- What is hydrocortisone-rectal foam, and how does it work (mechanism of action)?
- What brand names are available for hydrocortisone-rectal foam?
- Is hydrocortisone-rectal foam available as a generic drug?
- Do I need a prescription for hydrocortisone-rectal foam?
- What are the uses for hydrocortisone-rectal foam?
- What are the side effects of hydrocortisone-rectal foam?
- What is the dosage for hydrocortisone-rectal foam?
- Which drugs or supplements interact with hydrocortisone-rectal foam?
- What else should I know about hydrocortisone-rectal foam?
What is hydrocortisone-rectal foam, and how does it work (mechanism of action)?
Hydrocortisone is a natural corticosteroid produced by the adrenal glands that are located adjacent to the kidneys. Corticosteroids have potent anti-inflammatory properties and are used in a wide variety of inflammatory conditions such as arthritis, colitis, asthma, bronchitis, certain skin rashes, and allergic or inflammatory conditions of the nose and eyes. There are numerous preparations of corticosteroids including oral tablets, capsules, liquids, topical creams and gels, inhalers and eye drops, as well as injectable and intravenous solutions. Hydrocortisone that is used for rectal conditions is discussed in this article. The FDA approved hydrocortisone in December 1952.
What brand names are available for hydrocortisone-rectal foam?
Cortifoam, Anusol-HC, Anucort-HC, Proctocort, Colocort, Cortenema, Hemmorex-HC
What are the uses for hydrocortisone-rectal foam?
What are the side effects of hydrocortisone-rectal foam?
Hydrocortisone's most common side effects when applied to the rectum include:
- include burning,
- contact dermatitis,
- secondary infections, and
- lightening of skin color (hypopigmentation)
Other side effects include:
- local pain and
- rectal bleeding
What is the dosage for hydrocortisone-rectal foam?
For proctitis the usual dosage is one suppository applied in the morning and night time. Severe cases may require application 3 times daily or 2 suppositories twice daily. One enema is applied at bedtime for 21 days or until symptoms resolve. The dosing for foam is one applicator once daily or every 12 hours for 2-3 weeks, then every other day if necessary.
Which drugs or supplements interact with hydrocortisone-rectal foam?
The risk of drug interactions is low when hydrocortisone is administered rectally.
What else should I know about hydrocortisone-rectal foam?
What preparations of hydrocortisone-rectal foam are available?
Enema: 100 mg/60 ml; Foam: 10% (15 g); Suppository: 25 and 30 mg
How should I keep hydrocortisone-rectal foam stored?
Hydrocortisone should be store at room temperature, 20 C to 25 C (68 F to 77 F), in a sealed container.
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hydrocortisone rectal foam (Cortifoam, Anusol-HC, Anucort-HC, Proctocort, Colocort, Cortenema, Hemmorex-HC) is a medication used to treat ulcerative proctitis, hemorrhoids, anal itching, burning, and inflammation. Side effects, drug interactions, and pregnancy safety information should be reviewed prior to using this medication.
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Hemorrhoids (piles) are swollen veins in the rectum and anus. Causes include pregnancy, obesity, diarrhea, low-fiber diet, and prolonged sitting on the toilet. Treatment varies depending upon the severity of the hemorrhoids. Some treatment options include over-the-counter creams and suppositories, stool softeners, warm sitz baths, and hemorrhoidectomies.
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Anal itching is the irritation of the skin at the exit of the rectum, known as the anus, accompanied by the desire to scratch. Causes include everything from irritating foods we eat, to certain diseases, and infections. Treatment options include over-the-counter medications, using moist pads, and gentle cleaning and drying of the anus.
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REFERENCE: FDA Prescribing Information.