Medical Definition of Hereditary kidney cancer

Reviewed on 3/29/2021

Hereditary kidney cancer: Kidney cancer due to a gene than can be transmitted from parent to child. The vast majority of kidney cancer cases are not hereditary, but a small proportion of renal cell cancers are caused by hereditary syndromes.

Among these syndromes are:

  • von Hippel-Lindau syndrome
  • Birt-Hogg-Dube syndrome
  • Hereditary papillary renal cell carcinoma

All of these syndromes are inherited in an autosomal dominant manner.

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