- Hydroxyapatite Crystals
What is hydroxyapatite crystal deposition disease?
What are hydroxyapatite crystals?
Hydroxyapatite molecules can group together (crystallize) to form microscopic clumps, called hydroxyapatite crystals.
Tiny crystals of hydroxyapatite sometimes form in or around joints and can cause inflammation of joints and tissues around the joints, such as tendons and ligaments. They have been described particularly as a cause of rotator cuff inflammation of the shoulder.
The inflammation caused by hydroxyapatite crystals has been referred to as hydroxyapatite crystal disease.
What causes hydroxyapatite crystal deposition disease?
While not fully understood, the cause of hydroxyapatite crystal disease is believed to be due to the accumulation of small calcium phosphate crystals in the joint tissue.
These crystals may accumulate due to several factors, such as:
Is hydroxyapatite crystal deposition disease the same as gout or pseudogout?
No. These conditions are similar in that they are all caused by the inflammation that results from the body's reaction to crystals. However, hydroxyapatite crystals are distinctly different from the crystals of pseudogout or gout. While hydroxyapatite crystals can sometimes also be found in the company of the calcium pyrophosphate crystals characteristic of pseudogout, these are quite different types of crystals.
What are the symptoms of hydroxyapatite crystal deposition disease?
Hydroxyapatite crystal disease (HACD) symptoms vary depending on the location of crystal buildup and the severity.
Common symptoms of HACD may include:
- Limited range of motion
- Popping or clicking sounds
Diagnosis of hydroxyapatite crystal deposition disease
Sometimes, hydroxyapatite crystals can be seen clumped in the fluid of a joint that has developed arthritis. The crystals are usually so small as to be invisible under a regular microscope and thus require a special (electron) microscope for identification.
What is the treatment for hydroxyapatite crystal deposition disease?
The treatment of the inflammation caused by hydroxyapatite crystals includes rest, cold application, and medications to reduce inflammation. Cortisone-related medications injected into inflamed tissues can also sometimes help decrease inflammation and thereby relieve pain.
Garcia GM, McCord GC, Kumar R. "Hydroxyapatite crystal deposition disease." National Center for Biotechnology Information.
Top Hydroxyapatite Related Articles
Cortisone InjectionCortisone injections are used to treat small areas of inflammation or widespread inflammation throughout the body. There is minimal pain from these injections, and relief from the pain of inflammation occurs rapidly.
GoutBuildup of uric acid crystals in a joint causes gouty arthritis. Symptoms and signs include joint pain, swelling, heat, and redness, typically of a single joint. Gout may be treated with diet and lifestyle changes, as well as medication.
Gout Diet Foods MenuWhether you get gout can depend on your diet. Some foods like red meat, alcohol, and high-fructose corn syrup in sodas can raise your risks. But other foods can reduce gout attacks. Limiting foods that cause gout in your diet can protect you from this painful joint condition, a type of arthritis.
Gout PictureCondition characterized by abnormally elevated levels of uric acid in the blood, recurring attacks of joint inflammation (arthritis), deposits of hard lumps of uric acid in and around the joints, and decreased kidney function and kidney stones. See a picture of Gout and learn more about the health topic.
Gout SlideshowGout attacks (gouty arthritis) are caused by crystals of uric acid deposits. Learn about symptoms, causes, treatments and medication for this painful condition.
Gout QuizLearn what causes those painful crystals to form during a gout flare. Take the Gout Quiz to learn all about this painful arthritic condition.
Is Coffee Good for Gout?Moderate coffee consumption may lower your risk of developing gout and reduce the chances of having a flare-up. Coffee contains beneficial compounds such as caffeine and polyphenols which can lower uric acid levels in the body.
Joint Aspiration (Arthrocentesis)Joint aspiration (arthrocentesis) is a procedure where fluid is drained from a joint with a needle and syringe for laboratory analysis. This may help determine the causes of joint swelling or arthritis.
PseudogoutPseudogout, a form of arthritis, results when deposits of crystals collect in and around the joints. Symptoms of pseudogout include pain, stiffness, warmth, and joint swelling of the knees, ankles, hips, shoulders, and/or wrists. Treatment for pseudogout aims to decrease inflammation through the use of nonsteroidal anti-inflammatory drugs, ice, and rest.
Rotator Cuff Tear and InjuryRotator cuff injury is damage to any of the four tendons that stabilize the shoulder joint. Shoulder pain and tenderness are common symptoms. Rotator cuff disease treatment depends on the severity of the shoulder injury.
Shoulder BursitisShoulder bursitis is inflammation of the shoulder bursa. Bursitis may be caused by injury, infection, or a rheumatic condition. Symptoms include pain, swelling, tenderness, and pain with movement of the shoulder joint. Treatment may involve ice compresses, rest, and anti-inflammatory medications and depends on whether there is an infection.
What Foods Get Rid of Gout?A gout diet may help decrease uric acid levels in the blood. A gout diet isn't a cure. But it may lower the risk of recurring gout attacks and slow the progression of joint damage.
What Is the Best Thing to Drink If You Have Gout?Here are 8 ideal drink options for people with gout, which include drinking more water, coffee, low-fat milk, wine, and green tea.
What Is the Fastest Way to Get Rid of Gout?Gout is a common and complex type of arthritis that can affect anyone, but it is most commonly observed in men. It's characterized by sudden flares of joint pain, swelling, redness, and tenderness in the joints, often at the base of the big toe. Gout symptoms may come and go, but there are ways to manage symptoms and prevent flares.