What other names is Histidine known by?

Alpha-amino-4-imidazole propanoic acid, Histidina, L-2-Amino-3-(1H-imidazol-4-yl) propionic acid, L-Histidine, L-Histidine AKG, L-Histidine-Alpha Ketoglutaric Acid, L-Histidine HCl, Levo-Histidine.

What is Histidine?

Histidine is an amino acid. Amino acids are the building blocks of protein in our bodies. People use histidine as medicine.

Histidine is used for rheumatoid arthritis, allergic diseases, ulcers, and anemia caused by kidney failure or kidney dialysis.

Possibly Ineffective for...

Insufficient Evidence to Rate Effectiveness for...

  • Allergic diseases.
  • Ulcers.
  • Other conditions.
More evidence is needed to rate the effectiveness of histidine for these uses.

How does Histidine work?

Histidine is involved in a wide range of metabolic processes in the body.

Are there safety concerns?

Histidine might be safe for most people. Doses of up to 4 grams per day have been used in research without causing noticeable side effects.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of histidine during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Folic acid deficiency: If you have this condition, don't use histidine. It can cause an unwanted chemical called formiminoglutamic acid (FIGLU) to build up in the body.

Dosing considerations for Histidine.

The appropriate dose of histidine depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for histidine. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

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Last Editorial Review: 3/29/2011