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- What is ketoconazole, and how does it work (mechanism of action)?
- What brand names are available for ketoconazole?
- Is ketoconazole available as a generic drug?
- Do I need a prescription for ketoconazole?
- What are the side effects of ketoconazole?
- What is the dosage for ketoconazole?
- Is ketoconazole safe to take if I'm pregnant or breastfeeding?
- What else should I know about ketoconazole?
What is ketoconazole, and how does it work (mechanism of action)?
Ketoconazole is an anti-fungal medication in the same family of drugs as fluconazole (Diflucan), itraconazole (Sporanox), and miconazole (Micatin, Monistat). It prevents growth of several types of fungi by preventing production of the membranes that surround fungal cells. The FDA approved ketoconazole in June 1981.
What brand names are available for ketoconazole?
Nizoral, Nizoral A-D, Ketodan, Extina, Xolegel, Kuric
What are the side effects of ketoconazole?
Ketoconazole generally is well tolerated. Commonly reported side effects of ketoconazole are:
- abdominal pain,
- impotence, and
- blood count abnormalities.
Other important side effects of ketoconazole are rare; they include:
Liver dysfunction also has been reported. Signs of liver problems include unusual fatigue, loss of appetite, nausea and vomiting, yellowing of the skin (jaundice), dark urine, and pale stools. Development of these symptoms while taking ketoconazole should be reported to a physician.
What is the dosage for ketoconazole?
Ketoconazole may be taken with or without food. The oral dose range is 200-400 mg daily. Recurrent tinea versicolor is treated with 400 mg monthly. Topical formulations are administered to affected areas once or twice daily.
Is ketoconazole safe to take if I'm pregnant or breastfeeding?
What else should I know about ketoconazole?
What preparations of ketoconazole are available?
Tablets: 200 mg; Shampoo: 1% and 2%; Cream: 2%, Gel: 2%, Foam: 2%
How should I keep ketoconazole stored?
- Store tablets at room temperature, 15 C to 25 C (59 F to 77 F) and protected from moisture.
- Store shampoo 1% between 2 C to 30 C (35 F to 86 F) and protected from light and freezing.
- Store shampoo 2% at or below 25 C (77 F) and protected from light.
- Store cream and foam at room temperature, 20 C to 25 C (68 F to 77 F).
- Store gel between 15C to 30 C (59 F to 86 F).
Ketoconazole (Nizoral, Extina, Xolegel, Kuric) is an anti-fungal medication prescribed to treat fungal infections such as thrush, ringworm, jock itch, athlete's foot, dandruff, tinea versicolor, blastomycosis, histoplasmosis, and coccidiomycosis. Side effects and drug interactions should be reviewed prior to taking this medication.
Multimedia: Slideshows, Images & Quizzes
Picture of Dandruff
A mild skin condition that produces white flakes that may be shed and fall from the hair. See a picture of Dandruff and learn...
Picture of Ringworm Tinea Pedis
Superficial fungal infection of the feet is somewhat unique because of the location. See a picture of Ringworm Tinea Pedis and...
Picture of Ringworm of the Hand
Ringworm may involve the hands, particularly the palms and the spaces between the fingers. See a picture of Ringworm of the Hand...
Picture of Athlete's Foot 2
Athlete's foot is a fungus that causes itching, redness, and cracking. See a picture of Athlete's Foot and learn more about the...
Picture of Types of Ringworm
Ringworm is a common skin disorder otherwise known as tinea. See a picture of Types of Ringworm and learn more about the health...
Picture of Ringworm Illustration
Ringworm is a fungal infection of the skin previously thought to be due to a parasite (worm). See a picture of Ringworm and learn...
Picture of Fixed Drug Eruption
A large red-violet plaque on the arm of a child. See a picture of Fixed Drug Eruption and learn more about the health topic....
Picture of Ringworm
This superficial skin infection, also known as tinea, is caused by fungi called dermatophytes. See a picture of Ringworm and...
Picture of Athlete's Foot 1
Athlete's foot is caused by a fungus that grows on or in the top layer of skin. See a picture of Athlete's Foot and learn more...
Related Disease Conditions
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Athlete's foot (tinea pedis) is a skin infection caused by the ringworm fungus. Symptoms include itching, burning, cracking,...
Thrush and Other Yeast Infections in Children
Yeast infections are caused by an overgrowth of a type of fungus called Candida. Oral thrush is a yeast infection of the mouth...
Dandruff (seborrhea) is a skin disorder that results from neither too much moisture nor too much oil. Dandruff can be treated...
Tinea versicolor is a fungus infection that mainly affects the skin of young people. Recognized by light or reddish brown spots,...
The term "ringworm" or "ringworms" refers to fungal infections that are on the surface of the skin. A physical examination of...
Thrush (Oral Candidiasis)
Thrush is an infection of the mouth caused by the Candida fungus. Symptoms of Thrush include pain or difficulty swallowing, a...
Leishmaniasis is a disease caused by the bite of an infected sand fly. The most common types of leishmania infection are...
Folliculitis is a skin condition that causes small red bumps to form around the hair follicles. Skin bacteria such as...
Jock itch is an itchy red rash that appears in the groin area. The rash may be caused by a bacterial or fungal infection. People...
Histoplasmosis (Cave Disease)
Histoplasmosis (cave disease) is a disease caused by a fungus called Histoplasma capsulatum. The symptoms are similar to those of...
Valley fever (coccidioidomycosis) is a disease caused by the inhalation of the Coccidioides immitis or C. posadasii fungus....
Is Dandruff (Seborrhea) Contagious?
Seborrheic dermatitis (dandruff) is a chronic condition in which skin on the scalp flakes and sheds. Dandruff is not contagious....
Dandruff vs. Dry Scalp
Dandruff is a condition characterized by small white flakes that shed from the scalp. Dry scalp is simply dry skin on one's head....
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.