- 10 Common Allergy Triggers Slideshow Pictures
- Take the Quiz on Allergies
- Nasal Allergy Relief Products Slideshow
- What is fluticasone? How does it work (mechanism of action)?
- What are the uses for fluticasone?
- What are the side effects of fluticasone?
- What is the dosage for fluticasone?
- Which drugs or supplements interact with fluticasone?
- Is fluticasone safe to take if I'm pregnant or breastfeeding?
- What else should I know about fluticasone?
What is fluticasone? How does it work (mechanism of action)?
Fluticasone is a man-made corticosteroid. The exact mechanism of action of fluticasone is not known; however, it stimulates glucocorticoid receptors in humans that produces a potent anti-inflammatory response. Fluticasone also works on multiple cells and mediators that are responsible for the inflammatory symptoms of allergic rhinitis (sneezing, runny nose, etc). The FDA approved fluticasone in October 1994.
What are the uses for fluticasone?
Fluticasone is used for the management of nasal symptoms of seasonal or perennial, allergic and non-allergic rhinitis in adults and children of 4 years of age and older. Safe and effective use of fluticasone has not been established for children under the age of 4.
What are the side effects of fluticasone?
Side effects of fluticasone include:
- sore throat,
- nasal burning or nasal irritation,
- asthma symptoms, or
Some children may experience growth suppression from use of inhaled steroids.
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What is the dosage for fluticasone?
- Adults: The recommended dosing is 2 sprays per nostril daily. The maximum dose is 200 mcg/day (4 sprays). Maintenance therapy is 1 spray in each nostril daily.
- Adolescents and children 4 years of age and older: the recommended dosing is 1 spray per nostril daily (total dose 100 mcg.) Patients that do not respond adequately may increase to two sprays in each nostril once a day. The maximum dose is 200 mcg/day.
Is fluticasone safe to take if I'm pregnant or breastfeeding?
There are no adequate studies of fluticasone to determine its safety and effectiveness in pregnant women.
What else should I know about fluticasone?
- Fluticasone propionate nasal spray is available as a 16 gm bottle, providing a total of 120 sprays. Each spray contains 50 mcg of fluticasone propionate.
- Fluticasone propionate should be store between 4 C and 30 C (39 F and 86 F).
- Brand names for fluticasone propionate are Flonase and Flonase Allergy Relief.
- Flonase is available by prescription and over-the-counter (OTC).
Reference: FDA Prescribing Information.
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Fluticasone propionate nasal spray (Flonase, Flonase Allergy Relief) is a corticosteroid prescribed for the management of symptoms of seasonal or perennial allergic and non-allergic rhinitis. Side effects, drug interactions, dosage, safety during pregnancy, and safety in children should be reviewed prior to taking this medication.
Multimedia: Slideshows, Images & Quizzes
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Related Disease Conditions
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Treatment & Diagnosis
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Medications & Supplements
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- Drug Interactions
- Claritin (loratadine) vs. Zyrtec (cetirizine)
- Nasal Allergy Medications
- Advair Diskus, Advair HFA (fluticasone and salmeterol oral inhaler)
- budesonide nasal inhaler (Rhinocort Allergy, Rhinocort Aqua)
- flunisolide nasal spray, Aerospan (Nasalide, Aerobid, Aerobid HFA are discontinued)
- azelastine hydrochloride and fluticasone propionate (Dymista)
Prevention & Wellness
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Subscribe to MedicineNet's Allergy and Asthma Newsletter
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Top fluticasone propionate nasal inhaler-spray Related ArticlesComplete List
Know Your Allergy TriggersAllergies are an overreaction of the immune system where the body's defenses react to substances such as pollen, food and more. Learn about common allergy triggers and how you can avoid an allergy attack.
AllergyAn allergy refers to a misguided reaction by our immune system in response to bodily contact with certain foreign substances. When these allergens come in contact with the body, it causes the immune system to develop an allergic reaction in people who are allergic to it. It is estimated that 50 million North Americans are affected by allergic conditions. The parts of the body that are prone to react to allergies include the eyes, nose, lungs, skin, and stomach. Common allergic disorders include hay fever, asthma, allergic eyes, allergic eczema, hives, and allergic shock.
Allergy Treatment Begins At HomeAvoiding allergy triggers at home is one of the best ways to prevent allergy symptoms. Controlling temperature, humidity, and ventilation are a few ways to allergy-proof the home. Cleaning, vacuuming, and using HEPA air filters also helps control allergies.
budesonide nasal inhaler-spray
Budesonide nasal inhaler-spray (Rhinocort Allergy, Rhinocort Aqua) is a medication prescribed for the management of the symptoms of allergic rhinitis and the treatment and prevention of nasal polyps. Common side effects of budesonide include
- Nasal bleeding
- Sore Throat
Other side effects include:
- Upper respiratory infections
Drug interactions, dosage, and pregnancy and breastfeeding safety should be reviewed prior to using this drug.
