- Side Effects
- Drug Interactions
- Pregnancy & Breastfeeding
- What Else to Know
Generic Name: guaifenesin and dextromethorphan hydrobromide
What is guaifenesin and dextromethorphan, and what is it used for?
Guaifenesin/dextromethorphan is a combination over-the-counter (OTC) medication that is an expectorant and cough suppressant used to temporarily relieve cough due to minor throat and bronchial irritations that are associated with the common cold. Guaifenesin/dextromethorphan also help loosen mucus and thin bronchial secretions.
What is the dosage for guaifenesin and dextromethorphan?
Adults and children 12 years of age and older:
- Robitussin DM and Robitussin DM Maximum Strength (liquid): Take 10 ml by mouth every 4 hours as needed. No more than 6 doses in 24 hours.
- Mucinex Fast-Max DM: Take 20 ml by mouth every 4 hours. No more than 6 doses in 24 hours.
- Robitussin DM Maximum Strength (capsules): Take 2 capsules by mouth every 4 hours as needed. No More than 12 capsules in 24 hours.
- Mucinex DM: Take 1 or 2 tablets by mouth every 12 hours. No more than 4 tablets in 24 hours.
- Mucinex DM Maximum Strength: Take 1 tablet by mouth every 12 hours. No more than 2 tablets in 24 hours.
Safe and effective use of guaifenesin and dextromethorphan is not established for children under 12 years of age.
What drugs interact with guaifenesin and dextromethorphan?
- Guaifenesin/dextromethorphan should not be used with MAO inhibitors like phenelzine (Nardil), selegiline (Zelapar, Emsam, and Eldepryl), tranylcypromine (Parnate), procarbazine (Matulane), rasagiline (Azilect) and isocarboxazid (Marplan). Such combinations increase the risk of serious side effects.
- Guaifenesin/dextromethorphan should not be used within 14 days of using a MAO inhibitor.
Is guaifenesin and dextromethorphan safe to use during pregnancy or while breastfeeding?
What else should I know about guaifenesin and dextromethorphan?
What preparations of guaifenesin and dextromethorphan are available?
Robitussin DM, Robitussin DM Maximum Strength, and Mucinex Fast-Max DM are available as oral liquid form.
- Robitussin DM contains 100 mg of guaifenesin and 10 mg of dextromethorphan in each 5 ml of liquid.
- Robitussin DM Maximum Strength and contains 400 mg of guaifenesin and 20 mg of dextromethorphan in each 10 ml of liquid.
- Robitussin DM Maximum Strength is available in 4 fluid ounce (120 ml) and 8 fluid ounce (240 ml) bottles. Mucinex Fast-Max DM is available in 6 fluid ounce (180 ml) bottles.
- Robitussin DM Maximum Strength is also available as liquid-filled capsules, containing 200 mg of guaifenesin and 10 mg of dextromethorphan in each capsule. Robitussin DM Maximum Strength is available in a package of 20 capsules.
- Mucinex Fast-Max DM contains 400 mg of guaifenesin and 20 mg of dextromethorphan in each 20 ml of liquid.
- Mucinex DM and Mucinex DM Maximum Strength are available as extended-release oral tablet form.
- Mucinex DM contains 600 mg of Guaifenesin and 30 mg of Dextromethorphan in each tablet, available as 20 tablets per package.
- Mucinex DM Maximum Strength contains 1200 mg of Guaifenesin and 60 mg of Dextromethorphan in each tablet, available as 14 tablets per package.
How should I keep Mucinex DM stored?
Store at room temperature between 15 C and 30 C (59 F and 86 F). Do not store liquid formulations in the refrigerator.
How does Mucinex DM work?
Guaifenesin is an expectorant, which works by thinning oral mucus and increasing mucus volume. Dextromethorphan works on the cough center in the brain. It disrupts sensitivity of cough receptors and interrupts transmission of cough impulses.
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Guaifenesin and dextromethorphan hydrobromide is an OTC used to temporarily relieve cough due to minor bronchial and throat irritation associated with the common cold. Side effects of guaifenesin and dextromethorphan are nausea, vomiting, constipation, drowsiness, and dizziness. Consult your doctor before taking if pregnant or breastfeeding.
