Generic Name: hydrocodone
Brand Name: Zohydro ER
Drug Class: Opioid Analgesics
What is hydrocodone, and what is it used for?
Hydrocodone is an opioid narcotic pain-reliever similar to oxycodone, morphine, methadone, fentanyl, and other opioids.Hydrocodone is prescribed for the long-term treatment of severe pain for which other treatment options are not effective, not tolerated, or would most likely not be strong enough to adequately manage the pain.
Hydrocodone, like other opioids, stimulates receptors on nerves in the brain to increase the threshold to pain (the amount of stimulation it takes to feel pain) and reduce the perception of pain (the perceived importance of the pain). Unlike other hydrocodone products such as Vicodin which contain acetaminophen, Zohydro ER contains only hydrocodone.The FDA approved Zohydro in October 2013.
What are the side effects of hydrocodone?
The most frequent adverse reactions include:
Other side effects include:
- Spasm of the ureter, which can lead to difficulty in urinating.
Other patient warnings include:
- Hydrocodone can impair thinking and the physical abilities required for driving or operating machinery.
- Hydrocodone can depress breathing, and should be used with caution in elderly, debilitated patients, and in patients with serious lung disease.
- Hydrocodone is habit forming. Mental and physical dependence can occur when used long-term.
What is the dosage for hydrocodone?
- The initial dose for adults is 10 mg orally every 12 hours.
- The dose may be increased every 3 to 7 days by 10 mg every 12 hours as needed to control pain.
- Capsules must be swallowed whole and not chewed.
Pregnancy and breastfeeding
- There are no adequate studies of hydrocodone in pregnant women.
- Hydrocodone is excreted in breast milk, and, therefore should be used cautiously by nursing mothers.
What else should I know about hydrocodone?
What preparations of hydrocodone (Zohydro ER) are available?
- Capsules (Extended Release): 10, 15, 20, 30, 40, and 50 mg
How should I keep hydrocodone (Zohydro ER) stored?
- Hydrocodone should be stored at room temperature, between 15 C and 30 C (59 F and 86 F).
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Hydrocodone is a narcotic pain reliever prescribed for the relief moderate to severe pain. Common side effects include vomiting, nausea, dizziness, and lightheadednes. Consult your doctor if pregnant or breastfeeding.
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Related Disease Conditions
Gallbladder pain (often misspelled "gall bladder") is generally produced by of five problems, biliary colic, cholecystitis, gallstones, and pancreatitis. Causes of gallbladder pain include intermittent blockage of ducts by gallstones or gallstone inflammation and/or sludge that also may involve irritation or infection of surrounding tissues, or when a bile duct is completely blocked. Treatment of gallbladder depends on the cause, which may include surgery.
Upper Respiratory Infection (URI)
An upper respiratory infection is a contagious infection of the structures of the upper respiratory tract, which includes the sinuses, nasal passages, pharynx, and larynx. Common causes of an upper respiratory infection include bacteria and viruses such as rhinoviruses, group A streptococci, influenza, respiratory syncytial, whooping cough, diphtheria, and Epstein-Barr. Examples of symptoms of upper respiratory infection include sneezing, sore throat, cough, fever, and nasal congestion. Treatment of upper respiratory infections are based upon the cause. Generally, viral infections are treated symptomatically with over-the-counter (OTC) medication and home remedies.
Kidney pain has a variety of causes and symptoms. Infection, injury, trauma, bleeding disorders, kidney stones, and less common conditions may lead to kidney pain. Symptoms associated with kidney pain may include fever, vomiting, nausea, flank pain, and painful urination. Treatment of kidney pain depends on the cause of the pain.
The common cold (viral upper respiratory tract infection) is a contagious illness that may be caused by various viruses. Symptoms include a stuffy nose, headache, cough, sore throat, and maybe a fever. Antibiotics have no effect upon the common cold, and there is no evidence that zinc and vitamin C are effective treatments.
Tailbone Pain (Coccydynia)
Coccydynia is an inflammation of the bony area (tailbone or coccyx) located between the buttocks. Coccydynia is associated with pain and tenderness at the tip of the tailbone between the buttocks. Pain is often worsened by sitting. There are many causes of tailbone pain that can mimic coccydynia including fracture, pilonidal cysts, infection, and sciatica. Treatment methods include medication and rest.
Lower Back Pain (Lumbar Spine Pain)
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Shoulder and Neck Pain
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Chronic cough is a cough that does not go away and is generally a symptom of another disorder such as asthma, allergic rhinitis, sinus infection, cigarette smoking, GERD, postnasal drip, bronchitis, pneumonia, medications, and less frequently tumors or other lung disease. Chronic cough treatment is based on the cause, but may be soothed natural and home remedies.
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Neck Pain (Cervical Pain)
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The shoulder is the most often dislocated joint in the body due to its mobility. A dislocation occurs when the head of the humerus is dislocated from its socket. Symptoms and signs of a shoulder dislocation include nausea and vomiting, lightheadedness, weakness, and sweating. There are various methods of reducing a dislocation and returning the humeral head to its normal place. The method for reduction of a shoulder dislocation depends upon the type of dislocation, the patient, the situation, and the clinician's experience. Intravenous narcotics and muscle relaxants are often administered to relax the muscles and relieve pain.
Ankle Pain (Tendonitis)
Ankle pain is commonly due to a sprain or tendinitis. The severity of ankle sprains ranges from mild (which can resolve within 24 hours) to severe (which can require surgical repair). Tendinitis of the ankle can be caused by trauma or inflammation.
Elbow pain is most often the result of tendinitis, which can affect the inner or outer elbow. Treatment includes ice, rest, and medication for inflammation. Inflammation, redness, warmth, swelling, tenderness, and decreased range of motion are other symptoms associated with elbow pain. Treatment for elbow pain depends upon the nature of the patient's underlying disease or condition.
Arthritis, bursitis, IT band syndrome, fracture, and strain are just some of the causes of hip pain. Associated symptoms and signs include swelling, tenderness, difficulty sleeping on the hip, and loss of range of motion of the hip. Treatment depends upon the cause of the hip pain but may include anti-inflammatory medications and icing and resting the hip joint.
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Emphysema, Chronic Bronchitis, and Colds
If you have a COPD such as emphysema, avoiding chronic bronchitis and colds is important to avoid a more severe respiratory infection such as pneumonia. Avoiding cigarette smoking, practice good hygeine, stay away from crowds, and alerting your healthcare provider if you have a sinus infection or cold or cough that becomes worse. Treatment options depend upon the severity of the emphysema, bronchitis, or cold combination.
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Treatment & Diagnosis
- Complex Regional Pain Syndrome (CRPS)
- Chronic Pain
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Medications & Supplements
- Oxycodone for Pain (OxyContin, Roxicodone, Oxecta, Oxaydo, Xtampza ER, Roxybond)
- hydrocodone and ibuprofen, Vicoprofen
- OTC Pain Relievers and Fever Reducers
- chlorpheniramine and hydrocodone, Tussionex, TussiCaps, Tussionex Pennkinetic, Vituz
- Can Botulinum Toxin Be Used for Pain Relief?
- hydrocodone/homatropine (Tussigon)
- What Are Opioid Equivalents and Conversions?
- Tussigon (hydrocodone)
- Pain Medications (Narcotics)
- Side Effects of Vicodin (hydrocodone/acetaminophen)
- Olinvyk (oliceridine)
- Side Effects of Tussionex (chlorpheniramine and hydrocodone)
- Zohydro ER (hydrocodone)
Prevention & Wellness
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
FDA Prescribing Information.