Chronic rhinitis and post-nasal drip symptoms include:
- An itchy, runny nose
- Itchy ears, eyes, and throat
Seasonal allergic rhinitis (also called hay fever) usually is caused by pollen in the air. Perennial allergic rhinitis is a type of chronic rhinitis and is a year-round problem, often caused by indoor allergens, such as dust, animal dander, and pollens that may exist at the time. Treatment of chronic rhinitis and post nasal drip are dependent upon the type of rhinitis condition.
Claritin loratadine vs Zyrtec cetirizineClaritin (loratadine) and Zyrtec (cetirizine) are both second-generation antihistamines. Antihistamies are anti-allergy drugs, and loratadine and cetirizine both are used against hay fever, pollen-induced asthma, and hives. Learn about the side effects, dosage, and pregnancy safety information for Claritin and Zyrtec.
Cold, Flu, AllergyBefore treating a cold, the flu, or allergies with over-the-counter (OTC) medications, it's important to know what's causing the symptoms, which symptoms one wishes to relieve, and the active ingredients in the OTC product. Taking products that only contain the medications needed for relieving your symptoms prevents ingestion of unnecessary medications and reduces the chances of side effects.
Drug InteractionsDrug interactions occur frequently. Get facts about the types of drug interactions, what substances or other things that may interact with drugs such as OTC drug and prescription drugs, vitamins, food(s) (grapefruit), and laboratory tests. Find out how to protect yourself from potential drug interactions.
Drugs: What You Should Know About Your DrugsImportant information about your drugs should be reviewed prior to taking any prescription drug. Side effects, drug interactions, warnings and precauctions, dosage, what the drug is used for, what to do if you miss a dose, how the drug is to be stored, and generic vs. brand names.
flunisolide nasal sprayFlunisolide nasal spray (Aerospan [Nasalide, Aerobid, Aerobid HFA are discontinued]) is a corticosteroid in the form of an oral-metered dose inhaler for the treatment of asthma in adults and children; or as a nasal spray for treating allergic rhinitis. Side effects, dosing, warnings and precautions, and pregnancy information should be reviewed prior to taking this medication.
fluticasone and salmeterol oral inhaler
Advair Diskus, Advair HFA (fluticasone propionate and salmeterol oral inhaler) is an inhalant drug used to treat
- chronic bronchitis, and
- chronic obstructive pulmonary disease (COPD).
Side effects include:
- Sinus infection
- Skin reactions
- Taste changes
- Musculoskeletal pain
Drug interactions, warnings and precautions, and pregnancy and breastfeeding safety information should be reviewed prior to taking any medication.
Hay FeverHay fever (allergic rhinitis) is an irritation of the nose caused by pollen and is associated with the following allergic symptoms: nasal congestion, runny nose, sneezing, eye and nose itching, and tearing eyes. Avoidance of known allergens is the recommended treatment, but if this is not possible, antihistamines, decongestants, and nasal sprays may help alleviate symptoms.
How to Stop Coughing
Coughing is a reflex that helps a person clear their airways of irritants. There are many causes of an excessive or severe cough including:
- Irritants like
- cigarette and secondhand smoke
- air fresheners
- Medications like beta blockers and ACE inhibitors
- Medical conditions like
- the common cold
- lung cancer
- heart disease
Natural and home remedies that help cure and soothe a cough are:
Natural and home remedies to help cure and soothe a cough are:
- Stay hydrated
- Gargle saltwater
- Use cough drops or lozenges
- Use herbs and supplements like ginger, mint, licorice, and slippery elm
- Don't smoke
Over-the-counter products (OTC)to cure and soothe a cough include
- cough suppressants and expectorants, and
- anti-reflux drugs.
Prescription drugs that help cure a cough include
- narcotic medications,
- inhaled steroids, and
- anti-reflux drugs like proton pump inhibitors or PPIs, for example,
- omeprazole (Prilosec),
- rabeprazole (Aciphex), and
- pantoprazole (Protonix).
- Irritants like
Nasal Allergy MedicationsNasal allergy medications are used to relieve itching, sneezing, and nasal swelling associated with allergies. Antihistamines, decongestants, and steroids are different types of nasal allergy medications. Possible side effects of these medications include dryness, stuffiness, burning, bleeding, nervousness, and palpitations.
Nasal Allergy ReliefLearn how a combination of medication, preventing allergens, and allergy relief products can reduce allergy symptoms and help you feel better.
Nasal IrrigationNasal irrigation can relieve sinus symptoms associated with colds & allergies. Learn how nasal irrigation can help unclog sinuses and congestion.
Allergies SlideshowLearn 10 signs your allergies are out of control. See these surprising allergy symptoms and find out how to get relief for sneezing, congestion, watery eyes, and more.
SinusitisSinus infection (sinusitis) is caused by allergies, infection, and chemicals or other irritants of sinuses. Signs and symptoms are headache, fever, and facial tenderness, pressure, or pain. Treatments of sinus infections are generally with antibiotics and at times, home remedies.
What Is MucusMucus is a normal substance produced by lining tissues in the body. Excess mucus or mucus that is yellow, green, brown, or bloody may indicate a problem. Mucus production may increase when allergies, a cold, flu, cough, or sore throat are present. Antihistamines and cold and flu medications may help alleviate excess mucus. A neti pot may be used to decrease nasal congestion and clear mucus.