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Cough: 19 Tips on How to Stop a Cough
Coughing is a reflex that helps a person clear their airways of irritants. There are many causes of an excessive or severe cough including irritants like cigarette and secondhand smoke, pollution, air fresheners, medications like beta blockers and ACE inhibitors, the common cold, GERD, lung cancer, and heart disease.Natural and home remedies to help cure and soothe a cough include staying hydrated, gargle salt water, use cough drops or lozenges, use herbs and supplements like ginger, mint, licorice, and slippery elm, and don't smoke. Over-the-counter products (OTC)to cure and soothe a cough include cough suppressants and expectorants, and anti-reflux drugs. Prescription drugs that help cure a cough include narcotic medications, antibiotics, inhaled steroids, and anti-reflux drugs like proton pump inhibitors or PPIs, for example, omeprazole (Prilosec), rabeprazole (Aciphex), and pantoprazole (Protonix).
What Is Mucus?
Mucus is a normal substance produced by lining tissues in the body. Excess mucus or mucus that is yellow, green, brown, or bloody may indicate a problem. Mucus production may increase when allergies, a cold, flu, cough, or sore throat are present. Antihistamines and cold and flu medications may help alleviate excess mucus. A neti pot may be used to decrease nasal congestion and clear mucus.
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Do Cold Sores Mean You Have an STD?
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Pimple vs. Cold Sore
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Cold Sores (Oral Herpes, Herpes Labialis)
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How Do You Get Rid of a Cold Overnight?
Cold symptoms are part of your body’s healing processes. Most of the time, it does not require any help. However, you can get rid of a cold faster, even overnight, by resting, drinking hot fluids, blowing your nose, gargling with salt water, taking a hot shower, using a humidifier and taking OTC pain relievers and decongestants.
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If you have a dry cough at night and in the morning, it could be due to a lingering cold or other viral infection. Learn about the potential causes of morning cough and how to manage your symptoms at home. Check out the center below for more medical references on cough relief, including multimedia (slideshows, images, and quizzes), related diseases, treatment, diagnosis, medications, and prevention or wellness.
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Whooping cough (pertussis) is a highly contagious respiratory infection caused by the bacteria Bordetella pertussis. There are an estimated 300,000 plus deaths annually from whooping cough (pertussis). Whooping cough commonly affects infants and young children but can be prevented with immunization with the vaccine. First stage whooping cough symptoms are a runny nose, sneezing, low-grade fever, a mild cough with the cough gradually becoming more severe. After one to two weeks, the second stage of whooping cough begins.
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How Can I Stop My Child From Coughing?
Treatment for cough is not recommended unless the cough interferes with the child’s sleep or activity or is accompanied by a fever. Different age groups of children require different therapies to stop them from coughing. Some good home remedies to treat cough in children include honey, warm milk, hydration, steam inhalation, resting, saline nose drops and other strategies.
Cold vs. Flu
Though the common cold and flu share many signs and symptoms, they are caused by different viruses. Signs and symptoms include sneezing, sore throat, runny nose, fatigue, and cough. Treatment options for the cold and flu are similar and focus on reducing symptoms. Doctors may prescribe antivirals/neuraminidase inhibitors for the flu.
Cold, Flu, Allergy Treatments
Before treating a cold, the flu, or allergies with over-the-counter (OTC) medications, it's important to know what's causing the symptoms, which symptoms one wishes to relieve, and the active ingredients in the OTC product. Taking products that only contain the medications needed for relieving your symptoms prevents ingestion of unnecessary medications and reduces the chances of side effects.
How Do I Get Rid of a Cold Sore Overnight?
You cannot get rid of cold sores overnight. There is no cure for cold sores. However, to speed up the healing time of a cold sore, you can consult with your doctor and take prescription medications such as antiviral tablets and creams. A cold sore may go away without treatment within a week or two.
What Part of the Body Loses the Most Heat in Cold Water?
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Genital Herpes and Cold Sores: 10 Myths and Facts
Genital herpes and cold sores (oral herpes) are the names given to two types of infection caused by the two types of herpes simplex virus (HSV): HSV-1 and HSV-2.
Children's Cough Causes and Treatments
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What Is the Fastest Way To Cure a Cough?
