- What is hyoscyamine sublingual, and how does it work (mechanism of action)?
- What are the uses for hyoscyamine sublingual?
- What are the side effects of hyoscyamine sublingual?
- What is the dosage for hyoscyamine sublingual?
- Which drugs or supplements interact with hyoscyamine sublingual?
- Is hyoscyamine sublingual safe to take if I'm pregnant or breastfeeding?
- What else should I know about hyoscyamine sublingual?
What is hyoscyamine sublingual, and how does it work (mechanism of action)?
- Hyoscyamine is an anticholinergic drug used for treating irritable bowel syndrome, peptic ulcer disease, hypermotility of the lower urinary tract, and gastrointestinal disorders.
- Anticholinergics work by blocking the action of acetylcholine in the brain and at nerves throughout the body. Acetylcholine is a neurotransmitter. Neurotransmitters are chemicals made and released by nerves that travel to nearby nerves or, in the case of acetylcholine, nearby muscles and glands where they attach to receptors on the surface of the nerve, muscle or glandular cells.
- The attachment of the neurotransmitter can stimulate or inhibit the activity of the receptor-containing cells. Anticholinergic drugs like hyoscyamine affect the function of many organs by preventing acetylcholine from binding to its receptors.
- Hyoscyamine decreases the activity of muscles in the intestine and lower urinary tract. It reduces the production of sweat, saliva, digestive juices, urine, and tears. It also reduces the production of bronchial secretions.
What brand names are available for hyoscyamine sublingual?
Levbid, Levsin, Nulev, Anaspaz
Is hyoscyamine sublingual available as a generic drug?
Yes
Do I need a prescription for hyoscyamine sublingual?
Yes
What are the uses for hyoscyamine sublingual?
Hyoscyamine is used for treating
- irritable bowel syndrome (IBS),
- peptic ulcer disease (stomach ulcers),
- hypermotility of the lower urinary tract, and
- gastrointestinal disorders.
What are the side effects of hyoscyamine sublingual?
Side effects include:
- Xerostomia
- Dry eyes
- Urinary retention
- Constipation
- Confusion
- Impaired memory
- Excitement
- Nervousness
Other side effects include:
- Decreased sweating (anhidrosis)
- Flushing
- Blurred vision
- Dilation of the pupil of the eye (mydriasis)
- Loss of taste
- Weakness
- Fever
- Impotence
- Nausea
- Vomiting
- Headache
- Dizziness
- Ataxia
- Drowsiness
- Stomach pain
- Itching
- Allergic reactions
Possible serious side effects include:
- Palpitations
- Increased heart rate
- Heat stroke
- Hallucinations
- Increased ocular pressure
- Psychosis
QUESTION
What is irritable bowel syndrome or IBS? See AnswerWhat is the dosage for hyoscyamine sublingual?
- The recommended oral dose of immediate release tablet or drops for treating irritable bowel syndrome, gastrointestinal disorders, or peptic ulcer disease is 0.125 mg to 0.25 mg every 4 hours.
- The maximum dose is 1.5 mg daily.
- The dose of immediate release formulations for treating hypermotility disorder is 0.15 to 0.3 mg orally every 6 hours.
Which drugs or supplements interact with hyoscyamine sublingual?
- The risk of adverse effects increases when hyoscyamine is combined with other drugs that block the action of acetylcholine. Such drugs include antimuscarinics, amantadine, haloperidol, phenothiazines, monoamine oxidase (MAO) inhibitors, tricyclic antidepressants, or some antihistamines.
- Antacids may interfere with the absorption of extended release hyoscyamine.
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Is hyoscyamine sublingual safe to take if I'm pregnant or breastfeeding?
- It is not known whether hyoscyamine can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. It should only be given to pregnant women when it is clearly needed.
- Hyoscyamine is excreted in breast milk.
What else should I know about hyoscyamine sublingual?
What preparations of hyoscyamine sublingual are available?
- Capsules or tablet Extended Release: 0.375 mg.
- Elixir: 0.125 mg/5 ml.
- Injections: 0.5 mg/ml.
- Oral Drops: 0.125 mg/ml.
- Tablet: 0.125 mg
How should I keep hyoscyamine sublingual stored?
- Hyoscyamine should be stored at room temperature between 20 C and 25 C (68 F and 77 F).
Summary
Hyoscyamine sublingual (Levbid, Levsin, Nulev, Anaspaz) is a prescription drug used to treat IBS (irritable bowel disease), stomach ulcers, hypermotility of the lower urinary tract, and GI disorders. Side effects may include dry eyes, constipation, confusion urinary retention, excitement. Drug interactions, dosage, and pregnancy and breastfeeding safety information should be reviewed prior to taking any medication.
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Irritable Bowel Syndrome (IBS)
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Top hyoscyamine-sublingual Related Articles
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Colic is crying or fussing that begins suddenly, lasting for a total of three hours a day and happening more than three days a week for about three weeks. Symptoms include the baby's face turning red, the belly is distended, the feet may be cold, the hands clenched, and the legs may alternate between being flexed or extended. Treatment may involve ruling out other causes of the fussing and the doctor prescribing anti-gas bubbly medicine.Diarrhea
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IBS-D or irritable bowel syndrome with diarrhea refers to IBS with diarrhea. Symptoms of IBS-D include
- intestinal gas (flatulence),
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- frequent stools,
- abdominal pain,
- diarrhea, and
- nausea.
New non-FDA approved IBS tests may help diagnose IBS and IBS-D. Treatment of IBS-D is geared to toward managing symptoms with diet, medication, and lifestyle changes.
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What are symptoms of irritable bowel syndrome (IBS)? Take this quiz and get quick facts on causes and treatment options for this common and uncomfortable digestive disorder.Nerve Disease and Bladder Control
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Parkinson's disease is a slowly progressive neurological disease characterized by a fixed inexpressive face, a tremor at rest, slowing of voluntary movements, a gait with short accelerating steps, peculiar posture and muscle weakness, caused by degeneration of an area of the brain called the basal ganglia, and by low production of the neurotransmitter dopamine. Most patients are over 50, but at least 10 percent are under 40.Peptic Ulcer (Stomach Ulcer)
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A hole in the lining of the stomach, duodenum, or esophagus. See a picture of Peptic Ulcer and learn more about the health topic.Ulcerative Colitis
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Urinary Incontinence in Children
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