- How It Works
- When to Call a Doctor
Angio-seal is a bioabsorbable medical device used to reduce bleeding in patients who have undergone angiographic or interventional procedures. Angio-seal dissolves in the body in approximately 60-90 days.
What is Angio-Seal used for?
Angio-Seal vascular closure is used to reduce bleeding at the femoral arterial puncture site (arteriotomy) in patients who have undergone the following:
- Diagnostic angiography
- Endovascular procedures
- Interventional procedures such as:
- Cardiac catheterization (a procedure to examine various functions of the heart through the insertion of a catheter)
- Coronary angioplasty or percutaneous coronary intervention (a procedure to widen blocked or narrowed coronary arteries)
- Neuroangiography or cerebral angiography (a procedure that uses a special dye and X-rays to analyze blood flow through the brain)
Certain factors lead to a risk of complications after these surgical procedures, such as:
How does Angio-Seal work?
Angio-Seal is used immediately after the catheter is removed. Bioabsorbable components that are responsible for sealing the artery (with a minimum diameter of 4 mm) include:
- Anchor: An intra-arterial dissolvable component is inserted in the vessel wall or artery with the help of an insertion sheath, an arteriotomy locator (modified dilator), and a guide wire.
- Sponge: An absorbable collagen is placed on the outer side of the artery. This plug is sandwiched between the arterial wall and puncture site by traction.
- Absorbable positioning Dexon suture or a stitch: This helps clinch the anchor and sponge or collagen together to form a seal, which stops bleeding and promotes the artery healing process.
The implanted device gets absorbed by the body and takes up to 90 days to dissolve, which can be confirmed by an ultrasound.
What are the advantages of Angio-Seal?
Angio-Seal is an implantable device that has been increasingly used as an alternative to manual compression because it appears to:
- Reduce time to ambulate
- Facilitate rapid hemostasis
- Improve patient comfort
- Be comparatively cost-effective
- Be safe and efficient
- Decreased the time needed for complete bed rest
- Help in quick recovery
Different brands of Angio-Seal available include:
- Angio-Seal VIP
- Angio-Seal EVOLUTION
- CELT ACD
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What complications are associated with vascular closure devices?
The risk-to-benefit ratio usually favors the use of vascular closure devices in potentially fatal or lifestyle-limiting cardiac disease in certain patients. The majority of complications occur within the first 30 days after the procedure and may include:
- Hematoma formation (abnormal accumulation of blood outside of a blood vessel)
- Arterial thrombosis (arterial blood clot)
- Pseudoaneurysm (piercing the wall of a blood vessel due to an artery injury)
- Intravenous fistula formation (abnormal connection between an artery and a vein)
- Rectal peritoneal hemorrhage
- Arterial limb ischemia
- Vessel occlusion
- Distal emboli
- Deep vein thrombosis
- Nerve injury
When to contact a doctor
Patients should consult their doctor immediately if they notice the following symptoms:
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Delayed Complication from a Percutaneous Vascular Closure Device Following a Neuro-Interventional Procedure NIH: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296513/
Initial experience with Angioseal: Safety and efficacy of the endovascular closure device NIH: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777322/
Failure of Closure Device Agency for Healthcare Research and Quality: https://psnet.ahrq.gov/web-mm/coming-undone-failure-closure-device
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Cardiac CatheterizationCardiac Catheterization is an invasive imaging procedure used to evaluate patients at risk of or suffering from heart disease. Other interventional or therapeutic procedures may be performed during cardiac catheterization. Cardiac catheterization in general is a safe procedure; however, examples of risks include: blood clots, abnormal heart rhythms, infection, stroke, or heart attack. The results of the procedure will determine follow-up treatment or procedures.
Percutaneous Coronary Intervention (PCI)Balloon angioplasty of the coronary artery and stents (percutaneous coronary intervention, PCI) is a nonsurgical procedure that relieves narrowing and obstruction of the arteries to the muscle of the heart. PCI can relieve chest pain (angina), minimize or stop a heart attack, or improve the prognosis of patients with unstable angina. The availability of stainless steel stents has expanded the spectrum of patients suitable for PCI.
Heart disease (coronary artery disease) occurs when plaque builds up in the coronary arteries, the vessels that supply blood to the heart. Heart disease can lead to heart attack. Risk factors for heart disease include:
- High blood pressure
- High cholesterol
- Family history
Angina, shortness of breath, and sweating are just a few symptoms that may indicate a heart attack. Treatment of heart disease involves control of heart disease risk factors through lifestyle changes, medications, and/or stenting or bypass surgery. Heart disease can be prevented by controlling heart disease risk factors.
HematomaA hematoma is a collection of blood that is outside a blood vessel. There are different areas where hematomas occur including; inside the skull, on the scalp, ears, septum, bones, finger nails, toenails, and intra-abdominal.
How Is a CT Coronary Angiography Done?Coronary computerized tomography angiography (CCTA) is a heart scan or imaging test that helps diagnose plaque buildup and consequent narrowing of the coronary arteries. The procedure is performed to diagnose many heart conditions, including coronary artery disease (CAD), narrowing of the existing stent, and evaluation of coronary bypass graft patency. CCTA is not invasive and has fewer complications and faster recovery compared to other imaging studies.
How Is a Pulmonary Angiography Done?A pulmonary angiography detects problems in the blood flow of the pulmonary vessels. The results of the procedure are shown as a moving X-ray known as a pulmonary angiogram. Doctors need to insert a catheter into your arm or groin and thread it through your veins to your heart as part of the procedure.
Peripheral Vascular DiseasePeripheral vascular disease (PVD) refers to diseases of the blood vessels (arteries and veins) located outside the heart and brain. While there are many causes of peripheral vascular disease, doctors commonly use the term peripheral vascular disease to refer to peripheral artery disease (peripheral arterial disease, PAD), a condition that develops when the arteries that supply blood to the internal organs, arms, and legs become completely or partially blocked as a result of atherosclerosis. Peripheral artery disease symptoms include intermittent leg pain while walking, leg pain at rest, numbness in the legs or feet, and poor wound healing in the legs or feet. Treatment for peripheral artery disease include lifestyle measures, medication, angioplasty, and surgery.
Vascular DiseaseVascular disease includes any condition that affects your circulatory system. Vascular disease ranges from diseases of your arteries, veins and lymph vessels to blood disorders that affect circulation.
What Are Human Blood Vessels?Blood vessels are small tube-like structures through which blood circulates throughout the human body. The blood vessels transport oxygen and nutrients to the tissues and organs and remove carbon dioxide and waste away from the tissues and organs.