hydrocortisone valerate

What are the side effects of hydrocortisone valerate?

The most common side effects of hydrocortisone valerate are:

  • burning,
  • itching,
  • irritation, and
  • dryness at application sites.

Side effects are more frequent when occlusive dressings or large quantities are applied. Applying corticosteroids to infected skin may worsen the infection. Long-term use may lead to atrophy of the skin and pigmentation changes. Prolonged use of hydrocortisone can depress the ability of the body's adrenal glands to produce corticosteroids. Abruptly stopping hydrocortisone in these individuals can cause symptoms of corticosteroid insufficiency, along with:

Hydrocortisone valerate has produced mild, reversible suppression of corticosteroids in adult patients when administered for 5 days and the area was covered (occluded); when 15 grams was applied twice a day to over 25% to 60% body surface area; or when applied three times a day to over 20% to 30% body surface area for 3-4 weeks.

What is the dosage for hydrocortisone valerate?

Westcort should be applied sparingly to affected areas once or twice daily. The minimum effective amount should be used.

Which drugs or supplements interact with hydrocortisone valerate?

No significant drug interactions have been described with hydrocortisone valerate.


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Is hydrocortisone valerate safe to take if I'm pregnant or breastfeeding?

  • The use of hydrocortisone valerate in pregnant women has not been adequately evaluated.
  • It is not known if hydrocortisone valerate is secreted in breast milk.

What else should I know about hydrocortisone valerate?

What preparations of hydrocortisone valerate are available?

Cream or Ointment: 0.2%

How should I keep hydrocortisone valerate stored?

Westcort should be stored at room temperature, 59-86 F (15-30 C).


Hydrocortisone valerate is a corticosteroid that is used topically (on the skin) for the relief of inflammation and itching caused by a variety of skin conditions (for example, insect bites, eczema, and allergic reactions). Side effects include dryness, irritation, itching, and burning at the site of application. Drug interactions, dosing, and pregnancy and breastfeeding safety information should be reviewed prior to taking this medication.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Medically reviewed by John P. Cunha, DO, FACOEP; Board Certified Emergency Medicine


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