- What Kind of Doctor Do I Need? Slideshow
- Dental (Oral) Health Quiz
- Causes of a Heart Attack Slideshow
- What is Cyanokit (hydroxocobalamin)?
- What are the uses for Cyanokit (hydroxocobalamin)?
- What are the side effects of Cyanokit (hydroxocobalamin)?
- What is the dosage for Cyanokit (hydroxocobalamin)?
- Which drugs or supplements interact with Cyanokit (hydroxocobalamin)?
- Is Cyanokit (hydroxocobalamin) safe to use during pregnancy or while breastfeeding?
- What else should I know about Cyanokit (hydroxocobalamin)?
What is Cyanokit (hydroxocobalamin)?
Cyanokit is an injectable drug that reverses the effect of cyanide. It is an antidote used for treating cyanide poisoning. Cyanide is an extremely toxic poison. Cyanide poisoning can kill within minutes because it prevents cells in the body from using oxygen.
What brand names are available for Cyanokit (hydroxocobalamin)?
- Cyanokit is the brand name available for hydroxocobalamin injection.
- Alpharedisol and Hydroxomin are brand names that have been discontinued and are no longer available in the US.
Is Cyanokit (hydroxocobalamin) available as a generic drug?
Do I need a prescription for Cyanokit (hydroxocobalamin)?
What are the uses for Cyanokit (hydroxocobalamin)?
- Cyanokit is an antidote for cyanide toxicity. It is used for treating people with known or suspected cyanide poisoning.
What are the side effects of Cyanokit (hydroxocobalamin)?
- Red colored urine (chromaturia)
- Decreased white blood cells
- Infusion site reactions
Other side effects include:
- Eye swelling, irritation, redness
- Difficulty swallowing (dysphagia)
- Abdominal discomfort
- Indigestion (dyspepsia)
- Peripheral edema
- Chest discomfort
- Allergic reaction
- Memory impairment
- Shortness of breath (dyspnea)
- Throat tightness and dry throat
- Hot flush
- Increased sun sensitivity (photosenstivity)
- Possible serious side effects include:
- Serious allergic reactions
- High blood pressure
- Abnormal heartbeats
What is the dosage for Cyanokit (hydroxocobalamin)?
- The recommended initial dose is 5 g (one vial) administered by intravenous infusion over 15 minutes.
- A second 5 g dose may be administered if the response is not adequate.
- The maximum total dose is 10 g.
Which drugs or supplements interact with Cyanokit (hydroxocobalamin)?
- Cyanokit drug interaction studies have not been conducted.
Latest MedicineNet News
Daily Health News
Is Cyanokit (hydroxocobalamin) safe to use during pregnancy or while breastfeeding?
What else should I know about Cyanokit (hydroxocobalamin)?
What preparations of Cyanokit (hydroxocobalamin) are available?
- Powder for Injection: 5 g/vial
How should I keep Cyanokit (hydroxocobalamin) stored?
- Powder should be stored at room temperature, 15 C to 30 C (59 F to 86 F).
- After mixing with liquid it may be stored for up to 6 hours at a temperature not exceeding 40 C (104 F).
- It should not be frozen, and any unused portion should be discarded after 6 hours.
How does Cyanokit (hydroxocobalamin) work?
- Hydroxocobalamin is made up off cyanocobalamin (vitamin B12) attached to cobalt. Hydroxocobalamin reverses the action of cyanide by binding to cyanide molecules. Each hydroxocobalamin molecule binds to one cyanide ion. The result of the chemical reaction is inactivation of cyanide and release of cyanocobalamin which is then excreted in the urine.
Cyanokit (hydroxocobalamin injection) is a prescription drug that is an antidote for cyanide toxicity. Side effects include vomiting, diarrhea, chest discomfort, headache, difficulty breathing, and difficulty swallowing.
Multimedia: Slideshows, Images & Quizzes
Trauma and First Aid Quiz: Training and Supplies
What should be in your first-aid kit? Take this quiz to understand trauma and learn the truth about how to administer first aid.
First Aid Quiz: Care for Wounds, Scrapes, Cuts, and Burns
Wound care for cuts and scrapes includes treatment to clean and bandage the injury. Should you use alcohol, hydrogen peroxide,...
Related Disease Conditions
Cancer is a disease caused by an abnormal growth of cells, also called malignancy. It is a group of 100 different diseases, and is not contagious. Cancer can be treated through chemotherapy, a treatment of drugs that destroy cancer cells.
Hypoxia is a condition in which the normal concentration of oxygen in the blood is not enough for normal life functions. Symptoms of hypoxia and/or hypoxemia may be acute such as fast heart rate, rapid breathing, and shortness of breath; or severe symptoms include confusion, the inability to communicate, coma, and sometimes death. Treatment of hypoxia and/or hypoxemia is to provide supplemental oxygen to the body as soon as possible.
Peripheral neuropathy is a problem with the functioning of the nerves outside of the spinal cord. Symptoms may include numbness, weakness, burning pain (especially at night), and loss of reflexes. Possible causes may include carpel tunnel syndrome, shingles, vitamin or nutritional deficiencies, and illnesses like diabetes, syphilis, AIDS, and kidney failure. Peripheral neuropathy is diagnosed with exams and tests. Treatment for the condition depends on the cause. Usually, the prognosis for peripheral neuropathy is good if the cause can be successfully treated or prevented.
Mercury is a naturally occurring element found in water, soil, and the air. Mercury also is contained in some fish, some of the products we use in the home, school, or dentist. Mercury poisoning can cause cognitive problems, dermatitis, tremor and other symptoms. Information about sources of mercury exposure, potential health effects, symptoms of exposure, fish that may contain mercury, consumer products that contain mercury, and ways to reduce your exposure to mercury is important for the health of you, and your family.
Arsenic comes in two forms, inorganic and organic. Organic arsenic poisoning is usually not poisonous to humans; however, inorganic arsenic in large enough amounts can lead to shock and death. Symptoms of arsenic poisoning include nausea, abdominal pain, diarrhea, dehydration, dark urine, vertigo, delirium, shock, and death. Treatment for arsenic poisoning includes Hemodialysis and a variety of drugs.
Poison Control Centers
The United States National Poison Hotline is 1-800-222-1222. When you call this number you will be automatically linked to the nearest poison center in the United States. Call this number 24 hours a day, 7 days a week to talk to a poison expert.
Radon (A Citizen's Guide to Radon)
Radon is a radioactive gas that has been confirmed to cause cancers. About 21,000 individuals die each year due to radon exposure. Radon can be found in the ground, water supply, and the air you breathe. It is found in schools, homes, offices, and other buildings. You can purchase a Radon Test Kit and have the sample sent to the state radon office. Research has shown that the risk of lung cancer from breathing radon in air is much greater than the risk of stomach cancer from swallowing water with radon in it. The EPA offers a Consumers Guide to Radon Reduction so you can take action to reduce radon levels in your home, school, or office. Scientists are more certain about radon risks than from most other cancer-causing substances.
Lead-based paint and lead contaminated dust are the main sources of exposure for lead in U.S. children. Lead-based paints were banned for use in housing in 1978. All houses built before 1978 are likely to contain some lead-based paint. However, it is the deterioration of this paint that causes a problem. Approximately 24 million housing units have deteriorated leaded paint and elevated levels of lead-contaminated house dust. More than 4 million of these dwellings are homes to one or more young children. Lead poisoning is entirely preventable. The key is stopping children from coming into contact with lead and treating children who have been poisoned by lead.
Treatment & Diagnosis
Medications & Supplements
Prevention & Wellness
Subscribe to MedicineNet's General Health Newsletter
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.