- Type 2 Diabetes: Learn the Warning Signs
- Diabetes Friendly Dining
- Type 2 Diabetes: Test Your Medical IQ
- What brand names are available for glimepiride?
- Is glimepiride available as a generic drug?
- Do I need a prescription for glimepiride?
- What are the uses for glimepiride?
- What are the side effects of glimepiride?
- What is the dosage for glimepiride?
- Which drugs or supplements interact with glimepiride?
- Is glimepiride safe to take if I'm pregnant or breastfeeding?
- What else should I know about glimepiride?
What are the uses for glimepiride?
What are the side effects of glimepiride?
Common side effects of glimepiride include:
Possible serious side effects of glimepiride include:
- Low blood platelets
- Low sodium
- Sensitivity to sunlight
- Liver dysfunction
- Serious allergic reactions
- Heart palpitations
- Numbness around the mouth
- Tingling in the fingers
- Muscle weakness
- Blurred vision
- Excessive yawning
- Loss of consciousness
Glimepiride is a derivative of a sulfonamide drug. People allergic to other sulfonamide-related drugs may develop an allergic reaction to glimepiride. Anyone who has an allergic reaction to sulfa drugs should not take glimepiride.
What is the dosage for glimepiride?
Like other medicines used to treat diabetes, the dose of glimepiride is individualized using periodic measurements of blood sugar to determine the best dose. The usual starting dose is 1 or 2 mg given orally once daily with breakfast or the first major meal of the day. The dose may be increased by 1-2 mg in 1-2 weeks interval up to 8mg maximum based on blood sugar response and given once daily.
Which drugs or supplements interact with glimepiride?
- Some medications when given with glimepiride may reduce its ability to lower blood sugar. These drugs include diuretics, for example, hydrochlorothiazide (Microzide, and many combinations with other drugs), loop diuretics (for example, furosemide [Lasix]), corticosteroids such as prednisone and methylprednisolone (Medrol), phenytoin (Dilantin), colesevelam (Welchol), danazol and somatropin (Genotropin). Rifampin increases the breakdown of glimepiride by liver enzymes. This might reduce the effect of glimepiride and result in higher levels of sugar in the blood.
- Beta blockers such as propranolol (Inderal) and atenolol (Tenormin) can cause low or high blood sugar. Additionally, they can directly reverse the sugar-lowering effect of sulfonylureas and render them less effective. Beta blockers also can blunt some of the body's protective responses to low blood sugar, thus making it difficult for patients to recognize reactions due to low blood sugar (hypoglycemia).
- Certain drugs when given with glimepiride may increase the risk of low blood sugar (hypoglycemia). These include nonsteroidal anti-inflammatory drugs or NSAIDs (for example ibuprofen), sulfa drugs, warfarin (Coumadin), miconazole (Oravig), fluconazole (Diflucan), chloramphenicol, cimetidine (Tagamet HB), ranitidine (Zantac), clarithromycin (Biaxin), MAO Inhibitors (for example, isocarboxazid [Marplan] and phenelzine [Nardil]), mifepristone (Mifeprex), probenecid, quinolone antibiotics and selective serotonin reuptake inhibitors or SSRIs (for example paroxetine [Paxil], fluoxetine [Prozac] and sertraline [Zoloft]) and voriconazole (Vfend). Blood sugar should be closely monitored when interacting drugs are given with glimepiride.
- Combination glimepiride with insulin and use in patients with congestive heart failure may increase risk of other heart related side effects.
Is glimepiride safe to take if I'm pregnant or breastfeeding?
- In animal studies, glimepiride and other sulfonylureas were associated with a higher risk of fetal death. However, there have been no good studies in women. Abnormal blood sugar concentrations (high or low) during pregnancy increase the risk of abnormalities in the fetus. Therefore, physicians must carefully weigh the benefits and risks of sulfonylurea treatment during pregnancy. Insulin is the drug of choice for treating diabetes in pregnant women.
