- Side Effects
- Drug Interactions
- Pregnancy & Breastfeeding
- What Else to Know
Generic Name: ipratropium bromide
Brand Names: Atrovent HFA, Atrovent
Drug Class: Anticholinergics, Respiratory
What is ipratropium bromide inhaler, and what is it used for?
Ipratropium bromide is a bronchodilator that dilates (enlarges) airways (bronchi) in the lungs. It is used in treating, symptoms of asthma, colds, allergies, and chronic obstructive pulmonary disease (COPD) due to emphysema or chronic bronchitis.
Ipratropium blocks the effect of acetylcholine on airways (bronchi) and nasal passages. Acetylcholine is a chemical that nerves use to communicate with muscle cells. In asthma and chronic obstructive pulmonary disease, cholinergic nerves going to the lungs cause the narrowing of the airways by stimulating muscles surrounding the airways to contract.
The "anti-cholinergic" effect of ipratropium blocks the effect of cholinergic nerves, causing the muscles to relax and the airways to dilate. Mucus glands in the nose also are controlled by nerves that use acetylcholine to communicate. By blocking acetylcholine, ipratropium helps relieve symptoms of allergies and the common cold by preventing secretion of mucus by mucus glands in the nose. When inhaled, ipratropium travels directly to the airways, and very little is absorbed into the body.
The FDA approved ipratropium in October 1995.
What are the side effects of ipratropium bromide?
The most common side effects associated with ipratropium are:
Ipratropium can cause bronchospasms that can be life-threatening. It can also cause rash, itching, or serious allergic reactions involving closure of the airways.
Because of its anticholinergic effect it may worsen symptoms of benign prostatic hyperplasia and narrow-angle glaucoma.
What is the dosage for ipratropium bromide?
- The recommended dose for allergies is 2 sprays (0.03%) in each nostril 2 or 3 times daily.
- The dose for treating symptoms of the common cold is 2 sprays (0.06%) in each nostril 3 to 4 times daily.
- The dose for treating asthma is 8 inhalations every 20 minutes as needed for up to 3 hours.
- The dose for treating bronchospasms associated with COPD is 2 puffs 4 times daily and additional puffs if needed but not to exceed 12 puffs per day.
Which drugs interact with ipratropium bromide?
Pregnancy and breastfeeding
- Studies of ipratropium in animals have not demonstrated negative effects on the fetus. There have been no studies in humans.
- It is not known if ipratropium is secreted in breast milk. Other medications in the same class of drugs are secreted into breast milk. It is not known whether the small amounts that may appear in the milk are of any consequence to the infant.
What else should I know about ipratropium bromide?
What preparations of ipratropium bromide inhaler are available?
- Nasal Inhaler: 0.03 or 0.06%. Oral Inhaler (aerosol): 0.021 mg/spray
How should I keep ipratropium bromide inhaler stored?
- Ipratropium should be kept at room temperature, 15 C-30 C (59 F-86 F). Excessive humidity should be avoided.
Ipratropium bromide inhaler is a medication prescribed for the treatment of allergic or nonallergic rhinitis and rhinitis due to the common cold. Oral ipratropium is prescribed for the treatment of acute asthma flares and bronchospasms that result from COPD (chronic obstructive pulmonary disease) and emphysema. The most common side effects associated with ipratropium are dry mouth, cough, headache, nausea, dizziness, and difficulty breathing.
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Chronic Rhinitis and Post-Nasal Drip
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COPD (Chronic Obstructive Pulmonary Disease)
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COPD vs. Emphysema
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Hay Fever (Allergic Rhinitis)
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Asthma Over-the-Counter Treatment
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Can Asthma Damage Your Lungs?
Asthma inflames the inner lining of the respiratory tubes and tightens the smooth muscles surrounding the airways, and can cause irreversible damage to your lungs if the condition is not controlled well.
What Is the Treatment for Asthmatic Bronchitis?
