What is sepsis?
- Sepsis is an illness that affects all parts of the body; it occurs in response to an infection and can become life-threatening.
- If not treated quickly, organ failure can occur, leading to septic shock, low blood pressure, and eventually, death. Sepsis is a general term that covers all types of infectious processes that can lead to the above symptoms.
- Many types of bacteria, viruses, and occasionally, fungi and parasites may cause sepsis; for the purpose of this article, the term pathogens will be used to include all of the above-mentioned organisms.
- Pathogens that cause sepsis usually first cause localized infections such as pneumonia, kidney infections, abdominal infections, sexually transmitted diseases, or septicemia (blood stream infections) that eventually may result in sepsis.
- The term sepsis is frequently preceded by other terms (for example, MRSA, neonatal, meningococcal, or neutropenic, for example); these terms usually indicate a sepsis subtype that may describe the infecting organism, like "MRSA sepsis" or a condition found in a subtype, like "neutropenic sepsis."
Is sepsis contagious?
Sepsis itself is not contagious, but the pathogens that cause sepsis are usually contagious. What this means is that the pathogens that may cause sepsis can be transferred, usually from person to person, directly or indirectly (by contaminated items like utensils or clothing). If the pathogens are transferred, the person may or may not develop sepsis; consequently, most septic individuals, while capable of transferring pathogens the cause infection, will not necessarily transfer the condition of sepsis. The pathogens that cause sepsis may remain viable for a while after the death of a person; these pathogens are contagious although sepsis is not.
How will I know if someone has sepsis?
Sepsis is sometimes difficult to diagnose because it shares symptoms from other conditions. However, if a person has any of the following symptoms that are common to individuals with sepsis, he/she or his/her guardians need to contact a physician urgently. If the symptoms are more severe, he or she should go to an emergency department:
- Fever and chills
- Rapid heart rate
- Rapid breathing
- Low blood pressure
- Rash
- Confusion and/or disorientation
There are new definitions of sepsis. A person who meets at least two of the following criteria, plus has confirmed or suspected infection according to the systemic inflammatory response syndrome (SIRS) meets the definition for sepsis:
- Elevated heart rate greater than 90
- Body temperature either high (greater than 100.4 F) or low (less than 98.6 F)
- Respiratory rate of greater than 20 breaths per minute or a reduced partial pressure of carbon dioxide (PaCO2) in arterial blood
- Abnormal white blood cell count (WBC) greater than 12,000 or less than 4,000 cells/ul or 10% bands (immature white blood cells)
Consequently, a physician usually determines if a person is septic by physical exam and blood tests; people who are septic require hospitalization and immediate treatment.
How does sepsis spread?
As stated previously, sepsis is not spread from person to person, although the pathogens that can cause sepsis may be spread among people, both directly and indirectly. However, sepsis spreads within a person's body, usually from a site of infection that is somewhat localized to one organ (for example, pneumonia in the lungs or a wound infection in the leg). When the localized infection is severe, the pathogen may reach the bloodstream, and when this happens, the pathogen spreads to other organs; in addition, some of the pathogens may quickly multiply in the blood. When these situations arise, the person's infection has spread internally, and the person is considered to be septic.
When will I know I am cured of sepsis?
Individuals can be cured of sepsis usually by being hospitalized and treated with IV antimicrobial medications that are effective against the organisms causing the infection. Surgical drainage or removal of the source may also be needed. Depending upon the exact cause of the infection, the duration that the person has been septic, and the severity of involvement of organs, recovery can be relatively quick, lengthy, or if treatment begins late in the septic process, organ damage and/or death may occur.
Sepsis is a serious condition; even patients with no signs of organ failure with a timely diagnosis have a 15%-30% chance of death; those patients with severe sepsis and shock have a death rate of about 40%-60%.
When should I contact a health care provider about sepsis?
The best time to contact a health care provider about sepsis is before it occurs. This may sound impossible, but in reality, it is easy to do. If a person has any signs of increasing difficulties or severe symptoms of any infectious disease (for example, pneumonia, meningitis, wound infections, or organ infections, such as kidney infections), he or she should contact a physician or go to an emergency department quickly. Appropriate treatment of infections can reduce the chance of developing sepsis. Alternatively, if a person develops signs and symptoms of SIRS listed above, they should immediately go to an emergency department.
The key to preventing poor outcomes (organ damage, death) of sepsis is early and appropriate diagnosis and treatment of the infecting pathogen.

SLIDESHOW
Bacterial Infections 101: Types, Symptoms, and Treatments See SlideshowTop Is Sepsis Contagious Related Articles
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Low blood pressure, also referred to as hypotension, is blood pressure that is so low that it causes symptoms or signs due to the low flow of blood through the arteries and veins. Some of the symptoms of low blood pressure include light-headedness, dizziness, and fainting if not enough blood is getting to the brain. Diseases and medications can also cause low blood pressure. When the flow of blood is too low to deliver enough oxygen and nutrients to vital organs such as the brain, heart, and kidneys; the organs do not function normally and may be permanently damaged.MRSA Infection
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Pneumonia
Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.Skin Rash
The word "rash" means an outbreak of red bumps on the body. The way people use this term, "a rash" can refer to many different skin conditions. The most common of these are scaly patches of skin and red, itchy bumps or patches all over the place.Sepsis (Blood Poisoning)
Sepsis (blood poisoning) is a potentially deadly infection with signs and symptoms that include elevated heart rate, low or high temperature, rapid breathing and/or a white blood cell count that is too high or too low and has more than 10% band cells. Most cases of sepsis are caused by bacterial infections, and some cases are caused by fungal infections. Treatment requires hospitalization, IV antibiotics, and therapy to treat any organ dysfunction.Sexually Transmitted Diseases (STDs)
Common sexually transmitted diseases (STDs) in women include gonorrhea, chlamydia, genital herpes, and HPV infection (genital warts). Learn about types, symptoms, and treatment.STDs in Men
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