- It is not known if glimepiride is excreted in breast milk like other sulfonylureas. Because of the risk of low blood sugar in the infant, it is recommended that glimepiride be discontinued in nursing mothers. If therapy other than diet and exercise is needed, insulin is preferred.
What else should I know about glimepiride?
What preparations of glimepiride are available?
Tablets: 1, 2, and 4 mg
How should I keep glimepiride stored?
Tablets should be stored at room temperature, between 15 C and 30 C (59 F and 86 F).
Latest Diabetes News
Daily Health News
Multimedia: Slideshows, Images & Quizzes
Type 2 Diabetes Diagnosis, Treatment, Medication
Learn about type 2 diabetes warning signs, symptoms, diagnosis, and treatment options. Read how diet and exercise can help manage...
Diabetes: What Raises and Lowers Your Blood Sugar Level?
Want to lower your blood sugar? Learn to better control your glucose levels by preventing blood sugar spikes and swings to avoid...
Diabetes Diet: Healthy Meal Plans for Diabetes-Friendly Eating
Discover the best and worst meals for diabetes-savvy dining. See how to avoid carbs and control your blood sugar with healthier...
Type 1 Diabetes: What Are The Symptoms?
What is type 1 diabetes? Is there a cure for type 1 diabetes? Learn about type 1 diabetes symptoms, warning signs, causes, and...
Diabetic Peripheral Neuropathy: Improve Diabetes Nerve Pain
Read about diabetic peripheral neuropathy and exercises to manage nerve pain. Learn how to cope with the symptoms of diabetic...
How Diabetes Can Affect Your Feet
Learn more about diabetes related foot problems. For people with diabetes, too much glucose in the blood can cause serious foot...
Diet Mistake Pictures: Crash Diets, High-Calorie Drinks, and More
Discover 10 common diet mistakes that may be preventing you from losing weight. Learn to avoid these diet blunders and watch the...
Heart Healthy Diet: 25 Foods You Should Eat
What foods are heart healthy? Learn what foods help protect your cardiovascular system from heart attack, coronary heart disease,...
Diet for Stress Management: Carbs, Nuts, and Other Stress-Relief Foods
While there are many ways to cope with stress, one strategy is to eat stress-fighting foods. Find out which foods to eat as part...
Fat-Burning Foods in Pictures: Blueberries, Green Tea, and More
Learn about fat-fighting foods such as grapefruit, hot peppers, vinegar, and more. Discover the benefits along with surprising...
Travel Tips for Better Diabetes Control
Traveling with diabetes can be intimidating, but it shouldn't stop you! Learn tips for packing your diabetic supplies, how to...
Diabetes Diet: 11 Low-Sugar Drink Ideas
Searching for low-sugar drink ideas? This pictures slideshow has eleven beverages ideal for people with diabetes and those...
Healthy Dieting Myths and Facts
Learn about healthy dieting myths and facts. Can't tell fact from fiction about weight loss and healthy eating? Discover the...
10 Tips for a Healthier Fast Food Diet
Losing weight is tough on the road. Fast food can't compare to the health of a well-planned, balanced diet. But if you must eat...
Healthy Living: 20 Common Health Myths Exposed
Can vitamin C cure colds? Read as we dispel the half-truths and common myths of health, from X-rays to eggs, from the...
Diabetes Management Tips and Preventing Complications
Learn 10 simple ways to better manage your diabetes. See tips for controlling blood sugar, diet and exercise and other helpful...
Worst Foods for Your Belly
Belly-fattening foods such as chips, beer, doughnuts and fatty red meat can kill a diet. See which foods are tough to resist,...
Pictures of 10 Muscle-Building Exercises for Diabetes
Watch this slideshow on Diabetes and Exercise. If you have diabetes, see how strengthening your muscles with these 10 weight...
Snacks With 100 Calories or Less
Reducing calories is an effective weight loss strategy. Here are 25 100-calorie snacks that offer quick, satisfying solutions to...
Worst-Appetizer Pictures: Spinach Dip, Potato Skins, and More
A tasty appetizer can be a great start to any meal--but some appetizers are diet disasters. Potato skins and cheese fries pack on...
