- What is fluticasone propionate-topical, and how does it work (mechanism of action)?
- What brand names are available for fluticasone propionate-topical?
- Is fluticasone propionate-topical available as a generic drug?
- Do I need a prescription for fluticasone propionate-topical?
- What are the side effects of fluticasone propionate-topical?
- What is the dosage for fluticasone propionate-topical?
- Is fluticasone propionate-topical safe to take if I'm pregnant or breastfeeding?
- What else should I know about fluticasone propionate-topical?
What is fluticasone propionate-topical, and how does it work (mechanism of action)?
Fluticasone propionate is a synthetic (man-made) corticosteroid that is used on the skin (topically). The naturally-occurring corticosteroid is cortisol or hydrocortisone produced by the adrenal gland. Corticosteroids have potent anti-inflammatory actions and also suppress the immune response. Similar drugs include betamethasone dipropionate (Diprolene), clobetasol propionate (Temovate), halobetasol propionate (Ultravate), betamethasone dipropionate (Diprosone), desoximetasone (Topicort), halcinonide (Halog), amcinonide (Cyclocort), triamcinolone acetonide (Kenalog), fluocinolone acetonide (Synalar), hydrocortisone butyrate (Locoid), hydrocortisone valerate (Westcort), and mometasone furoate (Elocon). The FDA approved topical fluticasone propionate in December, 1990.
What are the side effects of fluticasone propionate-topical?
WARNING Prolonged use or application of topical steroids to large surface areas can depress the ability of the body's adrenal glands to produce corticosteroids. This occurs because some of the fluticasone propionate is absorbed into the body and shuts off the production of the naturally occurring corticosteroids.Abruptly stopping hydrocortisone in these individuals can cause symptoms of corticosteroid insufficiency.
What is the dosage for fluticasone propionate-topical?
- Fluticasone is available as cream, lotion, and ointment to apply to the skin.
- It is usually applied one or two times a day to treat most skin conditions.
- As with other corticosteroid medicines, treatment should be discontinued when control is achieved.
- To avoid unwanted side effects, corticosteroid medicines should be used for the shortest duration possible to achieve the desired results.

SLIDESHOW
Types of Psoriasis: Medical Pictures and Treatments See SlideshowIs fluticasone propionate-topical safe to take if I'm pregnant or breastfeeding?
It is not known whether topical fluticasone can be excreted into human milk. Since many drugs are excreted into human milk topical fluticasone should be used cautiously in nursing mothers.
What else should I know about fluticasone propionate-topical?
What preparations of fluticasone propionate-topical are available?
- Topical cream: 0.05%
- Topical lotion: 0.05%
- Topical ointment: 0.05%
How should I keep fluticasone propionate-topical stored?
Fluticasone propionate topical preparations should be stored at room temperature between 15 C to 30 C (59 F and 86 F).
Summary
Fluticasone propionate (Cutivate) is a corticosteroid prescribed to treat symptoms such as itching, dryness, scaling, inflammation, and redness associated with skin conditions like allergic reactions, eczema, and insect or bug bites. Side effects, drug interactions, storage, dosing, and pregnancy and breastfeeding safety should be reviewed prior to taking this medication.
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Eczema (Atopic Dermatitis) Quiz:
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Skin Quiz: Acne, Dry Skin, Dandruff & More
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Related Disease Conditions
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Skin Rash
The word "rash" means an outbreak of red bumps on the body. The way people use this term, "a rash" can refer to many different skin conditions. The most common of these are scaly patches of skin and red, itchy bumps or patches all over the place.
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Dry Skin
Dry skin (xeroderma) may be caused by external factors, like cold temperatures, low humidity, harsh soaps, and certain medications, or internal factors, such as thyroid disease, diabetes, psoriasis, or Sjogren's syndrome. Symptoms and signs of dry skin include itching and red, cracked, or flaky skin. The main treatment for dry skin is frequent, daily lubrication of the skin.
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Eczema
Eczema refers to skin inflammation. There are many different types of eczema that produce symptoms and signs that range from oozing blisters to crusty plaques of skin. Treatment varies depending upon the type of eczema the person has.
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Is Eczema Contagious?
Eczema is a skin condition characterized by inflamed, rough skin patches that occasionally produce fluid-filled bumps that may ooze. There is no cure for eczema, though eczema may be treated with moisturization, eczema cream, and topical steroids.
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Are Skin Rashes Contagious?
Direct and indirect contact can spread some types of rashes from person to person. Rash treatment depends upon a rash's underlying cause. A rash that sheds large amounts of skin warrants urgent medical attention. Rashes can be either contagious or noncontagious. Noncontagious rashes include seborrheic dermatitis, atopic dermatitis, contact dermatitis, stasis dermatitis, psoriasis, nummular eczema, drug eruptions, hives, heat rash (miliaria), and diaper rash. Rashes usually considered contagious include molluscum contagiosum (viral), impetigo (bacterial), herpes (herpes simplex, types 1 and 2 viruses), rash caused by Neisseria meningitides (N. meningitides) (bacterial), rash and blisters that accompany shingles (herpes zoster virus), ringworm (fungal) infections (tinea), scabies (itch mite), chickenpox (viral), measles and rubella (viral), erythema infectiosum (viral), pityriasis rosea (viral), cellulitis and erysipelas (bacterial), lymphangitis (bacterial, and folliculitis (bacterial).
Treatment & Diagnosis
Medications & Supplements
- Topical Corticosteroids
- hydrocortisone valerate
- clobetasol (Cormax, Embeline, Temovate, Olux, Clobex)
- fluocinolone (eczema) oil - topical, Derma-Smoothe/FS
- Diprolene Lotion (betamethasone dipropionate)
- Side Effects of Flovent (fluticasone propionate) oral inhaler
- mometasone (Elocon)
- Trelegy Ellipta (fluticasone furoate)
- Topicort (desoximetasone cream, ointment, spray, gel)
- halobetasol - topical, Ultravate
- Cutivate (fluticasone propionate)
- ArmonAir Digihaler (fluticasone propionate inhalation powder)
Prevention & Wellness

Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
REFERENCE:
FDA Prescribing Information