Granulomatosis With Polyangiitis (GPA): Symptoms & Signs

Granulomatosis with polyangiitis (GPA) is an uncommon type of inflammation of small arteries and veins (vasculitis). GPA in its classic form involves inflammation of the arteries that supply blood to the tissues of the lungs, nasal passages, and kidneys, although other types of the condition can occur. In addition to the vasculitis, a specific type of inflammatory reaction occurs known as granuloma formation, when affected tissues are examined under the microscope.

Signs and symptoms of granulomatosis with polyangiitis include

• fatigue,
• weight loss,
• fevers,
• shortness of breath,
• joint pains, and
• bloody sputum.

Other possible associated symptoms and signs include

• pus-like drainage from the nose,
• nasal stuffiness,
• sinus infections and nosebleeds,
• coughing,
• blood in the urine,
• skin sores,
• bruising or rashes,
• eye redness, burning, or pain,
• vision problems,
• ear inflammation, or
• hearing problems.

Cause of granulomatosis with polyangiitis (GPA)

Doctors do not understand the exact cause of GPA.

Other granulomatosis with polyangiitis (gpa) symptoms

• Blood in the Urine
• Bloody Sputum
• Bruising or Rashes
• Coughing
• Ear Inflammation
• Eye Redness, Burning, or Pain
• Fatigue
• Fevers
• Hearing Problems
• Joint Pains
• Nasal Stuffiness
• Pus-Like Drainage From the Nose
• Shortness of Breath
• Sinus Infections and Nosebleeds
• Skin Sores
• Vision Problems
• Weight Loss

symptomchecker

Health concerns on your mind?
Click here to visit our Symptom Checker.

SLIDESHOW

What Is Rheumatoid Arthritis (RA)? Symptoms, Treatment, Diagnosis See Slideshow