Hypoparathyroidism: Symptoms & Signs

Medically Reviewed on 7/25/2020

Hypoparathyroidism is a condition in which the parathyroid glands produce too little levels of hormone known as parathormone. This in turn leads to an abnormal lowering of calcium levels in the blood.

Signs and symptoms of hypoparathyroidism include

  • tingling or burning in the fingertips, toes, and lips;
  • muscle aches or cramps in the legs, feet, stomach, or face;
  • muscle twitching or spasms particularly around the mouth; and
  • fatigue or weakness.

Other associated signs and symptoms can include

Causes of hypoparathyroidism

Hypoparathyroidism has several different causes. It may be caused by a birth defect, an autoimmune disease, or due to removal of the parathyroid glands during thyroid surgery.

Other hypoparathyroidism symptoms and signs

  • Brittle Nails
  • Cataracts of the Eyes
  • Dry, Coarse Skin
  • Fatigue or Weakness
  • Memory Loss
  • Muscle Aches or Cramps in the Legs, Feet, Stomach, or Face
  • Muscle Twitching or Spasms Particularly Around the Mouth
  • Patchy Hair Loss
  • Tingling or Burning in the Fingertips, Toes, and Lips
  • Tooth Problems


Where is the thyroid gland located? See Answer

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Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.