Cortenema (hydrocortisone enema)

Hydrocortisone enema is used rectally for the treatment of ulcerative proctitis, inflamed hemorrhoids, and anal itching, burning, and inflammation caused by several conditions that affect the anal area.

What brand names are available for hydrocortisone enema?

Cortenema

Is hydrocortisone enema available as a generic drug?

Yes

Do I need a prescription for hydrocortisone enema?

Yes

Side effects of hydrocortisone enema include:

• Local pain
• Burning
• Rectal bleeding

Other side effects include:

• Allergic reaction
• Reduced wound healing
• Vertigo
• Headache

Possible serious side effects include:

• High blood pressure
• Fluid retention
• Heart failure
• Sodium retention
• Low potassium
• Peptic ulcer
• Increased risk of diabetes
• Adrenal insufficiency
• Growth suppression in children

For proctitis the usual dosage is one enema applied at bedtime for 21 days or until symptoms resolve.

The risk of drug interactions from hydrocortisone enema is low because it is administered rectally.

• Hydrocortisone enema has not been adequately evaluated during pregnancy. Hydrocortisone enema taken orally can appear in breast milk, and can have adverse effects on the baby.
• It is not known whether hydrocortisone administered rectally is absorbed in sufficient amounts to appear in breast milk.

What preparations of hydrocortisone enema are available?

Enema: 100 mg/60 ml

How should I keep hydrocortisone enema stored?

Hydrocortisone enema should be stored at room temperature, 20 C to 25 C (68 F to 77 F).