Heartburn is an uncomfortable feeling of burning and warmth behind the breastbone (sternum) but sometimes rising as high as the neck. It usually occurs after meals, when lying down, or at night while sleeping. Heartburn usually is due to gastroesophageal reflux disease (GERD), the rise of stomach acid back up into the esophagus. Heartburn has nothing whatsoever to do with the heart though the discomfort of heartburn may be confused with heart pain and vice versa. Heartburn is a popular nonmedical term that often is referred to medically as pyrosis.
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.
Pictures, Images, Illustrations & Quizzes
GERD Quiz: Test Your Digestive Diseases IQ
Who is at risk for developing GERD? Are you? Take this quiz to learn what GERD is, if you're at risk, and what you can do about...
Heartburn: Foods to Eat, Foods to Avoid
Learn the symptoms of heartburn and which foods cause heartburn or GERD. Discover home remedies and which foods may provide...
Picture of Gastroesophageal Reflux (GERD)
The stomach contents regurgitate and back up (reflux) into the esophagus The food in the stomach is partially digested by...
Causes of Heartburn
H. pylori (Helicobacter Pylori ) Infection Symptoms, Test, Treatment
Helicobacter pylori (H. pylori) is a bacteria that causes chronic inflammation (gastritis) of the inner lining of the stomach,...
19 Tips on How to Stop a Cough
Coughing is a reflex that helps a person clear their airways of irritants. There are many causes of an excessive or severe...
Angina (Symptoms, Causes, Types, Diagnosis, and Treatment)
Angina is chest pain due to inadequate blood supply to the heart. Angina symptoms may include chest tightness, burning,...
Chest pain is a common complaint by a patient in the ER. Causes of chest pain include broken or bruised ribs, pleurisy,...
Children's Cough Causes and Treatments
Children's cough causes include infection, acid reflux, asthma, allergies or sinus infection, whooping cough, and exposure to...
Cough (Chronic, Persistent Cough in Adults and Children)
Chronic cough is a cough that does not go away and is generally a symptom of another disorder such as asthma, allergic...
Gastroesophageal Junction Adenocarcinoma
Gastroesophageal junction adenocarcinoma is cancer that forms in the area where the esophagus joins the stomach. Having GERD and...
GERD (Acid Reflux, Heartburn)
GERD (gastroesophageal reflux disease) is a condition in which the acidified liquid contents of the stomach backs up into the...
Heart attack happens when a blood clot completely obstructs a coronary artery supplying blood to the heart muscle. A heart attack...
Heartburn (Acid Reflux) Symptoms, Relief Medicine, Cures
Heartburn is a burning sensation experienced from acid reflux (GERD). Symptoms of heartburn include chest pain, burning in the...
Hiatal Hernia (Symptoms, Diet, Surgery, Treatment)
Hiatal hernia is a condition in which a thin membrane of tissue connects the esophagus with the diaphragm becomes week, and a...
Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)
There are many types of pancreatic neuroendocrine tumors (NETs): gastrinoma, insulinoma, glucagonoma, VIPomas, and...
Scleroderma is an autoimmune disease of the connective tissue. It is characterized by the formation of scar tissue (fibrosis) in...
Smoking (How to Quit Smoking)
Smoking is an addiction. More than 430,000 deaths occur each year in the U.S. from smoking related illnesses. Secondhand smoke or...
Examples of Medications for Heartburn
- Carafate (sucralfate)
- cimetidine, Tagamet HB
- esomeprazole (Nexium, Nexium 24HR, Nexium IV)
- famotidine, Pepcid, Pepcid AC
- metoclopramide, Reglan, Metozolv ODT, (Reglan ODT, Octamide, and Maxolon
- pantoprazole, Protonix
- Prilosec (omeprazole) vs. Nexium (esomeprazole)
- Proton Pump Inhibitors (PPIs) Drug Class
- rabeprazole, Aciphex
- ranitidine, Zantac
Subscribe to MedicineNet's General Health Newsletter