How to Lose Weight Without Dieting: 24 Fast Facts
Weight loss without dieting? No diet, no problem. Learn the best way to lose weight with these weight loss tips designed to help...
Fat and Fats Quiz: Fatty Food & Body Fat Percentage
Take this online Fat & Fats Quiz to learn if you really are what you eat!
Protein Quiz: Foods High in Protein
Protein is a staple in our diets, but what happens if we get too much? Take this quiz to find out the truth about protein and...
Food Portion Distortion Quiz: Correct Serving Size
Are your portions deceiving you? Take the Food Portion Distortion Quiz to find out how and why gigantic portions trick you into...
Sugar Quiz: Facts on Diet & Sugar
Sugar lurks in surprising places. Take the Sugar Quiz to learn of the many ways sugar sneaks into your diet and see what you know...
Type 2 Diabetes: Test Your Medical IQ
What causes type 2 diabetes? Can it be prevented? Take this online quiz and challenge your knowledge of this common condition....
Salt Quiz: Test Your Diet IQ
Do you love salt? Take the online Salt Quiz to get the facts about dietary salts and sodium in fruits, vegetables, processed...
Superfoods Quiz: List of Top Superfoods
Take our Superfoods Quiz! Get to know how unprocessed, raw, organic foods and healthy drinks are rich in nutrients and dietary...
Diet and Nutrition Quiz: Plans & Facts
Even if you think you're getting enough fruits and vegetables per day, how can you be sure? Take the Diet & Nutrition Quiz to...
Diabetes Quiz: Test Your Medical IQ
Take the Diabetes Quiz and learn the causes, signs, symptoms, and types of this growing epidemic. What does diabetes have to do...
Diet-Wrecking Foods: Smoothies, Lattes, Popcorn, and More in Pictures
It may seem healthy, but is it really? Many food frauds masquerade as diet food. See 23 foods that seem healthy but can be...
Sugar Addiction Facts: Cravings, Hidden Sugar, and More in Pictures
Learn about sugar addiction to see why we often crave sweets and binge on carbs. Learn how sugar affects the brain and get tips...
Tips to Eat Healthy When You Dine Out in Pictures
Recognize the dangers of eating out and stay on your healthy diet at restaurants. Learn about healthy eating at restaurants,...
Pictures of Famous People With Diabetes
See pictures of celebrities that have been diagnosed with type 1 or type 2 diabetes including Mary Tyler Moore, Salma Hayek, and...
13 Easy Ways to Eat More Greens
Learn 13 easy ways to add more greens to your diet. Discover how to add kale, spinach, broccoli rabe and more into your diet.
Food Swaps for Meals and Snacks for Heart Health in Pictures
Explore 10 food swaps for heart-wise dining. Learn what food to buy and how to cook in order to make a big difference for your...
12 Reasons to Love the Mediterranean Diet in Pictures
The Mediterranean diet is a delicious way to eat healthy. We show you how to get the most from this diet with foods like olive...
Portion Control Tips: Lose Weight and Stick to Your Diet
Portion control can help with weight loss and help you stick to a healthy diet. But how much is too much? This photo guide will...
Vegetarian Diet: Tasty, Basic Choices in Pictures
Thinking about becoming a vegetarian? Compared to the general population, the typical vegetarian has a lower body mass index...
Slideshow: 25 Ways to Get Ready for Swimsuit Season
Discover 25 ways to get ready for swimsuit season. See exercises, diet tips, and other healthy beauty fixes that will motivate...
The Worst Foods in Your Fridge
What are the worst foods to eat in your fridge? From mayonnaise to ice cream and butter to processed lunch meats, learn about the...
High Protein Diets: Good or Bad?
Low-carb, high-protein diets are quite popular. High protein diets let you snack on protein-rich foods you love, but what are the...
Easy, Tasty Grilled Foods for Dinner Tonight in Pictures
Explore easy and tasty grilled foods. When your rushed to get dinner on the table, fire up the grill and use these delicious,...
