How Is Necrotizing Pancreatitis Treated?

Necrotizing pancreatitis is a severe inflammation of the pancreas, causing tissue death. If the dead tissue gets infected, it can cause severe complications, such as peritonitis (inflammation of the abdominal cavity), septic shock, and multiorgan dysfunction syndrome.

The main symptom of necrotizing pancreatitis is abdominal pain. A person may feel abdominal pain in several places, including:

• At the front of the abdomen
• Near the stomach
• Around the back

10 other symptoms of necrotizing pancreatitis

1. Fever
2. Nausea
3. Vomiting
4. Swollen abdomen
5. Dehydration
6. Low blood pressure
7. Rapid heart rate
8. Chills
9. Shortness of breath
10. Jaundice (yellow tint of the skin or eyes)

Necrotizing pancreatitis may lead to a bacterial infection and sepsis if left untreated.

Sepsis is a condition where a person’s body reacts adversely to bacteria in their bloodstream, possibly causing the body to go into shock.

1. Necrotizing pancreatitis happens when the pancreas gets inflamed or injured, and the pancreatic enzymes leak. This harms the tissues of the pancreas. If this damage cannot be reversed, it causes necrotizing pancreatitis.
2. Necrotizing pancreatitis may start after an episode of sudden (acute) pancreatitis. People with chronic pancreatitis can get necrotizing pancreatitis, but this is not common.
3. Having gallstones.
4. Alcohol consumption.

8 other causes of necrotizing pancreatitis

1. Any physical injury to the pancreas
2. Pancreatic stone
3. Pancreatic tumor
4. High levels of calcium in the blood
5. Very high levels of blood fats (cholesterol)
6. Damage to the pancreas from medicines
7. Autoimmune diseases
8. Conditions that run in the family that harm the pancreas, such as cystic fibrosis

Infection can happen to the pancreas about two or three weeks after necrosis starts. This can lead to sepsis, a severe response to bacteria that can lead to shock. The shock damages organs, which ultimately leads to death.

Necrotizing pancreatitis is a potentially fatal disease and leads to serious complications in about 30 percent of patients. These include:

• Insufficient pancreatic enzymes (which can leave the patient unable to digest food)
• Organ failure
• Fistulae (abnormal holes in the walls of bodily structures)
• Internal bleeding
• Death

Besides necrotizing pancreatitis, acute pancreatitis can lead to several other life-threatening complications that include:

• Obstruction of the bile or pancreatic ducts
• Leakage from the pancreatic ducts
• Pseudocysts (fluid-filled cavities that may rupture, hemorrhage, or lead to infection)
• Damage to the pancreas
• Pleural effusion (fluid in the lungs)
• Splenic vein thrombosis

To diagnose necrotizing pancreatitis, a doctor may examine a person’s abdomen and analyze their history extensively. They may do blood tests to look for:

• Pancreatic enzyme level (amylase, lipase)
• Serum electrolytes
• Blood glucose
• Blood cholesterol
• Blood triglycerides
• Liver function tests

They may use the following tests to look at the pancreas:

• Abdominal ultrasound
• Computed tomography scan
• Magnetic resonance imaging

The doctor may do a biopsy to identify infection and tissue damage in the necrosed part.

Keeping the pancreas healthy can lower the risk of pancreatitis and help avoid complications, such as necrosis.

Pancreatitis cannot be prevented. However, certain lifestyle changes will help stay healthy and lower the risk, such as:

• Avoid drinking alcohol
• Do not smoke
• Stay at a healthy weight
• Eat a low-fat diet

It is essential to recognize the symptoms of necrotizing pancreatitis and speak to a doctor immediately. Getting the right diagnosis and treatment at the earliest is the best way to reduce complications.

Without treatment, necrotizing pancreatitis may lead to an infection or sepsis. This can lead to life-threatening organ damage.

Necrotizing pancreatitis is treatable. Treatments target pancreatitis and then, manage dead or infected tissue. With timely, proper treatment, a person who has had necrotizing pancreatitis should make a full recovery.

Making lifestyle changes to improve pancreatic health is the best way to avoid further problems.