Learn what medical treatments can help ease your cough symptoms and speed up your recovery.
Sinus Infection vs. Cold
Viruses cause the common cold and most sinus infections. Bacterial and fungal infections may also cause a sinus infection. Signs and symptoms of colds and sinus infections include nasal irritation or dryness, sore throat, stuffy nose, nasal discharge/congestion, sneezing, and cough. Additional symptoms of sinus infections include sinus pressure behind the cheeks or eyes, facial pain when pressure is applied, bad breath, and thick yellow or green mucus. Treatment focuses on symptom relief.
What Are the 3 Stages of Whooping Cough?
The three stages of whooping cough include stage I (catarrhal), stage II (paroxysmal), and stage III (convalescent). Check out the center below for more medical references on whooping cough, including multimedia (slideshows, images, and quizzes), related disease conditions, treatment and diagnosis, medications, and prevention or wellness.
How Long Does Whooping Cough Last?
What is whooping cough and how long does whooping cough last? Learn more about whooping cough and how to recover from whooping cough.
Do Expectorants Make You Cough More?
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Is It a Cold or a Sinus Infection?
A sinus infection, also known as sinusitis or rhinosinusitis, is a condition in which the delicate membranes that line the sinuses may get swollen and become red. A cold or common cold is a viral infection. It affects the upper respiratory system, which includes the nose, mouth, throat, and lungs.
What Is the Best Treatment for Whooping Cough?
Learn what medical treatments can help ease your whooping cough symptoms and speed up your recovery.
What Can You Take for a Cold While Pregnant?
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How Serious Is Whooping Cough in Adults?
What is whooping cough (pertussis) and how serious is it for adults? Learn causes, symptoms and treatments.
How Long Is a Cold Sore Contagious?
Cold sores are blisters around your mouth and lips. Cold sores are contagious until they are completely healed.
Emphysema, Chronic Bronchitis, and Colds
If you have a COPD such as emphysema, avoiding chronic bronchitis and colds is important to avoid a more severe respiratory infection such as pneumonia. Avoiding cigarette smoking, practice good hygeine, stay away from crowds, and alerting your healthcare provider if you have a sinus infection or cold or cough that becomes worse. Treatment options depend upon the severity of the emphysema, bronchitis, or cold combination.
Is Whooping Cough (Pertussis) Contagious?
Whooping cough (pertussis) is a highly contagious respiratory infection caused by Bordetella pertussis. Whooping cough symptoms include severe coughing fits and whooping sound produced during inhalation. The bacteria spreads via airborne droplets produced during sneezing or coughing. There is a whooping cough vaccine that is typically administered during childhood vaccinations.
What Can Trigger a Cold Sore?
After you get infected with HSV, it lies inactively in the nerve cells inside your skin and may appear as another cold sore at the same place as before.
How Long Does a Cold Last?
Most often, a common cold lasts anywhere from 5 to 10 days in length.
How Do You Know If Your Child Has Whooping Cough?
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What Can I Do for My Baby’s Cough?
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How Do I Get Rid of My Toddler's Cough?
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What Do You Give a Child With a Cold?
Unfortunately, there is no cure for the common cold. Antibiotics may be used to fight bacterial infections, but they have no effect on viruses.
When to See a Doctor When Your Baby Has a Cold
If your baby has a cold, signs that it may be time to see a doctor include poor feeding, dehydration, breathing difficulties, ear pain, and more.
What Is Good for a Child's Cold?
The common cold is one of the main reasons for missing schools in children and missing work in adults. Children are affected more commonly with cold than adults, who may have an average of two to three colds each year.
How Do You Tell If Your Child Has Allergies or a Cold?
Colds and allergies have different causes, but both involve the body's immune system. Since the symptoms of allergies and the symptoms of a cold overlap, it can be hard to tell which one your child has.
How Do You Get a Cold Sore on Your Lip?
Cold sores, also called fever blisters or oral herpes, are a viral infection that leaves small blisters around your mouth. You get a cold sore on your lip due to viral infection from herpes simplex virus type 1 (HSV-1).
How to Identify Cold Symptoms in Children
When a child is sick, their way of showing it may not always be clear. Here’s what to look for to determine whether your child is sick with a cold.
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