Heartburn is an uncomfortable feeling of burning and warmth behind the breastbone (sternum) but sometimes rising as high as the neck. It usually occurs after meals, when lying down, or at night while sleeping. Heartburn usually is due to gastroesophageal reflux disease (GERD), the rise of stomach acid back up into the esophagus. Heartburn has nothing whatsoever to do with the heart though the discomfort of heartburn may be confused with heart pain and vice versa. Heartburn is a popular nonmedical term that often is referred to medically as pyrosis.
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.
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Examples of Medications for Heartburn
- Carafate (sucralfate)
- cimetidine, Tagamet HB
- esomeprazole (Nexium, Nexium 24HR, Nexium IV)
- famotidine, Pepcid, Pepcid AC
- metoclopramide, Reglan, Metozolv ODT, (Reglan ODT, Octamide, and Maxolon
- pantoprazole, Protonix
- Prilosec (omeprazole) vs. Nexium (esomeprazole)
- Proton Pump Inhibitors (PPIs) Drug Class
- rabeprazole, Aciphex
- ranitidine, Zantac
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