Asthmatic bronchitis refers to inflammation of the bronchial tubes carrying air inside the lungs that occurs because of asthma. Treatment for asthmatic bronchitis involves bronchodilators, steroids, treating secretions, leukotriene inhibitors, antibiotics, oxygen administration and avoiding triggers.
How Long Do COPD Exacerbations Last?
Chronic obstructive pulmonary disease (COPD) exacerbations may last for two days or even two weeks, depending on the severity of the symptoms.
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What Is Bronchiectasis?
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How Long Does Asthmatic Bronchitis Last?
The duration of the disease usually depends on the patient’s overall health and age. In patients with acute bronchitis symptoms may last less than 10 days. In patients with severe asthmatic bronchitis, the symptoms are recurrent and usually last between 30 days to even 2 years with flares and remissions.
Asthma in Children
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Is It OK to Drink Alcohol With COPD?
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What are the Four Stages of COPD?
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Can You Have Emphysema Without COPD?
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Can Asthma Go Away on Its Own?
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Occupational asthma is a type of asthma caused by exposure to a substance in the workplace. Symptoms and signs include wheezing, chest tightness, and shortness of breath. The usual treatment for occupational asthma involves removal from exposure and the use of bronchodilators and inhaled anti-inflammatory medicines.
What Are the Symptoms of Eosinophilic Asthma?
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What Is the Main Cause of Bronchial Asthma?
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Can You Exercise With Exercise-Induced Asthma?
You can continue exercise and normal physical activity even after being diagnosed with exercise-induced asthma (EIA).
What Are the Four Types of Asthma?
Asthma is a chronic inflammatory disease of the airways (bronchi). Bronchi generally allow for the passage of air in and out of the lungs. In asthma, these airways develop hypersensitivity, inflammation, and narrowing. This causes difficulty in breathing. The four types are mild intermittent, mild persistent, moderate persistent, and severe persistent.
Can Someone with COPD Still Have Sex?
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Can Asthma Be Genetic?
While asthma genes are inherited in families, the risks of developing the condition are half due to genetic susceptibility and half due to environmental factors.
Can People With COPD Get Better?
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What Are the Symptoms of E-Asthma?
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COPD is caused by long-term exposure to things that irritate the airways, such as smoking.
What Is the End-of-Life Care for COPD?
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What Is the Best Treatment for Asthma?
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What Should COPD Patients Avoid?
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How Do You Know if Your Baby Has Asthma?
Properly diagnosing and managing asthma in babies and young children can be challenging. However, be on the lookout for these signs and symptoms.
How Do COPD Patients Cope With Shortness of Breath?
Episodes of shortness of breath or breathlessness occur in individuals with severe conditions, such as chronic obstructive pulmonary disease (COPD). An episode of breathlessness could be predicted if triggers are known, and it becomes highly unpredictable if triggers are unknown.
How Does Asthma Start?
Though asthma symptoms may come on suddenly without any prior noticeable change, sometimes, an asthma attack typically starts with a few early warning signs.
How Do You Know if You Have Asthma or Not?
Your doctor may diagnose you with asthma based upon your signs and symptoms and after performing a physical exam and certain tests.
What Does Daliresp Do for COPD?
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What Is Severe Asthma?
Asthma is a chronic inflammatory lung disease caused due to the airway’s hypersensitive response to allergic stimuli. Severe asthma or status asthmaticus is defined as asthma that is uncontrolled, despite adherence with maximal optimized therapy and treatment of contributory factors or asthma that worsens when high dose treatment is decreased.
What Class Is Severe Asthma?
Asthma is termed as a chronic inflammatory lung disease caused by the airway’s hypersensitive response to allergic stimuli (dust, pollen, pollution, smoke or unhygienic conditions). This results in the narrowing of airway passages, making it hard to breathe. It is often genetic and passed down from families and precipitated during childhood.
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Prevention & Wellness
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