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- What is ipratropium bromide inhaler, and how does it work (mechanism of action)?
- What brand names are available for ipratropium bromide inhaler?
- Is ipratropium bromide inhaler available as a generic drug?
- Do I need a prescription for ipratropium bromide inhaler?
- What are the side effects of ipratropium bromide inhaler?
- What is the dosage for ipratropium bromide inhaler?
- Which drugs or supplements interact with ipratropium bromide inhaler?
- Is ipratropium bromide inhaler safe to take if I'm pregnant or breastfeeding?
- What else should I know about ipratropium bromide inhaler?
What is ipratropium bromide inhaler, and how does it work (mechanism of action)?
Ipratropium bromide is a bronchodilator that dilates (enlarges) airways (bronchi) in the lungs. It is used in treating, symptoms of asthma, colds, allergies, and chronic obstructive pulmonary disease (COPD) due to emphysema or chronic bronchitis. Ipratropium blocks the effect of acetylcholine on airways (bronchi) and nasal passages. Acetylcholine is a chemical that nerves use to communicate with muscle cells. In asthma and chronic obstructive pulmonary disease, cholinergic nerves going to the lungs cause narrowing of the airways by stimulating muscles surrounding the airways to contract. The "anti-cholinergic" effect of ipratropium blocks the effect of cholinergic nerves, causing the muscles to relax and airways to dilate. Mucus glands in the nose also are controlled by nerves that use acetylcholine to communicate. By blocking acetylcholine, ipratropium helps relieve symptoms of allergies and the common cold by preventing secretion of mucus by mucus glands in the nose. When inhaled, ipratropium travels directly to airways, and very little is absorbed into the body. The FDA approved ipratropium in October 1995.
What are the side effects of ipratropium bromide inhaler?
The most common side effects associated with ipratropium are:
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What is the dosage for ipratropium bromide inhaler?
- The recommended dose for allergies is 2 sprays (0.03%) in each nostril 2 or 3 times daily.
- The dose for treating symptoms of the common cold is 2 sprays (0.06%) in each nostril 3 to 4 times daily.
- The dose for treating asthma is 8 inhalations every 20 minutes as needed for up to 3 hours.
- The dose for treating bronchospasms associated with COPD is 2 puffs 4 times daily and additional puffs if needed but not to exceed 12 puffs per day.
Is ipratropium bromide inhaler safe to take if I'm pregnant or breastfeeding?
Studies of ipratropium in animals have not demonstrated negative effects on the fetus. There have been no studies in humans.
It is not known if ipratropium is secreted in breast milk. Other medications in the same class of drugs are secreted into breast milk. It is not known whether the small amounts that may appear in the milk are of any consequence to the infant.
What else should I know about ipratropium bromide inhaler?
What preparations of ipratropium bromide inhaler are available?
Nasal Inhaler: 0.03 or 0.06%. Oral Inhaler (aerosol): 0.021 mg/spray
How should I keep ipratropium bromide inhaler stored?
Ipratropium should be kept at room temperature, 15 C-30 C (59 F-86 F). Excessive humidity should be avoided.
Reference: FDA Prescribing Information
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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Asthma OverviewAsthma is a condition in which hyperreactive airways constrict and result in symptoms like wheezing, coughing, and shortness of breath. Causes of asthma include genetics, environmental factors, personal history of allergies, and other factors. Asthma is diagnosed by a physician based on a patient's family history and results from lung function tests and other exams. Inhaled corticosteroids (ICS) and long-acting bronchodilators (LABAs) are used in the treatment of asthma. Generally, the prognosis for a patient with asthma is good. Exposure to allergens found on farms may protect against asthma symptoms.
Asthma SlideshowWhat is asthma? Learn about asthma, a chronic inflammation disorder of the bronchiole tubes (airways). Discover information about an asthma attack, asthma symptoms, prevention and treatments such as asthma medications and inhalers.
Bronchitis PictureAcute bronchitis usually comes on quickly and gets better after several weeks. See a picture of Acute Bronchitis and learn more about the health topic.
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Chronic bronchitis is a cough that occurs daily with production of sputum that lasts for at least three months, two years in a row. Causes of chronic bronchitis include cigarette smoking, inhaled irritants, and underlying disease processes (such as asthma, or congestive heart failure). Symptoms include
- shortness of breath, and
Treatments include bronchodilators and steroids. Complications of chronic bronchitis include COPD and emphysema.
