Are There Gout Drugs Other than Indomethacin & Allopurinol?

  • Medical Editor: William C. Shiel Jr., MD, FACP, FACR
    William C. Shiel Jr., MD, FACP, FACR

    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Ask the experts

I have just had my first acute gout attack in my left wrist. The physician prescribed Indomethacin which took down the swelling, but when he put me on Allopurinol, I had to stop due to bad headaches and rashes. I now have a tophi on my wrist. Are there other long term drugs to reduce uric acid levels and clear the tophi? Will the tophi disappear with treatment?

Doctor's response

Yes, there are other long-term drugs that can be used to reduce uric acid levels and clear tophi.

Depending on your kidney function and history of kidney stones you might be a candidate for medications which can leach the uric acid from the body by increasing the excretion of uric acid through the kidney. These medications include probenecid (Benamid) and sulfinpyrazone (Anturane).

For more information, read our full medical article on gout.

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Reviewed on 1/11/2018