How Many Different Types of Carcinomas Are There? 6 Types

1. Basal cell carcinoma (BCC)

Basal cell carcinoma is a type of skin cancer that occurs in the deepest cell layer of the top layer of the skin. It is the most common type of skin cancer in the United States. Basal cell carcinoma rarely spreads to other parts of the body.

Causes

The primary cause of BCC is overexposure to ultraviolet radiation in the form of sunlight or tanning beds. Some factors that can increase the risk of getting BCC include:

• Treatment of psoriasis
• Weak immune system
• History of skin cancer
• Advanced age
• Male gender
• Exposure to certain chemicals
• Radiation exposure
• Long-term skin inflammation or injury
• Fair skin

Symptoms

Symptoms of basal cell carcinoma include:

• Scaly, red patches
• Sores that do not heal
• Shiny bumps or lumps
• Raised scar-like areas
• Pink growths

2. Squamous cell carcinoma (SCC)

Squamous cell carcinoma is the second most common type of skin cancer. It can also be found in the cell linings of the:

• Digestive tract
• Respiratory tract
• Certain organs

SCC commonly affects the areas of the body that are exposed to the sun, such as the:

• Face
• Back of the hands
• Lips
• Ears
• Neck

Overexposure to the sun is the most common cause of SCC. These carcinomas tend to grow and spread rapidly, unlike BCC.

Causes

Factors that can increase the risk of developing SCC include:

• Male gender
• Human papillomavirus infection
• Smoking
• Advanced age
• Radiation exposure
• Exposure to certain chemicals
• Excessive exposure to ultraviolet radiation (sunlight or tanning beds)
• History of skin cancer
• Weak immune system
• Psoriasis treatment
• Long-term skin inflammation or injury
• Fair skin

Symptoms

Symptoms of squamous cell carcinoma include:

• Sores that do not heal
• Firm, red bump on sun-exposed skin that does not go away
• Skin growth that looks like warts
• Thickened skin on the lower lip that occurs due to smoking or chewing tobacco
• Patch of skin that feels scaly, bleeds, or develops a crust
• Spots that resemble age spots

3. Adenocarcinoma

Adenocarcinoma starts in the glands that line certain internal organs and releases substances such as digestive juices and mucus. Adenocarcinomas may occur in the:

• Breast
• Lung
• Colon
• Stomach
• Prostate
• Pancreas
• Esophagus

Causes 

The most common causes of adenocarcinoma include:

• Smoking
• Toxin exposure
• Previous radiation therapy

Symptoms

Symptoms of adenocarcinoma vary depending on the area of the body affected.

• Prostate cancer:
  • Blood in the urine
  • Erectile dysfunction
  • Frequent urination
• Breast cancer:
  • Breast swelling
  • Change in breast shape and size
  • Red or flaky skin
  • Bloody fluid leaking from the nipple
  • Dimpled or uneven skin
• Colorectal cancer:
  • Blood stools
  • Abdominal pain
  • Diarrhea
  • Constipation
  • Gas or bloating
  • Unexplained weight loss
• Pancreatic cancer: 
  • Abdominal pain
  • Weight loss
  • Heartburn
  • Nausea and vomiting
  • Feeling bloated
  • Loss of appetite
  • Back pain
  • Floating stool
• Lung cancer:
  • Chronic cough with mucus and blood
  • Difficulty breathing
  • Chest pain
  • Wheezing
  • Hoarseness
  • Loss of appetite
  • Weight loss

4. Ductal carcinoma in situ (DCIS)

DCIS is the earliest type of breast cancer and forms in the inner lining of the breast ducts. As these cancers have not spread to the surrounding tissue, survival rates are higher.

Causes

• Obesity
• Genetics
• Early menstruation
• Dense breasts
• Not breastfeeding
• Not having children
• Lack of exercise
• Pregnancy after age 30
• Previous radiation therapy
• Advanced age (over 50)

Symptoms

• Lumps in the breast
• Discharge from the nipple

5. Renal cell carcinoma

Renal cell carcinoma is the most common type of kidney cancer that grows as a single tumor within the kidney. Renal cell carcinoma is usually identified in a computed tomography scan or ultrasound or when the tumors have become extremely large.

Causes

Factors that may increase the risk of developing renal cell carcinoma include:

• Smoking
• Obesity
• Hypertension
• Family history of kidney cancer
• Exposure to trichloroethylene
• Advanced kidney cancer
• African American ethnicity
• Increased acetaminophen use
• Certain conditions

Symptoms

Symptoms may appear in the advanced stages and include:

• Loss of appetite
• Unexplained weight loss
• Pain in one side of the body
• Blood in the urine
• Anemia
• Lump in the abdomen

6. Merkel cell carcinoma

Merkel cell carcinoma is commonly found on or just beneath the skin and in hair follicles. The cancer cells grow and spread rapidly to other parts of the body.

Causes

Risk factors associated with Merkel cell carcinoma include:

• Fair skin type
• Advanced age (over 65)
• Overexposure to the sun
• Weak immune system

Symptoms

Warning signs of Merkel cell carcinoma include:

• Painless, shiny lumps
• Red, pink lumps

Treatment for carcinoma may vary depending on the type, location, and extent of the disease. Options may include:

• Surgery: Removal of the cancerous tissue with some surrounding tissue and an ideal option for long-term survival in the early stages.
• Radiation therapy: Uses high-energy radiation to kill cancerous cells and may be used in combination with surgery or chemotherapy for best results.
• Chemotherapy: Uses drugs that target and eliminate cancerous cells.

Other options include immunotherapy, hormonal therapy, specialized treatment (such as photodynamic therapy, cryosurgery, Mohs surgery, targeted therapy, and chemical peels).