Fulvic Acid

Reviewed on 6/11/2021
Other Name(s):

Acide Fulvique, Ácido Fúlvico, Fulvosäure.


Fulvic acid is a yellow-brown substances found in natural material such as shilajit, soil, peat, coal, and bodies of water such as streams or lakes. Fulvic acid is formed when plants and animals decompose.

People take fulvic acid by mouth for brain disorders such as Alzheimer's disease, as well as respiratory tract infections, cancer, fatigue, heavy metal toxicity, allergies, and preventing a condition in which the body tissues do not receive enough oxygen (hypoxia). People also use fulvic acid on the skin for eczema.

How does it work?

Fulvic acid might have various effects in the body. Fulvic acid might block reactions in the body that cause allergy symptoms. It might also interrupt steps involved in the worsening of brain disorders such as dementia. Additionally, fulvic acid might reduce inflammation and prevent or slow the growth of cancer. Fulvic acid seems to have immune-stimulating and antioxidant effects.


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Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

  • Allergies. Early research shows that taking fulvic acid by mouth for 7 days might help reduce allergic reactions in people with allergies to pollen.
  • Eczema. Early research suggests that applying fulvic acid 5% to the skin twice daily for 4 weeks might improve some symptoms of eczema.
  • Alzheimer's disease.
  • Cancer.
  • Fatigue.
  • Heavy metal toxicity.
  • Preventing a condition in which the body tissues do not receive enough oxygen (hypoxia).
  • Respiratory tract infections.
  • Other conditions.
More evidence is needed to rate fulvic acid for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

Fulvic acid is POSSIBLY SAFE when taken by mouth or used on the skin for a few days.

Some people who have taking fulvic acid by mouth have experienced a headache or sore throat.


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Special Precautions & Warnings

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking fulvic acid if you are pregnant or breast feeding. Stay on the safe side and avoid use.

Autoimmune diseases: Fulvic acid might increase the activity of the immune system. In theory, fulvic acid might worsen some autoimmune diseases, such as multiple sclerosis, systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA). People with these conditions should be cautious or avoid fulvic acid altogether.

Kashin-Beck Disease: There is some concern that fulvic acid in drinking water might increase the risk of developing Kashin-Beck disease. It is thought that the risk is greatest in regions where people do not receive enough selenium.


Medications that decrease the immune system (Immunosuppressants)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Fulvic acid can stimulate the immune system. In theory, taking fulvic acid might decrease the effects of medications that decrease the immune system.

Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), and other corticosteroids (glucocorticoids).

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Some medications are taken to slow blood clotting. Fulvic acid might increase how quickly blood clots. Taking fulvic acid with these medications might reduce their effects and increase the risk of blood clots.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

Thyroid hormoneInteraction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Fulvic acid affects thyroid hormone levels. In theory, taking fulvic acid with thyroid hormone might interfere with therapy to make thyroid function normal. People receiving thyroid hormone should use fulvic acid cautiously.


The appropriate dose of fulvic acid depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses fulvic acid (in children/in adults). Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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