- What is INTERFERON BETA 1-B-INJECTION, and how does it work (mechanism of action)?
- Is INTERFERON BETA 1-B-INJECTION available as a generic drug?
- Do I need a prescription for INTERFERON BETA 1-B-INJECTION?
- What are the uses for INTERFERON BETA 1-B-INJECTION?
- What are the side effects of INTERFERON BETA 1-B-INJECTION?
- What is the dosage for INTERFERON BETA 1-B-INJECTION?
- Which drugs or supplements interact with INTERFERON BETA 1-B-INJECTION?
- Is INTERFERON BETA 1-B-INJECTION safe to take if I'm pregnant or breastfeeding?
- What else should I know about INTERFERON BETA 1-B-INJECTION?
What is INTERFERON BETA 1-B-INJECTION, and how does it work (mechanism of action)?
- Interferon beta-1b is a protein produced by recombinant DNA technology using E. coli bacteria into which the human interferon beta genes have been introduced. It is used for treating multiple sclerosis (MS). Interferon beta has antiviral properties and plays a role in regulating the immune response. The exact mechanism by which interferon beta-1b works in the body to treat MS is not known. Interferon beta-1b does not cure MS. Rather, it helps to decrease the number of flare-ups and slows the occurrence of some of the physical disability that commonly occurs in the disease.
- Interferon beta-1b was approved by the FDA in July, 1993.
What are the uses for INTERFERON BETA 1-B-INJECTION?
What are the side effects of INTERFERON BETA 1-B-INJECTION?
Common side effects include:
- Injection site reactions
- Lymphopenia (reduced number of white blood cells)
- Flu-like symptoms
- Muscle pain
- Increased liver enzymes
- Abdominal pain
- Stomach pain
Other side effects include:
Quick GuideMultiple Sclerosis (MS) Symptoms and Treatment
What is the dosage for INTERFERON BETA 1-B-INJECTION?
- The recommended dose is 0.25 mg every other day.
- Treatment is started at 0.0625 mg (0.25 mL) every other day, and increased over a six-week period to reach the target dose of 0.25 mg every other day.
Which drugs or supplements interact with INTERFERON BETA 1-B-INJECTION?
Combining interferon beta-1b with zidovudine (Retrovir) may increase blood levels of zidovudine and the risk of bone marrow suppression.
Is INTERFERON BETA 1-B-INJECTION safe to take if I'm pregnant or breastfeeding?
- Use of interferon beta-1b has not been adequately evaluated in pregnant women. Due to the lack of conclusive safety data, interferon beta-1b should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus.
- It is not known if interferon beta-1b is excreted in breast milk. As many drugs enter breast milk and can potentially cause harm to the nursing infant, interferon beta-1b should be used cautiously in nursing mothers.
What else should I know about INTERFERON BETA 1-B-INJECTION?
What preparations of INTERFERON BETA 1-B-INJECTION are available?
Powder for injection (single use vial): 0.3 mg/vial
How should I keep INTERFERON BETA 1-B-INJECTION stored?
- Preferably interferon beta-1b should be stored at room temperature, 68 F to 77 F (20 C to 25 C).
- It may be stored at 59 F to 86 F (15 C to 30 C) for up to 3 months.
- After dilution, it should be used immediately or refrigerated and used within 3 hours.
Interferon beta-1b injection (Betaseron, Extavia) is a drug prescribed to treat relapsing forms of multiple sclerosis. It also reduces MS flares. Side Effects, drug interactions, recommended dosages, storage information, and pregnancy and breastfeeding information should be reviewed prior to using any medication.
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Alternative Therapy for Multiple SclerosisThe term alternative therapy, in general, is used to describe any medical treatment or intervention that has not been scientifically documented or identified as safe or effective for a specific condition. Alternative therapy encompasses a variety of disciplines that range from diet and exercise to mental conditioning to lifestyle changes.
Biologics Biologic Drug Class
A biologic drug is a product that is produced from living organisms or contain components of living organisms. Biologics include recombinant proteins, tissues, genes, allergens, cells, blood components, blood, and vaccines. Biologics are used to treat numerous disease and conditions, for example:
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interferonInterferons are a family of natural occurring proteins. Interferons are used to treat many diseases that involve the immune system for example, cancers, hepatitis, AIDS, multiple sclerosis (MS), genital and perianal warts, and granulomatous disease. Side effects, drug interactions, warnings and precautions and patient safety information should be reviewed prior to taking any medication.
INTERFERON BETA 1A-INJECTION
Avonex (interferon beta 1a injection) is an injection medication prescribed to treat relapsing forms of multiple sclerosis (MS) in adults. Common side effects include:
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Multiple Sclerosis (MS)Multiple sclerosis or MS is an autoimmune disorder in which brain and spinal cord nerve cells become demyelinated. This damage results in symptoms that may include numbness, weakness, vertigo, paralysis, and involuntary muscle contractions. Different forms of MS can follow variable courses from relatively benign to life-threatening. MS is treated with disease-modifying therapies. Some MS symptoms can be treated with medications.
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Women who are pregnant and have multiple sclerosis may have more difficulty carrying a pregnancy. Multiple sclerosis does not affect ability to conceive, and does not seem to affect fertility. MS symptoms during pregnancy may stay the same or get better; however, they may worsen after giving birth. Pregnancy decreases the number of relapses, but flares increase in the first 3-6 months after delivery. Pregnant women with MS may carrying a pregnancy more difficult to tell when labor starts, and there is an increased need to use forceps or vacuum to assist with delivery or b7 C-section (Cesarean birth) increases.
Some treatment MS drugs may be safe to use during pregnancy; however, some drugs should not be taken, for example, baclofen (Gablofen, Lioresal), fluoxetine (Prozac, Sarafem), or solifenacin succinate (VESIcare), and most disease-modifying therapies (DMTs).
Talk with your healthcare team about vitamins, supplements, and medications that you are taking if you are pregnant and have MS.
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