pain with urination, vaginal discharge, odor, and itching. Treatment is generally OTC medications. A man can contract a yeast infection from his female sexual partner. Symptoms of a yeast infection in men include penile itching. Treatment is with oral or topical medication.
Athlete's foot (tinea pedis) is a skin infection caused by the ringworm fungus. Symptoms include itching, burning, cracking, peeling, and bleeding feet. Treatment involves keeping the feet dry and clean, wearing shoes that can breathe, and using medicated powders to keep your feet dry.
Is Ringworm Contagious?
A fungus causes ringworm. Ringworm can be transmitted from person to person. Animals may also spread ringworm. Ringworm causes an itchy, ring-shaped red rash with hair loss. Treatment incorporates the use of topical medication.
Is a Yeast Infection Contagious?
Yeast are a fungi that has many types. A type of yeast that can cause infection in humans is called Candida. Candida can infect the mouth, vagina, penis, or other areas of the body. Symptoms of yeast infections depend on the area infected, however, may include itching, bumps on the skin, a reddish rash, or patches of skin that ooze a clear or yellow liquid. Most yeast infections are not contagious even though they are caused by a fungus.
Thrush and Other Yeast Infections in Children
Yeast infections are caused by an overgrowth of a type of fungus called Candida. Oral thrush is a yeast infection of the mouth and throat. Oral thrush and yeast infections are treated orally or topically with an antifungal antibiotic called nystatin.
Is Jock Itch (Tinea Cruris) Contagious?
Jock itch is a fungal infection in the groin area that causes a raised, itchy, red rash. Jock itch can typically be treated with antifungal medications. People may need to seek medical care for jock itch if the groin area becomes swollen, tender, if red streaks appear, or if the lymph nodes become swollen.
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