Picture of Erythema Multiforme 3

The type of bulla that may occur in erythema multiforme is shown here. Mucosal lesions are not uncommon. Erythema multiforme is a self-healing disease, with an average duration of about 2 weeks. Herpes simplex infection is by far the most common etiologic agent. Finally, a wide variety of drugs, most commonly the sulfonamides, may cause this syndrome.