Food Cravings Slideshow: Chocolate, Carbs, Salt, Sugar
Learn which food cravings can wreck your diet. Whether your craving something creamy or crunchy, sweet or salty, food cravings...
Low-Carb Snacks in Pictures
Interested in low-carb snacking? Here are some ideas about smart snacks that are filling and low in carbohydrates.
Fast-Food Sandwiches: Good and Bad Choices For Your Diet
Want to know what the good and bad fast-food sandwiches choices are? Our experts explore the nutrition facts of major restaurant...
Related Disease Conditions
Type 2 Diabetes Diet Plan
A type 2 diabetes diet or a type 2 diabetic diet is important for blood sugar (glucose) control in people with diabetes to prevent complications of diabetes. There are a variety of type 2 diabetes diet eating plans such as the Mediterranean diet, Paleo diet, ADA Diabetes Diet, and vegetarian diets.Learn about low and high glycemic index foods, what foods to eat, and what foods to avoid if you have type 2 diabetes.
Diabetes (Type 1 and Type 2)
Diabetes is a chronic condition characterized by high levels of sugar (glucose) in the blood. The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin dependent). Symptoms of diabetes include increased urine output, thirst, hunger, and fatigue. Treatment of diabetes depends on the type.
Diabetes Treatment (Type 1 and Type 2 Medications and Diet)
The major goal in treating diabetes is controlling elevated blood sugar without causing abnormally low levels of blood sugar. Type 1 diabetes is treated with: insulin, exercise, and a diabetic diet. Type 2 diabetes is first treated with: weight reduction, a diabetic diet, and exercise. When these measures fail to control the elevated blood sugar, oral medications are used. If oral medications are still insufficient, insulin medications are considered.
Type 1 vs Type 2 Diabetes (Similarities and Differences)
Diabetes mellitus is a metabolic condition in which a person's blood sugar (glucose) levels are too high. Over 29.1 million children and adults in the US have diabetes. Of that, 8.1 million people have diabetes and don't even know it. Type 1 diabetes (insulin-dependent, juvenile) is caused by a problem with insulin production by the pancreas. Type 2 diabetes (non-insulin dependent) is caused by: Eating a lot of foods and drinking beverages with simple carbohydrates (pizza, white breads, pastas, cereals, pastries, etc.) and simple sugars (donuts, candy, etc.) Consuming too many products with artificial sweeteners (We found out that they are bad for us!) Lack of activity Exercise Stress Genetics While the signs and symptoms of both types of diabetes are the same, which include: Increased urination Increased hunger Increased thirst Unexplained weight loss. However, the treatments are different. Type 1 diabetes is insulin dependent, which means a person with this type of diabetes requires treatment with insulin. People with type 2 diabetes require medication, lifestyle changes like eating a healthy diet, and getting regular exercise.
Type 2 Diabetes
Type 2 diabetes is a chronic condition that may be reversible with diet and lifestyle changes. Symptoms include excessive thirst, frequent urination, weight loss, fatigue, and an unusual odor to your urine. Most people don't know they have type 2 diabetes until they have a routine blood test. Treatment options include medications, a type 2 diabetes diet, and other lifestyle changes.
Diabetes and Foot Problems (Treatment)
Diabetes related foot problems can affect your health with two problems: diabetic neuropathy, where diabetes affects the nerves, and peripheral vascular disease, where diabetes affects the flow of blood. Common foot problems for people with diabetes include athlete's foot, fungal infection of nails, calluses, corns, blisters, bunions, dry skin, foot ulcers, hammertoes, ingrown toenails, and plantar warts.
Diabetic Neuropathy (Symptoms, Causes, Diagnosis, Treatment)
Diabetic neuropathy a condition in which nerve damage has occurred as a complication of diabetes. The pain from the nerve damage can be severe with tingling or numbness in the part of the body affected. Diabetic neuropathy can occur anywhere in the body. Diabetic neuropathy can cause symptoms like intense pain, numbness, burning, or tingling in the part of the body affected by the condition. There are four types of neuropathy include peripheral, autonomic, proximal and focal. Natural therapies and medications may help relieve the pain and other symptoms of diabetic neuropathy.
