Picture of Squamous Cell Carcinoma with Central Hyperkeratosis
Squamous cell carcinoma. A round nodule with central hyperkeratosis, firm and indolent. This lesion cannot be distinguished clinically from keratoacanthoma; it is easily distinguished from nodular BCC because BCC does not develop hyperkeratosis.
Image Source: Fitzpatrick's Color Atlas & Synopsis of Clinical Dermatology
Klaus Wolff, Richard Allen Johnson, Dick Suurmond
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Text: WebMD Medical Reference