Chronic cough is a cough that does not go away and is generally a symptom of another disorder such as
- allergic rhinitis,
- sinus infection,
- cigarette smoking,
- postnasal drip,
- medications, and
- less frequently tumors or other lung disease. Treatment of chronic cough is dependent upon the cause.
Chronic cough treatment is based on the cause, but may be soothed natural and home remedies.
Chronic rhinitis and post-nasal drip symptoms include:
- An itchy, runny nose
- Itchy ears, eyes, and throat
Seasonal allergic rhinitis (also called hay fever) usually is caused by pollen in the air. Perennial allergic rhinitis is a type of chronic rhinitis and is a yearâ€“round problem, often caused by indoor allergens, such as dust, animal dander, and pollens that may exist at the time. Treatment of chronic rhinitis and post nasal drip are dependent upon the type of rhinitis condition.
Cold & Flu QuizAches? Pain? Fever? This Cold & Flu Quiz tests your knowledge on the difference between coming down with the common cold and sickness from influenza virus.
Common ColdThe common cold (viral upper respiratory tract infection) is a contagious illness that may be caused by various viruses. Symptoms include a stuffy nose, headache, cough, sore throat, and maybe a fever. Antibiotics have no effect upon the common cold, and there is no evidence that zinc and vitamin C are effective treatments.
COPD (Chronic Obstructive Pulmonary Disease)
COPD or chronic obstructive pulmonary disease is a lung condition caused by smoking tobacco, exposure to secondhand smoke, and/or air pollutants. Conditions that accompany COPD include:
- Chronic bronchitis
- Chronic cough
Symptoms of COPD include:
- Shortness of breath
- Chronic cough
Treatment of COPD include smoking cessation, medications, and surgery. The life expectancy of a person with COPD depends on the stage of the disease.
Take the COPD QuizCOPD is a combination of three conditions? Take this quiz to learn the three conditions that make up the pulmonary disease called chronic obstructive pulmonary disease (COPD).
Emphysema (Lung Condition)Emphysema is a COPD (chronic obstructive pulmonary disease) that often occurs with other obstructive pulmonary problems and chronic bronchitis. Causes of emphysema include chronic cigarette smoking, exposure to secondhand smoke, air pollution, and in the underdeveloped parts of the world. Symptoms of emphysema include chronic cough, chest discomfort, breathlessness, and wheezing. Treatments include medication and lifestyle changes.
Hay FeverHay fever (allergic rhinitis) is an irritation of the nose caused by pollen and is associated with the following allergic symptoms: nasal congestion, runny nose, sneezing, eye and nose itching, and tearing eyes. Avoidance of known allergens is the recommended treatment, but if this is not possible, antihistamines, decongestants, and nasal sprays may help alleviate symptoms.
How to Stop Coughing
Coughing is a reflex that helps a person clear their airways of irritants. There are many causes of an excessive or severe cough including:
- Irritants like
- cigarette and secondhand smoke
- air fresheners
- Medications like beta blockers and ACE inhibitors
- Medical conditions like
- the common cold
- lung cancer
- heart disease
Natural and home remedies that help cure and soothe a cough are:
Natural and home remedies to help cure and soothe a cough are:
- Stay hydrated
- Gargle saltwater
- Use cough drops or lozenges
- Use herbs and supplements like ginger, mint, licorice, and slippery elm
- Don't smoke
Over-the-counter products (OTC)to cure and soothe a cough include
- cough suppressants and expectorants, and
- anti-reflux drugs.
Prescription drugs that help cure a cough include
- narcotic medications,
- inhaled steroids, and
- anti-reflux drugs like proton pump inhibitors or PPIs, for example,
- omeprazole (Prilosec),
- rabeprazole (Aciphex), and
- pantoprazole (Protonix).
- Irritants like
Natural Cold & Flu RemediesWhat natural remedies work for the flu and common cold? Many claim cold symptoms and flu symptoms can be relieved with Echinacea, zinc, neti pots, garlic, vitamin C, saltwater gargles, nasal strips, or bed rest. Find out what cold and flu treatments work the natural way, and what doesn't.
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