A diabetic diet, or diabetes diet helps keep blood glucose levels in the target range for patients. Exercise and medication may also help stabilize blood glucose levels. Keeping track of when you take your diabetic medicine, keeping track of food choices, eating the proper amount of fruits, vegetables, carbohydrates, and fats will also help maintain proper blood glucose levels. Foods that raise blood sugar levels are "high glycemic index foods;" examples include: Pumpkin Melons Popcorn Short-grain white rice Foods that help maintain good blood sugar levels are foods that are low on the glycemic index, for example: Rolled or steel-cut oats Many fruits Non-starchy vegetables Beans Legumes Lentils
Eye Problems and Diabetes
Diabetes and eye problems are generally caused by high blood sugar levels over an extended period of time. Types of eye problems in a person with diabetes include glaucoma, cataracts, and retinopathy. Examples of symptoms include blurred vision, headaches, eye aches, pain, halos around lights, loss of vision, watering eyes. Treatment for eye problems in people with diabetes depend on the type of eye problem. Prevention of eye problems include reducing blood pressure, cholesterol levels, quitting smoking, and maintaining proper blood glucose levels.
Diabetes and Kidney Disease
In the United States diabetes is the most common cause of kidney failure. High blood pressure and high levels of blood glucose increase the risk that a person with diabetes will eventually progress to kidney failure. Kidney disease in people with diabetes develops over the course of many years. albumin and eGFR are two key markers for kidney disease in people with diabetes. Controlling high blood pressure, blood pressure medications, a moderate protein diet, and compliant management of blood glucose can slow the progression of kidney disease. For those patients who's kidneys eventually fail, dialysis or kidney transplantation is the only option.
Type 2 Diabetes Medications (Side Effects, Differences)
Type 2 diabetes oral medications are prescribed to treat type 2 diabetes in conjuction with lifestyle changes like diet and exercise. There are nine classes of drugs approved for the treatment of type 2 diabetes. Examples of type 2 oral diabetes medications include acarbose (Precose), chlorpropamide (Diabinese), glipizide (Glucotrol, Glucotrol XL), and metformin (Glucophage). Side effects, drug interactions, warnings and precautions, dosage, and breastfeeding and pregnancy safety information should be reviewed prior to taking any medication.
Tips for Managing Type 1 and 2 Diabetes at Home
Managing your diabetes is a full time commitment. The goal of diabetic therapy is to control blood glucose levels and prevent the complications of diabetes. Information about exercise, diet, and medication will help you manage your diabetes better. Blood glucose reagent strips, blood glucose meters, urine glucose tests, tests for urinary ketones, continuous glucose sensors, and Hemoglobin A1C testing information will enable you to mange your diabetes at home successfully.
Diabetes: Caring for Your Diabetes at Special Times
Taking care of a disease such as diabetes is a life-long process. Learn how to care for yourself or loved one with diabetes in situations such as illness, work, school, travel, or a natural disaster.
Treatment & Diagnosis
- Food Portion Distortion FAQs
- Diet & Nutrition FAQs
- Superfoods FAQs
- Sugar FAQs
- Fat and Fats FAQs
- Diabetes FAQs
- Salt FAQs
- Protein FAQs
- Type 2 Diabetes FAQs
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Medication Disposal
- Dangers of Mixing Medications
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
Prevention & Wellness
- Metformin Still Best as First Type 2 Diabetes Treatment
- Which Diabetes Drug Is Best?
- Metformin Safer for Heart Than Other Common Type 2 Diabetes Drugs: Study
- Blood Thinner, Certain Diabetes Drugs Are a Bad Combo
- Tanzeum Approved for Type 2 Diabetes
- New Diabetes Drug Expected This Week
- Newer 'Second-Line' Diabetes Drug May Outperform Older Meds
- Metformin Outperforms Common Class of Diabetes Drugs in Study
- Prescription Meds Can Put on Unwanted Pounds
- Experimental Drug Shows Promise Against Type 2 Diabetes
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
FDA Prescribing Information