Hemolytic Uremic Syndrome (HUS): Symptoms & Signs

Medically Reviewed on 12/12/2019

Hemolytic uremic syndrome (HUS) is a condition in which there is destruction of red blood cells (hemolysis), low platelet count, and kidney failure. In hemolytic uremic syndrome, blood within the small blood vessels known as capillaries begins to clot abnormally. When red blood cells pass through the clogged capillaries, they are sheared apart and broken. Kidney failure (uremia) occurs when waste products build up in the bloodstream because the kidneys cannot filter and dispose of them.

Signs and symptoms associated with HUS include

Other symptoms and signs can occur, such as

Cause of hemolytic uremic syndrome

There are a number of possible causes of HUS, including E. coli infections, medications, pregnancy and the early postpartum period, AIDS, and Streptococcus pneumonia.

Other hemolytic uremic syndrome (hus) symptoms and signs


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Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.